Long non-coding RNA (lncRNA) and epithelial-mesenchymal transition (EMT) in colorectal cancer: a systematic review.

Stephen J O'BrienCampbell BishopJacob HallionCasey FiechterKatharina ScheurlenMason PaasJames BurtonSusan Galandiuk

Published in: Cancer biology & therapy (2020)

lncRNAs are major regulators of EMT and predictor adverse outcome in CRC patients. Future research must focus on delineating lncRNA function prior to potential clinical use.

Keyphrases

long non coding rna
epithelial mesenchymal transition
poor prognosis
transforming growth factor
end stage renal disease
newly diagnosed
ejection fraction
signaling pathway
prognostic factors
emergency department
transcription factor
long noncoding rna
current status
patient reported
network analysis