Study of the influence of NGF-β gene overexpression in human mesenchymal stem cells on the expression level of SOX1 and neural pathway genes.

Julia Morys Paulina Borkowska Aleksandra Zielinska Jan Kowalski

Published in: Molecular biology reports (2022)

The achieved overexpression of NGF in this study, led the modified MSC onto the neural pathway as well as caused a decrease of SOX1 expression and an increase of expression of genes related to neural differentiated cells.

Keyphrases

poor prognosis
mesenchymal stem cells
transcription factor
genome wide
stem cells
genome wide identification
cell proliferation
endothelial cells
induced apoptosis
growth factor
binding protein
copy number
umbilical cord
cell cycle arrest
cell therapy
signaling pathway