Engineering Gold Nanostructures for Cancer Treatment: Spherical Nanoparticles, Nanorods, and Atomically Precise Nanoclusters.
Wei HeGuanyu MaQuanli ShenZhenghua TangPublished in: Nanomaterials (Basel, Switzerland) (2022)
Cancer is a major global health issue and is a leading cause of mortality. It has been documented that various conventional treatments can be enhanced by incorporation with nanomaterials. Thanks to their rich optical properties, excellent biocompatibility, and tunable chemical reactivities, gold nanostructures have been gaining more and more research attention for cancer treatment in recent decades. In this review, we first summarize the recent progress in employing three typical gold nanostructures, namely spherical Au nanoparticles, Au nanorods, and atomically precise Au nanoclusters, for cancer diagnostics and therapeutics. Following that, the challenges and the future perspectives of this field are discussed. Finally, a brief conclusion is summarized at the end.
Keyphrases
- sensitive detection
- reduced graphene oxide
- global health
- papillary thyroid
- squamous cell
- quantum dots
- silver nanoparticles
- energy transfer
- squamous cell carcinoma
- cardiovascular events
- working memory
- small molecule
- lymph node metastasis
- fluorescent probe
- childhood cancer
- type diabetes
- visible light
- tissue engineering
- walled carbon nanotubes