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Application of antibody phage display to identify potential antigenic neural precursor cell proteins.

Ioannis PaspaltsisEvangelia KesidouOlga TouloumiRoza LagoudakiMarina BozikiMartina SamiotakiDimitra DafouTheodoros SklaviadisNikolaos Grigoriadis
Published in: Journal of biological research (Thessalonike, Greece) (2020)
Using a standard immunization protocol to administer NPCs antigens, and applying the Fab fragment phage display technique, we were able to isolate at least a monoclonal IgG Fab fragment, which interacts with different mouse brain proteins. It is not clear whether such antibodies are produced in the host organisms, following NPCs transplantation.
Keyphrases
  • pseudomonas aeruginosa
  • cell therapy
  • single cell
  • randomized controlled trial
  • gram negative
  • cystic fibrosis
  • stem cells
  • human health
  • immune response
  • risk assessment
  • binding protein
  • climate change
  • bone marrow