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A single intra-articular injection of 2.0% non-chemically modified sodium hyaluronate vs 0.8% hylan G-F 20 in the treatment of symptomatic knee osteoarthritis: A 6-month, multicenter, randomized, controlled non-inferiority trial.

Emmanuel MaheuBernard AvouacRenée Liliane DreiserThomas Bardin
Published in: PloS one (2019)
This clinical trial demonstrated the non-inferiority of a single intra-articular injection of SH vs hylan G-F 20 on the WOMAC A change from baseline at 6 months.
Keyphrases
  • knee osteoarthritis
  • clinical trial
  • double blind
  • phase iii
  • phase ii
  • open label
  • placebo controlled
  • study protocol
  • ultrasound guided
  • cross sectional