Skin pH-dependent Staphylococcus aureus abundance as predictor for increasing atopic dermatitis severity.
Claudia HülpüschKarolina TremmelGertrud HammelMadhumita BhattacharyyaAmedeo de TomassiThomas NussbaumerAvidan U NeumannMatthias ReigerClaudia Traidl-HoffmanPublished in: Allergy (2020)
Skin pH is tightly regulated by intrinsic factors and limits the abundance of S aureus. High baseline S aureus abundance in turn predicts an increase in AD severity over the study period. This underlines the importance and potential of sustained intervention regarding the skin pH and urges for larger studies linking skin pH and skin S aureus abundance to understand driving factors of disease progression.