Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer.

Noemi EiroMaria FraileSara Escudero-CernudaJuan Sendon-LagoLuis O GonzalezMaria Luisa Fernandez-SánchezFrancisco J Vizoso

Published in: Stem cell research & therapy (2024)

In conclusion, our data demonstrate the synergistic effect of the combination of CM-hUCESC with paclitaxel on TNBC and opens an opportunity to reduce the dose of the chemotherapeutic agents, which may decrease chemotherapy-related toxicity.

Keyphrases

mesenchymal stem cells
endothelial cells
chemotherapy induced
induced pluripotent stem cells
electronic health record
bone marrow
oxidative stress
locally advanced
pluripotent stem cells
big data
cancer therapy
umbilical cord
cell therapy
data analysis
drug delivery