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Loss of histone H3 trimethylation on lysine 27 and nuclear expression of transducin-like enhancer 1 in primary intracranial sarcoma, DICER1-mutant.

Sanda AlexandrescuDavid M MeredithHart G LidovRita AlaggioMariangela NovelloKeith L LigonSara O Vargas
Published in: Histopathology (2020)
We conclude that H3K27me3 and TLE1 immunostains, when utilised in combination, can be helpful diagnostic markers for primary intracranial sarcoma, DICER1-mutant.
Keyphrases
  • poor prognosis
  • binding protein
  • wild type
  • optic nerve
  • transcription factor
  • long non coding rna
  • amino acid
  • optical coherence tomography