Role of RXRβ in platelet function and arterial thrombosis.

Enzo LüsebrinkVerena WarmJoachim PircherAndreas EhrlichZhe ZhangJan StreckerPierre ChambonSteffen MassbergChristian SchulzTobias Petzold

Published in: Journal of thrombosis and haemostasis : JTH (2019)

Absence of the most abundant RXR receptor in mouse platelets, RXRβ, does not affect platelet function in vitro and thrombus formation in vivo. Furthermore, RXR agonists' mediated effects on platelet function are independent of RXRβ expression. Hence, our data do not support a significant contribution of RXRβ to arterial thrombosis in mice.

Keyphrases

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