The Exploration of a Novel Biodegradable Drug-Eluting Biliary Stent: Preliminary Work.
Chu-Hui ZengLin-Lin LiuHai-Dong ZhuGao-Jun TengPublished in: Cardiovascular and interventional radiology (2021)
The degradation rate of PLGA can be controlled by altering lactic acid/glycolic acid ratio. Overall, PLGA 50/50 and 70/30 degrade significantly faster than 80/20. PLGA can serve as an effective drug carrier for PTX while being the stent strut, and PTX can be slowly released as PLGA degrades.