DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts.

Amy Joanne LynhamSarah KnottJack F G UnderwoodLeon HubbardSharifah S AghaJonathan I BissonMarianne B M van den BreeSamuel J R A ChawnerNicholas CraddockMichael O'DonovanIan R Jones George KirovKate LangleyJoanna MartinFrances RiceNeil P RobertsAnita ThaparRichard AnneyMichael J OwenJeremy HallAntonio F Pardinas James T R Walters

Published in: BJPsych open (2023)

DRAGON-Data combines genetic and non-genetic information, and is available as a resource for research across traditional psychiatric diagnostic categories. Algorithms and pipelines used for data harmonisation are currently publicly available for the scientific community, and an appropriate data-sharing protocol will be developed as part of ongoing projects (DATAMIND) in partnership with Health Data Research UK.

Keyphrases

electronic health record
big data
mental health
randomized controlled trial
machine learning
copy number
genome wide
gene expression
high throughput
artificial intelligence