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DRAGON-Data: a platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts.

Amy Joanne LynhamSarah KnottJack F G UnderwoodLeon HubbardSharifah S AghaJonathan I BissonMarianne B M van den BreeSamuel J R A ChawnerNicholas CraddockMichael O'DonovanIan R JonesGeorge KirovKate LangleyJoanna MartinFrances RiceNeil P RobertsAnita ThaparRichard AnneyMichael J OwenJeremy HallAntonio F PardinasJames T R Walters
Published in: BJPsych open (2023)
DRAGON-Data combines genetic and non-genetic information, and is available as a resource for research across traditional psychiatric diagnostic categories. Algorithms and pipelines used for data harmonisation are currently publicly available for the scientific community, and an appropriate data-sharing protocol will be developed as part of ongoing projects (DATAMIND) in partnership with Health Data Research UK.
Keyphrases
  • electronic health record
  • big data
  • mental health
  • randomized controlled trial
  • machine learning
  • copy number
  • genome wide
  • gene expression
  • high throughput
  • artificial intelligence