Expression of MAGE A1 to MAGE A10 in the Forceps Biopsy and Bronchoalveolar Lavage Specimens from Patients with the Central Lung Tumor.

Gondo Mastutik Alphania Rahniayu Isnin Anang Marhana Mochamad Amin Siti Eriaty Nur Ruslan Heru Fajar Trianto

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

The MAGE A subtype family genes are highly expressed in central lung tumor patients from FB and BAL specimens, even in specimens that were diagnosed with no malignant cells. All BAL specimens were diagnosed as no malignant cells, but expression of the MAGE A subfamily genes was found in more than 80% of the specimens. These observations suggest that combining histopathological and molecular examination could improve the diagnosis of lung malignancy.

Keyphrases

fine needle aspiration
induced apoptosis
poor prognosis
cell cycle arrest
end stage renal disease
ultrasound guided
genome wide
newly diagnosed
genome wide identification
cell death
peritoneal dialysis
gene expression
oxidative stress
single molecule
long non coding rna
bioinformatics analysis