The effectiveness of phototherapy for surface decontamination against SARS-Cov-2. A systematic review.
Susyane Vieira de OliveiraFilipe Danilo das NevesDaniela Carvalho Dos SantosMariana Bernardes Batista MonteiroMaristela S SchaufelbergerBeatriz Nascimento MottaIgor Pereira de OliveiraMaria Fernanda Setúbal Destro RodriguesAdriana Lino Dos Santos FrancoRebeca Boltes CecattoPublished in: Journal of biophotonics (2022)
COVID-19 appeared in December 2019, needing efforts of science. Besides, a range of light therapies (PDT, Ultraviolet UV, Laser) has shown scientific alternatives to conventional decontamination therapies. METHODS: Investigating the efficacy of light-based therapies for environment decontamination against SARS-CoV2, a PRISMA systematic review of Phototherapies against SARS-CoV or MERS-CoV species discussing changes in viral RT-PCR was done. After searching MEDLINE/PubMed, EMBASE, and LILACS we have found studies about cell cultures irradiation (18), blood components irradiation (10), N95 masks decontamination (03), inanimate surface decontamination (03), aerosols decontamination (03), hospital rooms irradiation (01) with PDT, LED, and UV therapy. The best quality results showed an effective low time and dose UV irradiation for environments and inanimate surfaces without human persons as long as the devices have safety elements dependent on the surfaces, viral charge, humidity, radiant exposure. To interpersonal contamination in humans, PDT or LED therapy seems very promising and are encouraged.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- systematic review
- photodynamic therapy
- meta analyses
- healthcare
- endothelial cells
- randomized controlled trial
- radiation induced
- public health
- biofilm formation
- quality improvement
- stem cells
- cell therapy
- mass spectrometry
- drinking water
- risk assessment
- radiation therapy
- pseudomonas aeruginosa
- mesenchymal stem cells
- climate change
- staphylococcus aureus
- candida albicans
- acute care
- electronic health record
- genetic diversity
- smoking cessation