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Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium.

Ling-Wei ChenAdrien M AubertNitin ShivappaJonathan Yoan BernardSara M Mensink-BoutAisling A GeraghtyJohn MeheganMatthew J SudermanPolańska KingaWojciech HankeElzbieta TrafalskaCaroline L ReltonSarah R CrozierNicholas C W HarveyCyrus CooperLiesbeth DuijtsBarbara HeudeJames R HébertFionnuala M McAuliffeCecily C KelleherCatherine M Phillips
Published in: PLoS medicine (2021)
In this cohort study, we observed that maternal diet that is of low quality and high inflammatory potential is associated with lower offspring birth size and higher risk of offspring being born SGA in this multicenter meta-analysis using harmonized IPD. Improving overall maternal dietary pattern based on predefined criteria may optimize fetal growth and avert substantial healthcare burden associated with adverse birth outcomes.
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