Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival.

T Jeethy RamAsha LekshmiPramod DarvinPrakash RajappanK M Jagathnath KrishnaT M AnoopPaul AugustineArun Peter MathewKurian CherianRexeena V BhargavanThara SomanathanM Radhakrishna PillaiT R Santhosh KumarK Sujathan

Published in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2023)

Tumor progression dependent expression pattern of galectin 3 was found to indicate prognosis. Co-expression of galectin-3 and vimentin in tumor cells promotes tumor dissemination, survival and its metastatic capability in TNBCs.

Keyphrases

poor prognosis
long non coding rna
breast cancer cells
squamous cell carcinoma
small cell lung cancer
binding protein