An Immune Gene Expression Risk Score for Distant Metastases after Radiotherapy for Cervical Cancer.
Jelena LukovicMelania PintilieKathy HanAnthony W FylesJeffrey P BruceRene QuevedoTrevor J PughChristina S FjeldboHeidi LyngMichael F MilosevicPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
The immune metastatic risk score addresses important challenges in the treatment of cervical cancer-identifying patients at high risk of DM after radiotherapy. The findings of this study indicate that high tumor mutational burden and a "cold," immune-excluded tumor microenvironment influence distant metastatic recurrence. Further validation of the risk score is needed.