Downregulation of inflammatory markers by conjugated linoleic acid isomers in human cultured astrocytes.
Francesca SabaAnnarita SiriguRita PillaiPaola CariaLina CordedduGianfranca CartaElisabetta MurruValeria SogosSebastiano BanniPublished in: Nutritional neuroscience (2017)
Current data demonstrate that CLA isomers, particularly t10,c12, may affect neuroinflammation by reducing the pro-inflammatory molecules in cultured astrocytes, suggesting a potential nutritional role of CLA isomers in modulating the astrocyte inflammatory response.
Keyphrases
- endothelial cells
- inflammatory response
- lipopolysaccharide induced
- lps induced
- signaling pathway
- cell proliferation
- traumatic brain injury
- photodynamic therapy
- electronic health record
- cognitive impairment
- big data
- pluripotent stem cells
- climate change
- immune response
- cerebral ischemia
- blood brain barrier
- artificial intelligence