Effects of Placenta-Derived Human Amniotic Epithelial Cells on the Wound Healing Process and TGF-β Induced Scar Formation in Murine Ischemic-Reperfusion Injury Model.
Felor BiniazanFarzad RajaeiShahram DarabiAmirhesam BabajaniMahboubeh MashayekhiNasim VousooghiMohammad-Amin AbdollahifarMaryam SalimiHassan NiknejadPublished in: Stem cell reviews and reports (2022)
These results suggest that hAECs can promote re-epithelialization and wound closure in an animal model of PU. They also reduced scar formation during wound healing by reducing the expression of TGF-β1/ TGF-β3 ratio.
Keyphrases
- wound healing
- transforming growth factor
- cerebral ischemia
- poor prognosis
- acute myocardial infarction
- epithelial mesenchymal transition
- heart failure
- diabetic rats
- induced pluripotent stem cells
- drug induced
- mesenchymal stem cells
- ischemia reperfusion injury
- blood brain barrier
- signaling pathway
- binding protein
- coronary artery disease
- umbilical cord
- long non coding rna