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Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling.

Amin H NassarCatherine B MeadorXintao QiuJi-Heui SeoMatthew P DavidsohnHunter SavignanoGitanjali LakshminarayananHeather M McClureJohn CanniffBrad FortunatoRong LiMandeep K BanwaitKarl SemaanMarc EidHenry W LongYin Pun HungNavin R MahadevanDavid A BarbieMatthew G OserZofia PiotrowskaToni K ChoueiriSylvan C BacaAaron N HataMatthew L FreedmanJacob E Berchuck
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
These data demonstrate the feasibility of detecting small cell transformation in patients with EGFRm LUAD through epigenomic cfDNA profiling of 1 ml of patient plasma.
Keyphrases
  • single cell
  • cell therapy
  • small cell lung cancer
  • case report
  • electronic health record
  • stem cells
  • tyrosine kinase
  • machine learning
  • mesenchymal stem cells
  • bone marrow