Jacob E Berchuck

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 22

Top Topics

African American

Dna Methylation

Circulating Tumor

Immune Response

Top Venues

Nature communications

Nature medicine

Clinical cancer research : an official journal of the American Association for Cancer Research

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Daniel Boiarsky, Alok K Tewari, Doga C Gulhan, Ziad Bakouny, Guruprasad Ananda, Hunter Savignano, Gitanjali Lakshminarayanan, Heather M McClure, Rebecca Silver, Toni K Choueiri, Mary-Ellen Taplin, Peter J Park, Jacob E Berchuck
A panel-based mutational signature of homologous recombination deficiency associates with response to PARP inhibition in metastatic castration-resistant prostate cancer. The Prostate (2024)
Amin H Nassar, Catherine B Meador, Xintao Qiu, Ji-Heui Seo, Matthew P Davidsohn, Hunter Savignano, Gitanjali Lakshminarayanan, Heather M McClure, John Canniff, Brad Fortunato, Rong Li, Mandeep K Banwait, Karl Semaan, Marc Eid, Henry W Long, Yin Pun Hung, Navin R Mahadevan, David A Barbie, Matthew G Oser, Zofia Piotrowska, Toni K Choueiri, Sylvan C Baca, Aaron N Hata, Matthew L Freedman, Jacob E Berchuck
Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (17) (2024)
Amin H Nassar, Catherine B Meador, Xintao Qiu, Ji-Heui Seo, Matthew P Davidsohn, Hunter Savignano, Gitanjali Lakshminarayanan, Heather M McClure, John Canniff, Brad Fortunato, Rong Li, Mandeep K Banwait, Karl Semaan, Marc Eid, Henry W Long, Yin Pun Hung, Navin R Mahadevan, David A Barbie, Matthew G Oser, Zofia Piotrowska, Toni K Choueiri, Sylvan C Baca, Aaron N Hata, Matthew L Freedman, Jacob E Berchuck
Detecting small cell transformation in patients with advanced EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Sylvan C Baca, Ji-Heui Seo, Matthew P Davidsohn, Brad Fortunato, Karl Semaan, Shahabbedin Sotudian, Gitanjali Lakshminarayanan, Miklos Diossy, Xintao Qiu, Talal El Zarif, Hunter Savignano, John Canniff, Ikenna Madueke, Renee Maria Saliby, Ziwei Zhang, Rong Li, Yijia Jiang, Len Taing, Mark Awad, Cindy H Chau, James A Decaprio, William Douglas Figg, Tim F Greten, Aaron N Hata, F Stephen Hodi, Melissa E Hughes, Keith L Ligon, Nancy Lin, Kimmie Ng, Matthew G Oser, Catherine Meador, Heather A Parsons, Mark M Pomerantz, Arun Rajan, Jerome Ritz, Manisha Thakuria, Sara M Tolaney, Patrick Y Wen, Henry W Long, Jacob E Berchuck, Zoltan Szallasi, Toni K Choueiri, Matthew L Freedman
Liquid biopsy epigenomic profiling for cancer subtyping. Nature medicine (2023)
Amin H Nassar, Sarah Abou Alaiwi, Sylvan C Baca, Elio Adib, Rosario I Corona, Ji-Heui Seo, Marcos A S Fonseca, Sándor Spisák, Talal El Zarif, Viktoria Tisza, David A Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G Matar, Andres Acosta, Sachet A Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E Berchuck, Edward O'Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S Hirsch, Mark Pomerantz, Elizabeth P Henske, Alexander Gusev, Kate Lawrenson, Toni K Choueiri, David J Kwiatkowski, Matthew L Freedman
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nature communications 14 (1) (2023)
Amin H Nassar, Sarah Abou Alaiwi, Sylvan C Baca, Elio Adib, Rosario I Corona, Ji-Heui Seo, Marcos A S Fonseca, Sándor Spisák, Talal El Zarif, Viktoria Tisza, David A Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G Matar, Andres Acosta, Sachet A Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E Berchuck, Edward O'Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S Hirsch, Mark Pomerantz, Elizabeth P Henske, Alexander Gusev, Kate Lawrenson, Toni K Choueiri, David J Kwiatkowski, Matthew L Freedman
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nature communications 14 (1) (2023)
Amin H Nassar, Sarah Abou Alaiwi, Sylvan C Baca, Elio Adib, Rosario I Corona, Ji-Heui Seo, Marcos A S Fonseca, Sándor Spisák, Talal El Zarif, Viktoria Tisza, David A Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G Matar, Andres Acosta, Sachet A Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E Berchuck, Edward O'Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S Hirsch, Mark Pomerantz, Elizabeth P Henske, Alexander Gusev, Kate Lawrenson, Toni K Choueiri, David J Kwiatkowski, Matthew L Freedman
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nature communications 14 (1) (2023)
Amin H Nassar, Sarah Abou Alaiwi, Sylvan C Baca, Elio Adib, Rosario I Corona, Ji-Heui Seo, Marcos A S Fonseca, Sándor Spisák, Talal El Zarif, Viktoria Tisza, David A Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G Matar, Andres Acosta, Sachet A Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E Berchuck, Edward O'Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S Hirsch, Mark Pomerantz, Elizabeth P Henske, Alexander Gusev, Kate Lawrenson, Toni K Choueiri, David J Kwiatkowski, Matthew L Freedman
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nature communications 14 (1) (2023)
Sylvan C Baca, Ji-Heui Seo, Matthew P Davidsohn, Brad Fortunato, Karl Semaan, Shahabbedin Sotudian, Gitanjali Lakshminarayanan, Miklos Diossy, Xintao Qiu, Talal El Zarif, Hunter Savignano, John Canniff, Ikenna Madueke, Renee Maria Saliby, Ziwei Zhang, Rong Li, Yijia Jiang, Len Taing, Mark Awad, Cindy H Chau, James A Decaprio, William Douglas Figg, Tim F Greten, Aaron N Hata, F Stephen Hodi, Melissa E Hughes, Keith L Ligon, Nancy Lin, Kimmie Ng, Matthew G Oser, Catherine Meador, Heather A Parsons, Mark M Pomerantz, Arun Rajan, Jerome Ritz, Manisha Thakuria, Sara M Tolaney, Patrick Y Wen, Henry W Long, Jacob E Berchuck, Zoltan Szallasi, Toni K Choueiri, Matthew L Freedman
Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping. Nature medicine (2023)
Amin H Nassar, Sarah Abou Alaiwi, Sylvan C Baca, Elio Adib, Rosario I Corona, Ji-Heui Seo, Marcos A S Fonseca, Sándor Spisák, Talal El Zarif, Viktoria Tisza, David A Braun, Heng Du, Monica He, Abdallah Flaifel, Michel Alchoueiry, Thomas Denize, Sayed G Matar, Andres Acosta, Sachet A Shukla, Yue Hou, John Steinharter, Gabrielle Bouchard, Jacob E Berchuck, Edward O'Connor, Connor Bell, Pier Vitale Nuzzo, Gwo-Shu Mary Lee, Sabina Signoretti, Michelle S Hirsch, Mark Pomerantz, Elizabeth P Henske, Alexander Gusev, Kate Lawrenson, Toni K Choueiri, David J Kwiatkowski, Matthew L Freedman
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nature communications 14 (1) (2023)
Jacob E Berchuck, Daniel Boiarsky, Rebecca Silver, Rajitha Sunkara, Heather M McClure, Harrison K Tsai, Stephanie E Siegmund, Alok K Tewari, Jonathan Andrew Nowak, Neal I Lindeman, Huma Q Rana, Atish D Choudhury, Mark M Pomerantz, Matthew L Freedman, Eliezer Van Allen, Mary-Ellen Taplin
Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer. JCO precision oncology 6 (2022)
Navonil DeSarkar, Robert D Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J Kreitzman, Jay F Sarthy, Minjeong Ko, Sandipan Brahma, Michael P Meers, Derek H Janssens, Lisa S Ang, Ilsa M Coleman, Arnab Bose, Ruth F Dumpit, Jared M Lucas, Talina A Nunez, Holly M Nguyen, Heather M McClure, Colin C Pritchard, Michael Thomas Schweizer, Colm Morrissey, Atish D Choudhury, Sylvan C Baca, Jacob E Berchuck, Matthew L Freedman, Kami Ahmad, Michael C Haffner, Robert B Montgomery, Eva Corey, Steven Henikoff, Peter S Nelson, Gavin Ha
Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes. Cancer discovery (2022)
Xiaodong Lu, Ka-Wing Fong, Galina Gritsina, Fang Wang, Sylvan C Baca, Lourdes T Brea, Jacob E Berchuck, Sándor Spisák, Jenny Ross, Colm Morrissey, Eva Corey, Navdeep S Chandel, William J Catalona, Ximing Yang, Matthew L Freedman, Jonathan C Zhao, Jindan Yu
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer. Nature genetics 54 (5) (2022)
Christopher T Su, Emily Nizialek, Jacob E Berchuck, Panagiotis J Vlachostergios, Ryan Ashkar, Alexandra O Sokolova, Pedro C Barata, Rahul R Aggarwal, Rana R McKay, Neeraj Agarwal, Heather M McClure, Nellie N Nafissi, Alan H Bryce, A Oliver Sartor, Nicolas Sayegh, Heather H Cheng, Nabil Adra, Cora N Sternberg, Mary-Ellen Taplin, Marcin Cieslik, Ajjai S Alva, Emmanuel S Antonarakis
Differential responses to taxanes and PARP inhibitors in ATM- versus BRCA2-mutated metastatic castrate-resistant prostate cancer. The Prostate (2022)
Jacob E Berchuck, Sylvan C Baca, Heather M McClure, Keegan Korthauer, Harrison K Tsai, Pier Vitale Nuzzo, Kaitlin M Kelleher, Monica He, John A Steinharter, Soumya Zacharia, Sándor Spisák, Ji-Heui Seo, Vincenza Conteduca, Olivier Elemento, Joonghoon Auh, Michael Sigouros, Eva Corey, Michelle S Hirsch, Mary-Ellen Taplin, Toni K Choueiri, Mark M Pomerantz, Himisha Beltran, Matthew L Freedman
Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (5) (2022)
Jacob E Berchuck, Elio Adib, Sarah Abou Alaiwi, Amit K Dash, Jin Na Shin, Dallin Lowder, Collin McColl, Patricia D Castro, Ryan Carelli, Elisa Benedetti, Jenny Deng, Matthew Robertson, Sylvan C Baca, Connor Bell, Heather M McClure, Amin H Nassar, Matthew P Davidsohn, Gitanjali Lakshminarayanan, Kinza Rizwan, Darlene G Skapura, Sandra L Grimm, Christel M Davis, Erik A Ehli, Kaitlin M Kelleher, Ji-Heui Seo, Nicholas Mitsiades, Cristian Coarfa, Mark M Pomerantz, Massimo Loda, Michael Ittmann, Matthew L Freedman, Salma Kaochar
The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response. Cancer research 82 (16) (2022)
Sylvan C Baca, David Y Takeda, Ji-Heui Seo, Justin Hwang, Sheng Yu Ku, Rand Arafeh, Taylor Arnoff, Supreet Agarwal, Connor Bell, Edward O'Connor, Xintao Qiu, Sarah Abou Alaiwi, Rosario I Corona, Marcos A S Fonseca, Claudia Giambartolomei, Paloma Cejas, Klothilda Lim, Monica He, Anjali Sheahan, Amin H Nassar, Jacob E Berchuck, Lisha Brown, Holly M Nguyen, Ilsa M Coleman, Arja Kaipainen, Navonil De Sarkar, Peter S Nelson, Colm Morrissey, Keegan Korthauer, Mark M Pomerantz, Leigh Ellis, Bogdan Pasaniuc, Kate Lawrenson, Kathleen Kelly, Amina Zoubeidi, William C Hahn, Himisha Beltran, Henry W Long, Myles Brown, Eva Corey, Matthew L Freedman
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer. Nature communications 12 (1) (2021)
Ziad Bakouny, David A Braun, Sachet A Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie I Vokes, Jackson Nyman, Wanling Xie, Amin H Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant'Angelo, Juliet Forman, Jacob E Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L Chang, Xiao X Wei, Bradley A McGregor, Lauren C Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S Hirsch, Matthew L Freedman, Michael B Atkins, Catherine J Wu, Thai H Ho, W Marston Linehan, David F McDermott, Daniel Y C Heng, Srinivas R Viswanathan, Sabina Signoretti, Eliezer Van Allen, Toni K Choueiri
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nature communications 12 (1) (2021)
Jacob E Berchuck, Paul V Viscuse, Himisha Beltran, Ana M Aparicio
Clinical considerations for the management of androgen indifferent prostate cancer. Prostate cancer and prostatic diseases 24 (3) (2021)
Fadi Taza, Albert E Holler, Wei Fu, Hao Wang, Nabil Adra, Costantine Albany, Ryan Ashkar, Heather H Cheng, Alexandra O Sokolova, Archana M Agarwal, Adam Kessel, Alan H Bryce, Nellie Nafissi, Pedro C Barata, A Oliver Sartor, Diogo Assed Bastos, Oren Smaletz, Jacob E Berchuck, Mary-Ellen Taplin, Rahul R Aggarwal, Cora N Sternberg, Panagiotis J Vlachostergios, Ajjai S Alva, Christopher T Su, Catherine Handy Marshall, Emmanuel S Antonarakis
Differential Activity of PARP Inhibitors in BRCA1- Versus BRCA2-Altered Metastatic Castration-Resistant Prostate Cancer. JCO precision oncology 5 (2021)
Sarah Abou Alaiwi, Amin H Nassar, Wanling Xie, Ziad Bakouny, Jacob E Berchuck, David A Braun, Sylvan C Baca, Pier Vitale Nuzzo, Ronan Flippot, Tarek H Mouhieddine, Liam F Spurr, Yvonne Y Li, Taiwen Li, Abdallah Flaifel, John A Steinharter, Claire A Margolis, Natalie I Vokes, Heng Du, Sachet A Shukla, Andrew D Cherniak, Guru Sonpavde, Robert I Haddad, Mark M Awad, Marios Giannakis, F Stephen Hodi, X Shirley Liu, Sabina Signoretti, Cigall Kadoch, Matthew L Freedman, David J Kwiatkowski, Eliezer M Van Allen, Toni K Choueiri
Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors. Cancer immunology research 8 (8) (2020)
Pier Vitale Nuzzo, Jacob E Berchuck, Keegan Korthauer, Sandor Spisak, Amin H Nassar, Sarah Abou Alaiwi, Ankur Chakravarthy, Shu Yi Shen, Ziad Bakouny, Francesco Boccardo, John Steinharter, Gabrielle Bouchard, Catherine R Curran, Wenting Pan, Sylvan C Baca, Ji-Heui Seo, Gwo-Shu Mary Lee, M Dror Michaelson, Steven L Chang, Sushrut S Waikar, Guru Sonpavde, Rafael A Irizarry, Mark Pomerantz, Daniel D De Carvalho, Toni K Choueiri, Matthew L Freedman
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nature medicine 26 (7) (2020)