Fractionated Proton Radiation Therapy and Hearing Preservation for Vestibular Schwannoma: Preliminary Analysis of a Prospective Phase 2 Clinical Trial.

Anurag SarafLuke R G PikeKevin H FranckNora K HorickBeow Y YeapBarbara C FullertonIrene S WangMohamed E AbazeedMichael J McKennaWilliam A MehanScott R PlotkinJay S LoefflerHelen A Shih

Published in: Neurosurgery (2022)

FPRT for VS did not meet the goal of serviceable hearing preservation. Higher cochlea doses trended to worsening hearing preservation, suggesting that dose to cochlea correlates with hearing preservation independent of treatment modality.

Keyphrases

hearing loss
radiation therapy
clinical trial
randomized controlled trial
squamous cell carcinoma
radiation induced
locally advanced
replacement therapy