Dynamics of IGF signalling during the ovulatory peak in women undergoing ovarian stimulation.

Jane Alrø BøtkjærLiv la Cour PoulsenPernille Rimmer NoerMarie Louise GrøndahlAnne Lis Mikkelsen EnglundStephen FranksKate HardyClaus OxvigClaus Yding Andersen

Published in: The Journal of clinical endocrinology and metabolism (2024)

These data suggest that downregulation of IGF signalling mediated by increased STC1 expression is instrumental for the sudden cessation in GC proliferation and onset of differentiation during the ovulatory peak.

Keyphrases

binding protein
signaling pathway
pi k akt
poor prognosis
polycystic ovary syndrome
growth hormone
cell proliferation
electronic health record
big data
pregnancy outcomes
pregnant women
skeletal muscle
gas chromatography
mass spectrometry
adipose tissue