Caryocar brasiliense Cambess. Pulp Oil Supplementation Reduces Total Cholesterol, LDL-c, and Non-HDL-c in Animals.
Gabriela Torres SilvaCarolina Di Pietro FernandesPriscila Aiko HianeKarine de Cássia Freitas GielowPriscila Silva FigueiredoAline Carla InadaWander Fernando FiliúIriani Rodrigues MaldonadeÂngela Alves NunesLincoln Carlos Silva de OliveiraAnderson Rodrigues Lima CairesFlavio MichelsCamila Jordão CândidoLeandro Fontoura CavalheiroMarcel Arakaki AsatoJuliana Rodrigues DonadonBernardo Bacelar de FariaMariana Bento TataraJulio Henrique Rosa CrodaArnildo PottCarlos Eduardo Domingues NazárioRita de Cássia Avellaneda GuimarãesPublished in: Molecules (Basel, Switzerland) (2020)
The fruit of Caryocar brasiliense Cambess. is a source of oil with active compounds that are protective to the organism. In our work, we analyzed the physicochemical characteristics and evaluated the effects of supplementation with C. brasiliense oil in an animal model. We characterized the oil by indices of quality and identity, optical techniques of absorption spectroscopy in the UV-Vis region and fluorescence, and thermogravimetry/derived thermogravimetry (TG/DTG). For the animal experiment, we utilized mice (Mus musculus) supplemented with lipidic source in different dosages. The results demonstrated that C. brasiliense oil is an alternative source for human consumption and presents excellent oxidative stability. Primarily, it exhibited oleic MFA (53.56%) and palmitic SFA (37.78%). The oil level of tocopherols and tocotrienols was superior to the carotenoids. The supplementation with C. brasiliense oil reduced the levels of total cholesterol, LDL-c, and non-HDL-c. Regarding visceral fats and adiposity index, the treatment synergically supplemented with olive oil and C. brasiliense oil (OO + CO) obtained the best result. Therefore, C. brasiliense oil is a high quality product for consumption. Its supplementation promotes beneficial effects mainly on the lipidic profile.