Topical essential fatty acid oil on wounds: Local and systemic effects.
Bruno Grosselli LaniaJoseane MorariAmanda Roberta de AlmeidaMarilene Neves da SilvaGislaine Vieira-DamianiKarina de Almeida LinsCarlos Lenz CésarLício Augusto VellosoNilson Borlina MaiaMaria Letícia CintraPaulo Eduardo Neves Ferreira VelhoPublished in: PloS one (2019)
EFA treatment induces topical (observed by local IGF-1, leptin, IL-6 and IFN-γ production) and systemic effects, lowering IL-6 levels in the serum. As the oil is widely used to shorten ulcer healing time, studies are needed to evaluate the treatment safety and possible undesired effects.