A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.

Xiao-Xin YangXiang XuMei-Fang WangHua-Zhen XuXing-Chun PengNing HanTing-Ting YuLiu-Gen LiQi-Rui LiXiao ChenYu WenTong-Fei Li

Published in: Journal of nanobiotechnology (2022)

In summary, DHA@MIL-101 nanoreactor boosts CDT and ferroptosis for synergistic cancer therapy by molecular amplifier DHA. This work provides a novel and effective approach for synergistic CDT-ferroptosis with Chinese herbal monomer-DHA and Nanomedicine.

Keyphrases

cancer therapy
cell death
drug delivery
fatty acid
single molecule
stem cells
solid phase extraction