Epithelial expression and role of secreted STC1 on asthma airway hyperresponsiveness through calcium channel modulation.

Jiayan XuYaqi MengMan JiaJie JiangYi YangYingwei OuYunhui WuXiaoyi YanMao HuangIan M AdcockXin Yao

Published in: Allergy (2021)

Our data indicate that STC1 deficiency in asthmatic airways promotes STIM1 hyperactivity, enhanced ASM contraction, and AHR. STC1 may be a candidate EpDRF.

Keyphrases

lung function
poor prognosis
cystic fibrosis
chronic obstructive pulmonary disease
big data
smooth muscle
binding protein
allergic rhinitis
data analysis
artificial intelligence