Deciphering the role of RNA structure in translation efficiency.
Jianan LinYang ChenYuping ZhangHaifan LinZhengqing OuyangPublished in: BMC bioinformatics (2022)
Our results suggest the openness of the 3' UTR promotes the translation efficiency in both mice and zebrafish, with the in vivo structure in 3' UTR more important in mice than in zebrafish. This reveals a novel role of RNA secondary structure on translational regulation.