Comprehensive clinical assessment identifies specific neurocognitive deficits in working-age patients with long-COVID.
David A HoldsworthRebecca ChamleyRob Barker-DaviesOliver O'SullivanPeter LadlowJames L MitchellDominic DewsonDaniel MillsSamantha L J MayMark CranleyCheng XieEdward SellonJoseph MulaeJon NaylorBetty RamanNick P TalbotOliver J RiderAlexander N BennettEdward D NicolPublished in: PloS one (2022)
Despite low rates of residual cardiopulmonary pathology, in this cohort, with low rates of premorbid illness, there is a high burden of symptoms and failure to regain pre-COVID performance 6-months after acute illness. Cognitive assessment identified a specific deficit of the same magnitude as intoxication at the UK drink driving limit or the deterioration expected with 10 years ageing, which appears to contribute significantly to the symptomatology of long-COVID.