Interleaved Propofol-Ketamine Maintains DBS Physiology and Hemodynamic Stability: A Double-Blind Randomized Controlled Trial.

Evgeniya Kornilov Halen Baker ErdmanEilat KahanaShlomo FiremanOmer ZarchiMichal IsraelashviliJohnathan ReinerAmir GlikPenina WeissRony PazHagai BergmanIdit Tamir

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

Ketamine-induced conscious sedation provided high quality microelectrode recordings comparable with awake conditions. Additionally, it seems to allow superior patient satisfaction and hemodynamic stability, while maintaining similar post-operative outcomes. Therefore, it holds promise as a novel alternative anesthetic regimen for DBS. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

deep brain stimulation
patient satisfaction
randomized controlled trial
pain management
study protocol
high glucose
diabetic rats
big data
type diabetes
drug induced
clinical trial
oxidative stress
machine learning
chronic pain
weight loss
skeletal muscle
extracorporeal membrane oxygenation