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An Overview on Topical Administration of Carotenoids and Coenzyme Q10 Loaded in Lipid Nanoparticles.

Luciana de Souza GuedesRenata Miliani MartinezNádia A Bou-ChacraMaria Valéria Robles VelascoCatarina Fialho RosadoAndré Rolim Baby
Published in: Antioxidants (Basel, Switzerland) (2021)
Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are also found in human skin. These bioactive compounds have been the focus of considerable research due to their antioxidant, anti-inflammatory, and photoprotective properties. In this review, the current state of the art in the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to improve their bioavailability, chemical stability, and skin absorption is discussed. Additionally, the main findings are highlighted on the cytotoxic and photoprotective effects of these systems in the skin.
Keyphrases
  • anti inflammatory
  • wound healing
  • soft tissue
  • oxidative stress
  • fatty acid
  • drug delivery
  • cancer therapy