Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.
Lina WirestamHelena EnocssonThomas SkoghLeonid PadyukovAndreas JönsenMurray B UrowitzDafna D GladmanJuanita Romero-DiazSang-Cheol BaePaul R FortinJorge Sanchez-GuerreroAnn E ClarkeSasha BernatskyCaroline GordonJohn G HanlyDaniel WallaceDavid A IsenbergAnisur RahmanJoan MerrillEllen GinzlerGraciela S AlarcónW Winn ChathamMichelle PetriMunther KhamashtaCynthia AranowMeggan MackayMary Anne DooleySusan ManziRosalind Ramsey-GoldmanOla NivedKristjan SteinssonAsad ZomaGuillermo Ruiz-IrastorzaSam LimKen KalunianMurat InancRonald van VollenhovenManuel Ramos-CasalsDiane L KamenSøren JacobsenChristine PeschkenAnca AskanaseThomas StollIan N BruceJonas WetteröChristopher SjöwallPublished in: The Journal of rheumatology (2019)
The performance of OPN to predict development of organ damage was not impressive. However, OPN associated significantly with lupus nephritis and with raised disease activity at enrollment, as well as over time.