Mesenchymal stem cell secretome ameliorates over-expression of soluble fms-like tyrosine kinase-1 (sFlt-1) and fetal growth restriction (FGR) in animal SLE model.

Muhammad Adrianes BachnasGustaaf Albert DekkerAmbar MudigdoBambang PurwantoSri SulistyowatiErry Gumilar DachlanMuhammad Ilham Aldika AkbarAngliana ChouwCynthia Retna SartikaWidjiati Widjiati

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2023)

Administration of secretome lowers sFlt-1 expression in placenta, improves fetal growth, and prevents pregnancy loss in a mouse SLE model.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
systemic lupus erythematosus
poor prognosis
mesenchymal stem cells
disease activity
binding protein
mouse model
umbilical cord