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Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial.

Nadinda A M van der EndeBob RoozenbeekLucas E M SmaggeSven P R LuijtenLeo A M AerdenPetra KraayeveldIdo R van den WijngaardGeert J Lycklama À NijeholtHeleen M den HertogH Zwenneke FlachAlexis C WallaceVictor GurewichGregory J Del ZoppoWilliam J MeurerHester F LingsmaAad van der LugtDiederik W J Dippelnull null
Published in: Trials (2022)
NL7409 (November 26, 2018)/NCT04256473 (February 5, 2020).
Keyphrases
  • double blind
  • placebo controlled
  • open label
  • acute ischemic stroke
  • phase iii
  • pulmonary embolism
  • clinical trial
  • phase ii
  • atrial fibrillation
  • anti inflammatory
  • cross sectional
  • study protocol
  • stem cells
  • cell therapy