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UDiTaS™, a genome editing detection method for indels and genome rearrangements.

Georgia GiannoukosDawn M CiullaEugenio MarcoHayat S AbdulkerimLuis A BarreraAnne BothmerVidya DhanapalSebastian W GloskowskiHariharan JayaramMorgan L MaederMaxwell N SkorTongyao WangVic E MyerChristopher J Wilson
Published in: BMC genomics (2018)
UDiTaS is a robust and streamlined sequencing method useful for measuring small indels as well as structural rearrangements, like translocations, in a single reaction. UDiTaS is especially useful for pre-clinical and clinical application of gene editing to measure on- and off-target editing, large and small.
Keyphrases
  • crispr cas
  • genome editing
  • loop mediated isothermal amplification
  • label free
  • gene expression
  • dna methylation
  • sensitive detection