UDiTaS™, a genome editing detection method for indels and genome rearrangements.
Georgia GiannoukosDawn M CiullaEugenio MarcoHayat S AbdulkerimLuis A BarreraAnne BothmerVidya DhanapalSebastian W GloskowskiHariharan JayaramMorgan L MaederMaxwell N SkorTongyao WangVic E MyerChristopher J WilsonPublished in: BMC genomics (2018)
UDiTaS is a robust and streamlined sequencing method useful for measuring small indels as well as structural rearrangements, like translocations, in a single reaction. UDiTaS is especially useful for pre-clinical and clinical application of gene editing to measure on- and off-target editing, large and small.