Post hoc analysis of a randomised controlled trial: effect of vitamin D supplementation on circulating levels of desmosine in COPD.

Rob Janssen Jef SerréIanthe PiscaerRuben ZaalHenny van DaalCarolien MathyssenPieter ZanenJody M W van den OuwelandWim Janssens

Published in: ERJ open research (2020)

Vitamin D supplementation did not have a significant overall effect on elastin degradation compared to placebo. Contrary to our hypothesis, the intervention decelerated elastin degradation in vitamin D-sufficient COPD patients and not in vitamin D-deficient subjects.

Keyphrases

chronic obstructive pulmonary disease
end stage renal disease
randomized controlled trial
lung function
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
air pollution
placebo controlled
wild type