Association between serum levels of survivin and systemic lupus erythematosus.
Sanaz EbrahimianNadereh RashtchizadehAmir GhorbanihaghjoAida Malek MahdaviMehrzad HajialiloAlireza KhabbaziPublished in: International journal of clinical practice (2021)
Survivin which is an inhibitor of apoptosis upregulation has been reported in human autoimmune diseases including rheumatoid arthritis, psoriasis, juvenile idiopathic arthritis and systemic sclerosis, and mouse models of systemic lupus erythematosus. Survivin in systemic lupus erythematosus is downregulated. However, there is no significant association between serum survivin levels and clinical characteristics of SLE.
Keyphrases
- systemic lupus erythematosus
- disease activity
- juvenile idiopathic arthritis
- systemic sclerosis
- rheumatoid arthritis
- interstitial lung disease
- ankylosing spondylitis
- endothelial cells
- mouse model
- oxidative stress
- poor prognosis
- cell proliferation
- endoplasmic reticulum stress
- signaling pathway
- long non coding rna
- cell cycle arrest
- induced pluripotent stem cells
- atopic dermatitis
- idiopathic pulmonary fibrosis