Electrochemical Assays for the Determination of Antidiabetic Drugs-A Review.
Katarzyna FendrychAnna GórskaJoanna SmajdorPublished in: Micromachines (2023)
This article presents the current state of knowledge regarding electrochemical methods for determining the active substances within drugs that are used in the treatment of type 1 and type 2 diabetes. Electrochemical methods of analysis, due to their sensitivity and easiness, are a great alternative to other, usually more expensive analytical assays. The determination of active substances mentioned in this review is based on oxidation or reduction processes on the surface of the working electrode. A wide variety of working electrodes, often modified with materials such as nanoparticles or conducting polymers, have been used for the highly sensitive analysis of antidiabetic drugs. The presented assays allow us to determine the compounds of interest in various samples, such as pharmaceutical products or different human bodily fluids.
Keyphrases
- molecularly imprinted
- solid phase extraction
- gold nanoparticles
- type diabetes
- high throughput
- label free
- ionic liquid
- endothelial cells
- healthcare
- cardiovascular disease
- drug induced
- electron transfer
- reduced graphene oxide
- insulin resistance
- glycemic control
- liquid chromatography
- metabolic syndrome
- adipose tissue
- tandem mass spectrometry
- induced pluripotent stem cells
- pluripotent stem cells
- replacement therapy