JCI insight

Keyphrases

Publications

volume 9, number 9, 2024

Xizhao Chen, Tiantian Wang, Lei Chen, Yinghua Zhao, Yiyao Deng, Wanjun Shen, Lin Li, Zhong Yin, Chaoran Zhang, Guangyan Cai, Min Zhang, Xiangmei Chen
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression. JCI insight 9 (9) (2024)
Deborah L Cross, Erik D Layton, Krystle Kq Yu, Malisa T Smith, Melissa S Aguilar, Shamin Li, Elise C Wilcox, Aude G Chapuis, Harriet Mayanja-Kizza, Catherine M Stein, W Henry Boom, Thomas R Hawn, Philip Bradley, Evan W Newell, Chetan Seshadri
MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection. JCI insight 9 (9) (2024)
Yoanne D Mouwenda, Simon P Jochems, Vincent Van Unen, Madeleine Eunice Betouke Ongwe, Wouter Aa de Steenhuijsen Piters, Koen A Stam, Marguerite Massinga Loembe, Betty Kim Lee Sim, Meral Esen, Stephen L Hoffman, Peter G Kremsner, Rolf Fendel, Benjamin Mordmüller, Maria Yazdanbakhsh
Immune responses associated with protection induced by chemoattenuated PfSPZ vaccine in malaria-naive Europeans. JCI insight 9 (9) (2024)
Moyinoluwa Taiwo, Emily Huang, Vai Pathak, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David Streem, Craig J McClain, Mack C Mitchell, Bruce A Barton, Gyongyi Szabo, Srinivasan Dasarathy, null null, Esperance A Schaefer, Jay Luther, Le Z Day, Xinshou Ouyang, Arumugam Suyavaran, Wajahat Z Mehal, Jon M Jacobs, Russell P Goodman, Daniel M Rotroff, Laura E Nagy
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis. JCI insight 9 (9) (2024)
Katherine Owens, Shadisadat Esmaeili, Joshua T Schiffer
Heterogeneous SARS-CoV-2 kinetics due to variable timing and intensity of immune responses. JCI insight 9 (9) (2024)
Satvik Mareedu, Nadezhda Fefelova, Cristi L Galindo, Goutham Prakash, Risa Mukai, Junichi Sadoshima, Lai-Hua Xie, Gopal J Babu
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice. JCI insight 9 (9) (2024)
Birol Ay, Sajin Marcus Cyr, Kaitlin Klovdahl, Wen Zhou, Christina M Tognoni, Yorihiro Iwasaki, Eugene P Rhee, Alpaslan Dedeoglu, Petra Simic, Murat Bastepe
Gα11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia. JCI insight 9 (9) (2024)
Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier, David H Wasserman, Benjamin D Humphreys, Jeffrey Koenitzer, Justin Kern, Mark de Caestecker, Toren Finkel, Agnes Fogo, Nidia Messias, Irfan J Lodhi, Leslie S Gewin
Tubular CPT1A deletion minimally affects aging and chronic kidney injury. JCI insight 9 (9) (2024)
Abdulrahman Hm Hassab, David J Hur, Prashanth Vallabhajosyula, George Tellides, Roland Assi
Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis. JCI insight 9 (9) (2024)
Yizheng Jiang, Yu Peng, Qi Tian, Zhe Cheng, Bei Feng, Junping Hu, Lu Xia, Hui Guo, Kun Xia, Liang Zhou, Zhengmao Hu
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2. JCI insight 9 (9) (2024)
Lisa Duvick, W Michael Southern, Kellie A Benzow, Zoe N Burch, Hillary P Handler, Jason S Mitchell, Hannah Kuivinen, Udaya Gadiparthi, Praseuth Yang, Alyssa Soles, Carrie A Sheeler, Orion Rainwater, Shannah Serres, Erin B Lind, Tessa Nichols-Meade, Yun You, Brennon O'Callaghan, Huda Y Zoghbi, Marija Cvetanovic, Vanessa C Wheeler, James M Ervasti, Michael D Koob, Harry T Orr
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease. JCI insight 9 (9) (2024)
Samuel J Virolainen, Latha Satish, Jocelyn M Biagini, Hassan Chaib, Wan Chi Chang, Phillip J Dexheimer, Michael R Dixon, Katelyn Dunn, David Fletcher, Carmy Forney, Marissa Granitto, Matthew S Hestand, Makenna Hurd, Kenneth Kauffman, Lucinda Lawson, Lisa J Martin, Loren Dm Peña, Kieran J Phelan, Molly Shook, Matthew T Weirauch, Gurjit K Khurana Hershey, Leah C Kottyan
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI insight 9 (9) (2024)
Daniel Ledbetter, Romulo Augusto Andrade de Almeida, Xizi Wu, Ariel Naveh, Chirag B Patel, Queena Gonzalez, Thomas H Beckham, Robert North, Laurence Rhines, Jing Li, Amol Ghia, David Aten, Claudio Tatsui, Christopher Alvarez-Breckenridge
Tumor treating fields suppress tumor cell growth and neurologic decline in models of spinal metastases. JCI insight 9 (9) (2024)
Ian Copeland, Edmond Wonkam-Tingang, Monesha Gupta-Malhotra, S Shahrukh Hashmi, Yixing Han, Aarti Jajoo, Nancy J Hall, Paula P Hernandez, Natasha Lie, Dan Liu, Jun Xu, Jill Rosenfeld, Aparna Haldipur, Zelene Desire, Zeynep H Coban-Akdemir, Daryl A Scott, Qing Li, Hsiao-Tuan Chao, Ana M Zaske, James R Lupski, Dianna M Milewicz, Sanjay Shete, Jennifer E Posey, Neil A Hanchard
Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension. JCI insight 9 (9) (2024)
Deborah L Cross, Erik D Layton, Krystle Kq Yu, Malisa T Smith, Melissa S Aguilar, Shamin Li, Elise C Wilcox, Aude G Chapuis, Harriet Mayanja-Kizza, Catherine M Stein, W Henry Boom, Thomas R Hawn, Philip Bradley, Evan W Newell, Chetan Seshadri
MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection. JCI insight 9 (9) (2024)
Yizheng Jiang, Yu Peng, Qi Tian, Zhe Cheng, Bei Feng, Junping Hu, Lu Xia, Hui Guo, Kun Xia, Liang Zhou, Zhengmao Hu
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2. JCI insight 9 (9) (2024)
Ritu Bansal, Monica Torres, Matthew Hunt, Nuoqi Wang, Margarita Chatzopoulou, Mansi Manchanda, Evan P Taddeo, Cynthia Shu, Orian S Shirihai, Etty Bachar-Wikstrom, Jakob D Wikstrom
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion. JCI insight 9 (9) (2024)
Arturo Roca-Rivada, Marcio Do Cruzeiro, Raphaël Gp Denis, Qiang Zhang, Christine Rouault, Yves Rouillé, Jean-Marie Launay, Céline Cruciani-Guglielmacci, Virginie Mattot, Karine Clément, Ralf Jockers, Julie Dam
Whole-body deletion of Endospanin 1 protects from obesity-associated deleterious metabolic alterations. JCI insight 9 (9) (2024)
Kristina M Whately, Nisitha Sengottuvel, Lincy Edatt, Sonal Srivastava, Allison T Woods, Yihsuan S Tsai, Alessandro Porrello, Matthew P Zimmerman, Aaron C Chack, Stuart R Jefferys, Gabriella Yacovone, Dae Joong Kim, Andrew C Dudley, Antonio L Amelio, Chad V Pecot
Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling. JCI insight 9 (9) (2024)
Sabrina N Copsel, Vanessa T Garrido, Henry Barreras, Cameron S Bader, Brent Pfeiffer, Beatriz Mateo-Victoriano, Dietlinde Wolf, Miguel Gallardo, Sophie Paczesny, Krishna V Komanduri, Cara L Benjamin, Alejandro V Villarino, Ashok K Saluja, Robert B Levy
Minnelide suppresses GVHD and enhances survival while maintaining GVT responses. JCI insight 9 (9) (2024)
Deepak Sharma, Darbaz Adnan, Mostafa K Abdel-Reheem, Ron C Anafi, Daniel D Leary, Faraz Bishehsari
Circadian transcriptome of pancreatic adenocarcinoma unravels chronotherapeutic targets. JCI insight 9 (9) (2024)
Moyinoluwa Taiwo, Emily Huang, Vai Pathak, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David Streem, Craig J McClain, Mack C Mitchell, Bruce A Barton, Gyongyi Szabo, Srinivasan Dasarathy, null null, Esperance A Schaefer, Jay Luther, Le Z Day, Xinshou Ouyang, Arumugam Suyavaran, Wajahat Z Mehal, Jon M Jacobs, Russell P Goodman, Daniel M Rotroff, Laura E Nagy
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis. JCI insight 9 (9) (2024)
Julianne Clowry, Daniel J Dempsey, Tracey J Claxton, Aisling M Towell, Mary B Turley, Martin Sutton, Joan A Geoghegan, Sanja Kezic, Ivone Jakasa, Arthur White, Alan D Irvine, Rachel M McLoughlin
Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis. JCI insight 9 (9) (2024)
Joseph M Rocco, Yifan Zhou, Nicholas S Liu, Elizabeth Laidlaw, Frances Galindo, Megan V Anderson, Adam Rupert, Silvia L Lage, Ana M Ortega-Villa, Shiqin Yu, Andrea Lisco, Maura Manion, George S Vassiliou, Cynthia E Dunbar, Irini Sereti
Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes. JCI insight 9 (9) (2024)
Satvik Mareedu, Nadezhda Fefelova, Cristi L Galindo, Goutham Prakash, Risa Mukai, Junichi Sadoshima, Lai-Hua Xie, Gopal J Babu
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice. JCI insight 9 (9) (2024)
Birol Ay, Sajin Marcus Cyr, Kaitlin Klovdahl, Wen Zhou, Christina M Tognoni, Yorihiro Iwasaki, Eugene P Rhee, Alpaslan Dedeoglu, Petra Simic, Murat Bastepe
Gα11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia. JCI insight 9 (9) (2024)
Lisa Duvick, W Michael Southern, Kellie A Benzow, Zoe N Burch, Hillary P Handler, Jason S Mitchell, Hannah Kuivinen, Udaya Gadiparthi, Praseuth Yang, Alyssa Soles, Carrie A Sheeler, Orion Rainwater, Shannah Serres, Erin B Lind, Tessa Nichols-Meade, Yun You, Brennon O'Callaghan, Huda Y Zoghbi, Marija Cvetanovic, Vanessa C Wheeler, James M Ervasti, Michael D Koob, Harry T Orr
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease. JCI insight 9 (9) (2024)
Satvik Mareedu, Nadezhda Fefelova, Cristi L Galindo, Goutham Prakash, Risa Mukai, Junichi Sadoshima, Lai-Hua Xie, Gopal J Babu
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice. JCI insight 9 (9) (2024)
Søren Nielsen, Michael D Jensen
Insulin regulation of regional lipolysis in upper-body obese and lean humans. JCI insight 9 (9) (2024)
Ritu Bansal, Monica Torres, Matthew Hunt, Nuoqi Wang, Margarita Chatzopoulou, Mansi Manchanda, Evan P Taddeo, Cynthia Shu, Orian S Shirihai, Etty Bachar-Wikstrom, Jakob D Wikstrom
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion. JCI insight 9 (9) (2024)
Lisa Duvick, W Michael Southern, Kellie A Benzow, Zoe N Burch, Hillary P Handler, Jason S Mitchell, Hannah Kuivinen, Udaya Gadiparthi, Praseuth Yang, Alyssa Soles, Carrie A Sheeler, Orion Rainwater, Shannah Serres, Erin B Lind, Tessa Nichols-Meade, Yun You, Brennon O'Callaghan, Huda Y Zoghbi, Marija Cvetanovic, Vanessa C Wheeler, James M Ervasti, Michael D Koob, Harry T Orr
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease. JCI insight 9 (9) (2024)
Samuel J Virolainen, Latha Satish, Jocelyn M Biagini, Hassan Chaib, Wan Chi Chang, Phillip J Dexheimer, Michael R Dixon, Katelyn Dunn, David Fletcher, Carmy Forney, Marissa Granitto, Matthew S Hestand, Makenna Hurd, Kenneth Kauffman, Lucinda Lawson, Lisa J Martin, Loren Dm Peña, Kieran J Phelan, Molly Shook, Matthew T Weirauch, Gurjit K Khurana Hershey, Leah C Kottyan
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI insight 9 (9) (2024)
Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier, David H Wasserman, Benjamin D Humphreys, Jeffrey Koenitzer, Justin Kern, Mark de Caestecker, Toren Finkel, Agnes Fogo, Nidia Messias, Irfan J Lodhi, Leslie S Gewin
Tubular CPT1A deletion minimally affects aging and chronic kidney injury. JCI insight 9 (9) (2024)
Samuel J Virolainen, Latha Satish, Jocelyn M Biagini, Hassan Chaib, Wan Chi Chang, Phillip J Dexheimer, Michael R Dixon, Katelyn Dunn, David Fletcher, Carmy Forney, Marissa Granitto, Matthew S Hestand, Makenna Hurd, Kenneth Kauffman, Lucinda Lawson, Lisa J Martin, Loren Dm Peña, Kieran J Phelan, Molly Shook, Matthew T Weirauch, Gurjit K Khurana Hershey, Leah C Kottyan
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI insight 9 (9) (2024)
Søren Nielsen, Michael D Jensen
Insulin regulation of regional lipolysis in upper-body obese and lean humans. JCI insight 9 (9) (2024)
Ian Copeland, Edmond Wonkam-Tingang, Monesha Gupta-Malhotra, S Shahrukh Hashmi, Yixing Han, Aarti Jajoo, Nancy J Hall, Paula P Hernandez, Natasha Lie, Dan Liu, Jun Xu, Jill Rosenfeld, Aparna Haldipur, Zelene Desire, Zeynep H Coban-Akdemir, Daryl A Scott, Qing Li, Hsiao-Tuan Chao, Ana M Zaske, James R Lupski, Dianna M Milewicz, Sanjay Shete, Jennifer E Posey, Neil A Hanchard
Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension. JCI insight 9 (9) (2024)
Satvik Mareedu, Nadezhda Fefelova, Cristi L Galindo, Goutham Prakash, Risa Mukai, Junichi Sadoshima, Lai-Hua Xie, Gopal J Babu
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice. JCI insight 9 (9) (2024)
Arturo Roca-Rivada, Marcio Do Cruzeiro, Raphaël Gp Denis, Qiang Zhang, Christine Rouault, Yves Rouillé, Jean-Marie Launay, Céline Cruciani-Guglielmacci, Virginie Mattot, Karine Clément, Ralf Jockers, Julie Dam
Whole-body deletion of Endospanin 1 protects from obesity-associated deleterious metabolic alterations. JCI insight 9 (9) (2024)
Fredrika Hellgren, Anja Rosdahl, Rodrigo Arcoverde Cerveira, Klara Lenart, Sebastian Ols, Yong-Dae Gwon, Seta Kurt, Anna Maria Delis, Gustav Joas, Magnus Evander, Johan Normark, Clas Ahlm, Mattias Ne Forsell, Sara Cajander, Karin Loré
Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans. JCI insight 9 (9) (2024)
Kristina M Whately, Nisitha Sengottuvel, Lincy Edatt, Sonal Srivastava, Allison T Woods, Yihsuan S Tsai, Alessandro Porrello, Matthew P Zimmerman, Aaron C Chack, Stuart R Jefferys, Gabriella Yacovone, Dae Joong Kim, Andrew C Dudley, Antonio L Amelio, Chad V Pecot
Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling. JCI insight 9 (9) (2024)
Myles H Akabas, Lawrence F Brass
The National MD-PhD Program Outcomes Study: career paths followed by Black and Hispanic graduates. JCI insight 9 (9) (2024)
Joseph M Rocco, Yifan Zhou, Nicholas S Liu, Elizabeth Laidlaw, Frances Galindo, Megan V Anderson, Adam Rupert, Silvia L Lage, Ana M Ortega-Villa, Shiqin Yu, Andrea Lisco, Maura Manion, George S Vassiliou, Cynthia E Dunbar, Irini Sereti
Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes. JCI insight 9 (9) (2024)
Søren Nielsen, Michael D Jensen
Insulin regulation of regional lipolysis in upper-body obese and lean humans. JCI insight 9 (9) (2024)
Ian Copeland, Edmond Wonkam-Tingang, Monesha Gupta-Malhotra, S Shahrukh Hashmi, Yixing Han, Aarti Jajoo, Nancy J Hall, Paula P Hernandez, Natasha Lie, Dan Liu, Jun Xu, Jill Rosenfeld, Aparna Haldipur, Zelene Desire, Zeynep H Coban-Akdemir, Daryl A Scott, Qing Li, Hsiao-Tuan Chao, Ana M Zaske, James R Lupski, Dianna M Milewicz, Sanjay Shete, Jennifer E Posey, Neil A Hanchard
Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension. JCI insight 9 (9) (2024)
Moyinoluwa Taiwo, Emily Huang, Vai Pathak, Annette Bellar, Nicole Welch, Jaividhya Dasarathy, David Streem, Craig J McClain, Mack C Mitchell, Bruce A Barton, Gyongyi Szabo, Srinivasan Dasarathy, null null, Esperance A Schaefer, Jay Luther, Le Z Day, Xinshou Ouyang, Arumugam Suyavaran, Wajahat Z Mehal, Jon M Jacobs, Russell P Goodman, Daniel M Rotroff, Laura E Nagy
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis. JCI insight 9 (9) (2024)
Katherine Owens, Shadisadat Esmaeili, Joshua T Schiffer
Heterogeneous SARS-CoV-2 kinetics due to variable timing and intensity of immune responses. JCI insight 9 (9) (2024)
Xizhao Chen, Tiantian Wang, Lei Chen, Yinghua Zhao, Yiyao Deng, Wanjun Shen, Lin Li, Zhong Yin, Chaoran Zhang, Guangyan Cai, Min Zhang, Xiangmei Chen
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression. JCI insight 9 (9) (2024)
Ritu Bansal, Monica Torres, Matthew Hunt, Nuoqi Wang, Margarita Chatzopoulou, Mansi Manchanda, Evan P Taddeo, Cynthia Shu, Orian S Shirihai, Etty Bachar-Wikstrom, Jakob D Wikstrom
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion. JCI insight 9 (9) (2024)
Birol Ay, Sajin Marcus Cyr, Kaitlin Klovdahl, Wen Zhou, Christina M Tognoni, Yorihiro Iwasaki, Eugene P Rhee, Alpaslan Dedeoglu, Petra Simic, Murat Bastepe
Gα11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia. JCI insight 9 (9) (2024)
Daniel Ledbetter, Romulo Augusto Andrade de Almeida, Xizi Wu, Ariel Naveh, Chirag B Patel, Queena Gonzalez, Thomas H Beckham, Robert North, Laurence Rhines, Jing Li, Amol Ghia, David Aten, Claudio Tatsui, Christopher Alvarez-Breckenridge
Tumor treating fields suppress tumor cell growth and neurologic decline in models of spinal metastases. JCI insight 9 (9) (2024)