Trials

Keyphrases

Publications

volume 24, number 1, 2023

Max Topp, Monika Dlugosz-Danecka, Aleksander B Skotnicki, Galina Salogub, Andreas Viardot, Andreas K Klein, Georg Hess, Christian S Michel, Sebastian Grosicki, Alex Gural, Sylvia E Schwarz, Kerstin Pietzko, Ulrike Gärtner, András Strassz, Leila Alland, Jiri Mayer
Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies. Trials 24 (1) (2023)
Sarah Rae, Jonathon Maguire, Mary Aglipay, Melanie Barwick, Karoon Danavan, Jess Haines, Jennifer Jenkins, Marie Klaassen, Myla E Moretti, Frank Ong, Nav Persaud, Michelle Porepa, Sharon Straus, Erika Tavares, Andrew Willan, Catherine Birken
Randomized controlled trial evaluating a virtual parenting intervention for young children at risk of obesity: study protocol for Parenting Addressing Early Years Intervention with Coaching Visits in Toronto (PARENT) trial. Trials 24 (1) (2023)
Yan Zhang, Guangfeng Ruan, Peng Zheng, Sili Huang, Xiaoni Zhou, Xuelian Liu, Wenjie Hu, Huiting Feng, Yangyang Lin, Juanjuan He, Zhenhai Wei, Jiangshan Zhang, Qing Chang, Xiaomei Wei, Tao Fan, Li Jiang, Changhai Ding
Efficacy and safety of GLucocorticoid injections into InfrapaTellar faT pad in patients with knee ostEoarthRitiS: protocol for the GLITTERS randomized controlled trial. Trials 24 (1) (2023)
Lei Yang, Na Hu, Hong Chang, Di Yang, Yunxia Zuo
Routine administration of neostigmine after recovery of spontaneous breathing versus neuromuscular monitor-guided administration of neostigmine in pediatric patients: a parallel, randomized, controlled study. Trials 24 (1) (2023)
Farveh Yahyapoor, Mahdi Keshani, Alireza Sedaghat, Awat Feizi, Cain C T Clark, Mohammad Bagherniya, Mohammad Safarian, Mohaddeseh Badpeyma, Mohammad Reza Shadmand Foumani Moghadam
The effects of adjunctive treatment with L-carnitine on monitoring laboratory variables in ICU patients: a double-blinded randomized controlled clinical trial. Trials 24 (1) (2023)
Mia S Tackney, Tim Morris, Ian White, Clemence Leyrat, Karla Diaz-Ordaz, Elizabeth Williamson
A comparison of covariate adjustment approaches under model misspecification in individually randomized trials. Trials 24 (1) (2023)
Farveh Yahyapoor, Mahdi Keshani, Alireza Sedaghat, Awat Feizi, Cain C T Clark, Mohammad Bagherniya, Mohammad Safarian, Mohaddeseh Badpeyma, Mohammad Reza Shadmand Foumani Moghadam
The effects of adjunctive treatment with L-carnitine on monitoring laboratory variables in ICU patients: a double-blinded randomized controlled clinical trial. Trials 24 (1) (2023)
Young-Eun Jang, Eun-Young Joo, Ji-Hyun Lee, Eun-Hee Kim, Pyoyoon Kang, Jung-Bin Park, Hee-Soo Kim, Jin-Tae Kim
Two-center randomized controlled trial comparing oral chloral hydrate and intranasal combination of dexmedetomidine and ketamine for procedural sedation in children: study protocol. Trials 24 (1) (2023)
Laura Adubra, Dagmar Alber, Per Ashorn, Ulla Ashorn, Yin Bun Cheung, Elaine Cloutman-Green, Fatoumata Diallo, Camilla Ducker, Riku Elovainio, Yue-Mei Fan, Lily Gates, Gwydion Gruffudd, Tiia Haapaniemi, Fadima Haidara, Lotta Hallamaa, Rikhard Ihamuotila, Nigel Klein, Juho Luoma, Owen Martell, Samba Sow, Taru Vehmasto, null null
Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1-11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial. Trials 24 (1) (2023)
Yan Zhang, Guangfeng Ruan, Peng Zheng, Sili Huang, Xiaoni Zhou, Xuelian Liu, Wenjie Hu, Huiting Feng, Yangyang Lin, Juanjuan He, Zhenhai Wei, Jiangshan Zhang, Qing Chang, Xiaomei Wei, Tao Fan, Li Jiang, Changhai Ding
Efficacy and safety of GLucocorticoid injections into InfrapaTellar faT pad in patients with knee ostEoarthRitiS: protocol for the GLITTERS randomized controlled trial. Trials 24 (1) (2023)
Hao Qin, Guo-Qiang Jing, Wei Tan, Jun Wang, Yi-Nan Yin, Rong-Zhang Chen, Wei Zhang, Jie Li
Comparison of high-flow nasal cannula and conventional oxygen therapy for high-risk patients during bronchoscopy examination: protocol for a randomized controlled trial. Trials 24 (1) (2023)
Yan Zhang, Guangfeng Ruan, Peng Zheng, Sili Huang, Xiaoni Zhou, Xuelian Liu, Wenjie Hu, Huiting Feng, Yangyang Lin, Juanjuan He, Zhenhai Wei, Jiangshan Zhang, Qing Chang, Xiaomei Wei, Tao Fan, Li Jiang, Changhai Ding
Efficacy and safety of GLucocorticoid injections into InfrapaTellar faT pad in patients with knee ostEoarthRitiS: protocol for the GLITTERS randomized controlled trial. Trials 24 (1) (2023)
Fabio Silvio Taccone, Rafael Badenes, Carla Bittencourt Rynkowski, Pierre Bouzat, Anselmo Caricato, Pedro Kurtz, Kirsten Moller, Manuel Quintana Diaz, Mathieu Van Der Jagt, Walter Videtta, Jean-Louis Vincent
TRansfusion strategies in Acute brain INjured patients (TRAIN): a prospective multicenter randomized interventional trial protocol. Trials 24 (1) (2023)
Hai-Yan Chen, Xiao-Yan Meng, Hao Gao, Hui Liu, Hai-Bo Qiu, Jun Lu, Hong-Hao Song
Esketamine-based opioid-free anaesthesia alleviates postoperative nausea and vomiting in patients who underwent laparoscopic surgery: study protocol for a randomized, double-blinded, multicentre trial. Trials 24 (1) (2023)
Sarah T Hawley, Kelley Kidwell, David Zahrieh, Anne McCarthy, Rachel Wills, Aaron Rankin, Timothy Hofer, Selina Chow, Reshma Jagsi, Heather Neuman
Improving patient-centered communication in breast cancer: a study protocol for a multilevel intervention of a shared treatment deliberation system (SharES) within the NCI community oncology research program (NCORP) (Alliance A231901CD). Trials 24 (1) (2023)
Hasitha Tissera, D S Anoja F Dheerasinghe, Neelika Malavige, H Asita de Silva, Amy C Morrison, Thomas W Scott, Robert C Reiner, John P Grieco, Nicole L Achee
A cluster-randomized, placebo-controlled trial to evaluate the efficacy of a spatial repellent (Mosquito Shield™) against Aedes-borne virus infection among children ≥ 4-16 years of age in the Gampaha District, Sri Lanka: study protocol (the AEGIS program). Trials 24 (1) (2023)
Shivam Joshi
Common Clinical Trial Amendments, why they are submitted and how they can be avoided: a mixed methods study on NHS UK Sponsored Research (Amendments Assemble). Trials 24 (1) (2023)
Laura Adubra, Dagmar Alber, Per Ashorn, Ulla Ashorn, Yin Bun Cheung, Elaine Cloutman-Green, Fatoumata Diallo, Camilla Ducker, Riku Elovainio, Yue-Mei Fan, Lily Gates, Gwydion Gruffudd, Tiia Haapaniemi, Fadima Haidara, Lotta Hallamaa, Rikhard Ihamuotila, Nigel Klein, Juho Luoma, Owen Martell, Samba Sow, Taru Vehmasto, null null
Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1-11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial. Trials 24 (1) (2023)
Young-Eun Jang, Eun-Young Joo, Ji-Hyun Lee, Eun-Hee Kim, Pyoyoon Kang, Jung-Bin Park, Hee-Soo Kim, Jin-Tae Kim
Two-center randomized controlled trial comparing oral chloral hydrate and intranasal combination of dexmedetomidine and ketamine for procedural sedation in children: study protocol. Trials 24 (1) (2023)
Max Topp, Monika Dlugosz-Danecka, Aleksander B Skotnicki, Galina Salogub, Andreas Viardot, Andreas K Klein, Georg Hess, Christian S Michel, Sebastian Grosicki, Alex Gural, Sylvia E Schwarz, Kerstin Pietzko, Ulrike Gärtner, András Strassz, Leila Alland, Jiri Mayer
Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies. Trials 24 (1) (2023)
Farveh Yahyapoor, Mahdi Keshani, Alireza Sedaghat, Awat Feizi, Cain C T Clark, Mohammad Bagherniya, Mohammad Safarian, Mohaddeseh Badpeyma, Mohammad Reza Shadmand Foumani Moghadam
The effects of adjunctive treatment with L-carnitine on monitoring laboratory variables in ICU patients: a double-blinded randomized controlled clinical trial. Trials 24 (1) (2023)
Young-Eun Jang, Eun-Young Joo, Ji-Hyun Lee, Eun-Hee Kim, Pyoyoon Kang, Jung-Bin Park, Hee-Soo Kim, Jin-Tae Kim
Two-center randomized controlled trial comparing oral chloral hydrate and intranasal combination of dexmedetomidine and ketamine for procedural sedation in children: study protocol. Trials 24 (1) (2023)
Zeid Badurdeen, Neelakanthi Ratnatunga, Tilak Abeysekera, Abdul W M Wazil, Premil N Rajakrishna, Jalitha P Thinnarachchi, Dulani D Welagedera, Nadeeka Ratnayake, Adambarage P D Alwis, Hemalika Abeysundara, Ranjith Kumarasiri, Richard Taylor, Nishantha Nanayakkara
Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology. Trials 24 (1) (2023)
Laura Adubra, Dagmar Alber, Per Ashorn, Ulla Ashorn, Yin Bun Cheung, Elaine Cloutman-Green, Fatoumata Diallo, Camilla Ducker, Riku Elovainio, Yue-Mei Fan, Lily Gates, Gwydion Gruffudd, Tiia Haapaniemi, Fadima Haidara, Lotta Hallamaa, Rikhard Ihamuotila, Nigel Klein, Juho Luoma, Owen Martell, Samba Sow, Taru Vehmasto, null null
Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1-11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial. Trials 24 (1) (2023)
Max Topp, Monika Dlugosz-Danecka, Aleksander B Skotnicki, Galina Salogub, Andreas Viardot, Andreas K Klein, Georg Hess, Christian S Michel, Sebastian Grosicki, Alex Gural, Sylvia E Schwarz, Kerstin Pietzko, Ulrike Gärtner, András Strassz, Leila Alland, Jiri Mayer
Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies. Trials 24 (1) (2023)
Mia S Tackney, Tim Morris, Ian White, Clemence Leyrat, Karla Diaz-Ordaz, Elizabeth Williamson
A comparison of covariate adjustment approaches under model misspecification in individually randomized trials. Trials 24 (1) (2023)
Lin-Zi Long, Jian-Feng Chu, Hua Qu, Qiao-Ning Yang, Yan Lu, Chang-Geng Fu, Jun Peng, Ke-Ji Chen
Effects of Qingda granule on patients with grade 1 hypertension at low-medium risk: study protocol for a randomized, controlled, double-blind clinical trial. Trials 24 (1) (2023)
Hai-Yan Chen, Xiao-Yan Meng, Hao Gao, Hui Liu, Hai-Bo Qiu, Jun Lu, Hong-Hao Song
Esketamine-based opioid-free anaesthesia alleviates postoperative nausea and vomiting in patients who underwent laparoscopic surgery: study protocol for a randomized, double-blinded, multicentre trial. Trials 24 (1) (2023)
Florence E M de Rijk, Charlotte L van Veldhuisen, Marc G Besselink, Jeanin E van Hooft, Hjalmar C van Santvoort, Erwin J M van Geenen, Cornelis H van Werkhoven, Pieter Jan F de Jonge, Marco J Bruno, Robert C Verdonk, null null
Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial. Trials 24 (1) (2023)
Michelle Sand Beck, Lise Juul, Morten Frydenberg, Lone Overby Fjorback
On Top of Everything: a study protocol for a cluster-randomised controlled trial testing a teacher training programme to teach mindfulness among students in Danish upper secondary schools and schools of health and social care. Trials 24 (1) (2023)
Michelle Sand Beck, Lise Juul, Morten Frydenberg, Lone Overby Fjorback
On Top of Everything: a study protocol for a cluster-randomised controlled trial testing a teacher training programme to teach mindfulness among students in Danish upper secondary schools and schools of health and social care. Trials 24 (1) (2023)
Zoe Marshman, Helen Rodd, Caroline Fairhurst, Jenny Porritt, Bhupinder Dawett, Peter Day, Nicola Innes, Christopher Vernazza, Tim Newton, Sarah Ronaldson, Liz Cross, Jennie Ross, Sarah R Baker, Catherine Hewitt, David Torgerson, Hannah Ainsworth
The CALM trial protocol: a randomised controlled trial of a guided self-help cognitive behavioural therapy intervention to reduce dental anxiety in children. Trials 24 (1) (2023)
Hasitha Tissera, D S Anoja F Dheerasinghe, Neelika Malavige, H Asita de Silva, Amy C Morrison, Thomas W Scott, Robert C Reiner, John P Grieco, Nicole L Achee
A cluster-randomized, placebo-controlled trial to evaluate the efficacy of a spatial repellent (Mosquito Shield™) against Aedes-borne virus infection among children ≥ 4-16 years of age in the Gampaha District, Sri Lanka: study protocol (the AEGIS program). Trials 24 (1) (2023)
Sarah T Hawley, Kelley Kidwell, David Zahrieh, Anne McCarthy, Rachel Wills, Aaron Rankin, Timothy Hofer, Selina Chow, Reshma Jagsi, Heather Neuman
Improving patient-centered communication in breast cancer: a study protocol for a multilevel intervention of a shared treatment deliberation system (SharES) within the NCI community oncology research program (NCORP) (Alliance A231901CD). Trials 24 (1) (2023)
Sarah Rae, Jonathon Maguire, Mary Aglipay, Melanie Barwick, Karoon Danavan, Jess Haines, Jennifer Jenkins, Marie Klaassen, Myla E Moretti, Frank Ong, Nav Persaud, Michelle Porepa, Sharon Straus, Erika Tavares, Andrew Willan, Catherine Birken
Randomized controlled trial evaluating a virtual parenting intervention for young children at risk of obesity: study protocol for Parenting Addressing Early Years Intervention with Coaching Visits in Toronto (PARENT) trial. Trials 24 (1) (2023)
Hao Qin, Guo-Qiang Jing, Wei Tan, Jun Wang, Yi-Nan Yin, Rong-Zhang Chen, Wei Zhang, Jie Li
Comparison of high-flow nasal cannula and conventional oxygen therapy for high-risk patients during bronchoscopy examination: protocol for a randomized controlled trial. Trials 24 (1) (2023)
Zeid Badurdeen, Neelakanthi Ratnatunga, Tilak Abeysekera, Abdul W M Wazil, Premil N Rajakrishna, Jalitha P Thinnarachchi, Dulani D Welagedera, Nadeeka Ratnayake, Adambarage P D Alwis, Hemalika Abeysundara, Ranjith Kumarasiri, Richard Taylor, Nishantha Nanayakkara
Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology. Trials 24 (1) (2023)
Laura Adubra, Dagmar Alber, Per Ashorn, Ulla Ashorn, Yin Bun Cheung, Elaine Cloutman-Green, Fatoumata Diallo, Camilla Ducker, Riku Elovainio, Yue-Mei Fan, Lily Gates, Gwydion Gruffudd, Tiia Haapaniemi, Fadima Haidara, Lotta Hallamaa, Rikhard Ihamuotila, Nigel Klein, Juho Luoma, Owen Martell, Samba Sow, Taru Vehmasto, null null
Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1-11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial. Trials 24 (1) (2023)
Max Topp, Monika Dlugosz-Danecka, Aleksander B Skotnicki, Galina Salogub, Andreas Viardot, Andreas K Klein, Georg Hess, Christian S Michel, Sebastian Grosicki, Alex Gural, Sylvia E Schwarz, Kerstin Pietzko, Ulrike Gärtner, András Strassz, Leila Alland, Jiri Mayer
Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies. Trials 24 (1) (2023)
Gritt Overbeck, Jakob Kragstrup, Mette Gørtz, Ida Scheel Rasmussen, Anette Hauskov Graungaard, Volkert Dirk Siersma, Sarah de Voss, Ruth Kirk Ertmann, Sinead Shahrzad, Clara Lundmark Appel, Philip Wilson
Family wellbeing in general practice: a study protocol for a cluster-randomised trial of the web-based resilience programme on early child development. Trials 24 (1) (2023)
Hasitha Tissera, D S Anoja F Dheerasinghe, Neelika Malavige, H Asita de Silva, Amy C Morrison, Thomas W Scott, Robert C Reiner, John P Grieco, Nicole L Achee
A cluster-randomized, placebo-controlled trial to evaluate the efficacy of a spatial repellent (Mosquito Shield™) against Aedes-borne virus infection among children ≥ 4-16 years of age in the Gampaha District, Sri Lanka: study protocol (the AEGIS program). Trials 24 (1) (2023)
Zoe Marshman, Helen Rodd, Caroline Fairhurst, Jenny Porritt, Bhupinder Dawett, Peter Day, Nicola Innes, Christopher Vernazza, Tim Newton, Sarah Ronaldson, Liz Cross, Jennie Ross, Sarah R Baker, Catherine Hewitt, David Torgerson, Hannah Ainsworth
The CALM trial protocol: a randomised controlled trial of a guided self-help cognitive behavioural therapy intervention to reduce dental anxiety in children. Trials 24 (1) (2023)
Gritt Overbeck, Jakob Kragstrup, Mette Gørtz, Ida Scheel Rasmussen, Anette Hauskov Graungaard, Volkert Dirk Siersma, Sarah de Voss, Ruth Kirk Ertmann, Sinead Shahrzad, Clara Lundmark Appel, Philip Wilson
Family wellbeing in general practice: a study protocol for a cluster-randomised trial of the web-based resilience programme on early child development. Trials 24 (1) (2023)
Young-Eun Jang, Eun-Young Joo, Ji-Hyun Lee, Eun-Hee Kim, Pyoyoon Kang, Jung-Bin Park, Hee-Soo Kim, Jin-Tae Kim
Two-center randomized controlled trial comparing oral chloral hydrate and intranasal combination of dexmedetomidine and ketamine for procedural sedation in children: study protocol. Trials 24 (1) (2023)
Florence E M de Rijk, Charlotte L van Veldhuisen, Marc G Besselink, Jeanin E van Hooft, Hjalmar C van Santvoort, Erwin J M van Geenen, Cornelis H van Werkhoven, Pieter Jan F de Jonge, Marco J Bruno, Robert C Verdonk, null null
Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial. Trials 24 (1) (2023)
Lei Yang, Na Hu, Hong Chang, Di Yang, Yunxia Zuo
Routine administration of neostigmine after recovery of spontaneous breathing versus neuromuscular monitor-guided administration of neostigmine in pediatric patients: a parallel, randomized, controlled study. Trials 24 (1) (2023)
Shivam Joshi
Common Clinical Trial Amendments, why they are submitted and how they can be avoided: a mixed methods study on NHS UK Sponsored Research (Amendments Assemble). Trials 24 (1) (2023)
Gritt Overbeck, Jakob Kragstrup, Mette Gørtz, Ida Scheel Rasmussen, Anette Hauskov Graungaard, Volkert Dirk Siersma, Sarah de Voss, Ruth Kirk Ertmann, Sinead Shahrzad, Clara Lundmark Appel, Philip Wilson
Family wellbeing in general practice: a study protocol for a cluster-randomised trial of the web-based resilience programme on early child development. Trials 24 (1) (2023)
Lin-Zi Long, Jian-Feng Chu, Hua Qu, Qiao-Ning Yang, Yan Lu, Chang-Geng Fu, Jun Peng, Ke-Ji Chen
Effects of Qingda granule on patients with grade 1 hypertension at low-medium risk: study protocol for a randomized, controlled, double-blind clinical trial. Trials 24 (1) (2023)
Lin-Zi Long, Jian-Feng Chu, Hua Qu, Qiao-Ning Yang, Yan Lu, Chang-Geng Fu, Jun Peng, Ke-Ji Chen
Effects of Qingda granule on patients with grade 1 hypertension at low-medium risk: study protocol for a randomized, controlled, double-blind clinical trial. Trials 24 (1) (2023)