Toxicology

Keyphrases

Publications

volume 509, 2024

Huping Huang, Lingyun Mei, Lu Wang, Yijiang Bai, Kelei Gao, Jian Song, Mengzhu Jiang, Yongjia Chen, Shuai Zhang, Bo Pang, Ye He, Xuewen Wu
Ferroptosis contributes to lead-induced cochlear spiral ganglion neurons injury. Toxicology 509 (2024)

volume 508, 2024

Anna Sonnenburg, Benthe van der Lugt, Johannes Rehn, Paul Wittkowski, Karsten Bech, Florian Padberg, Dimitra Eleftheriadou, Todor Dobrikov, Hans Bouwmeester, Carla Mereu, Ferdinand Graf, Carsten Kneuer, Nynke I Kramer, Tilmann Blümmel
Artificial intelligence-based data extraction for next generation risk assessment: Is fine-tuning of a large language model worth the effort? Toxicology 508 (2024)
Qian Xue, Le Zhang, Rui Wang, Jiayunzhu Xu, Chaofan Wang, Shidi Gao, Xin Fang, Chunyang Meng, Rifeng Lu, Li Guo
Hexavalent chromium reduces testosterone levels by impairing lipophagy and disrupting lipid metabolism homeostasis: Based on a metabolomic analysis. Toxicology 508 (2024)
Edvinas Krugly, Edvardas Bagdonas, Jovile Raudoniute, Preethi Ravikumar, Lauryna Bagdoniene, Darius Ciuzas, Tadas Prasauskas, Ruta Aldonyte, Arno C Gutleb, Dainius Martuzevicius
A novel "cells-on-particles" cytotoxicity testing platform in vitro: design, characterization, and validation against engineered nanoparticle aerosol. Toxicology 508 (2024)
Yanis Zekri, Rikke Poulsen, Martin Hansen, Frédéric Flamant, Romain Guyot
Combining transcriptomics and metabolomics to assess neurodevelopmental alteration caused by in utero exposure of mice to three putative thyroid hormone system disruptors. Toxicology 508 (2024)
Siyu Liu, Jianying Li, Wenhao Wang, Yijun Zhang, Shufeng Li, Tiewen Li, Juntao Jiang, Fujun Zhao
Prenatal exposure to dibutyl phthalate contributes to erectile dysfunction in offspring male rats by activating the RhoA/ROCK signalling pathway. Toxicology 508 (2024)
Derya Sağraç, Oğuz Kaan Kırbaş, Dilek Öztürkoğlu, Pınar Akkuş Süt, Pakize Neslihan Taşlı, Fikrettin Şahin
Exploring the protective potential of NRF2 overexpressed neural extracellular vesicles against cisplatin-induced neurotoxicity via NRF2/ARE pathway. Toxicology 508 (2024)
Jilin Liao, Zhenyu Yang, Jinhua Yang, Hailing Lin, Bingxuan Chen, Hongbo Fu, Xiaojie Lin, Binger Lu, Fenfei Gao
Investigating the cardiotoxicity of N-n-butyl haloperidol iodide: Inhibition mechanisms on hERG channels. Toxicology 508 (2024)
Tong Chen, Boqi Zhang, Guitian He, Caomeihui Shen, Nan Wang, Jinxin Zong, Xue Chen, Lu Chen, Chunjin Li, Xu Zhou
Exosomes-mediated retinoic acid disruption: A link between gut microbiota depletion and impaired spermatogenesis. Toxicology 508 (2024)
Xinuo Lai, Peng Fan, Huidan Deng, Guilin Jia, Zhicai Zuo, Yanchun Hu, Ya Wang, Dongjie Cai, Liping Gou, Yiping Wen, Shumin Yu, Suizhong Cao, Liuhong Shen, Junliang Deng, Zhihua Ren
Effects of isochlorogenic acid A on mitochondrial dynamics imbalance and RLR damage in PAM cells induced by combined mycotoxins. Toxicology 508 (2024)
Kelly Louise Thiel, Juliana da Silva, Micaele Wolfarth, Julia Vanini, João Antonio Pêgas Henriques, Iuri Marques de Oliveira, Fernanda Rabaioli da Silva
Assessment of cytotoxic and genotoxic effects of glyphosate-based herbicide on glioblastoma cell lines: Role of p53 in cellular response and network analysis. Toxicology 508 (2024)
Rahul Kumar, Rama R Gullapalli
Evaluating combined effects of chronic, low-dose exposures of cadmium (CLEC) and hyperglycemia on insulin signaling dysfunction in a hepatocellular model. Toxicology 508 (2024)
Edith Sánchez-Jaramillo, Eduardo Sánchez-Islas, Gabriela B Gómez-González, Nashiely Yáñez-Recendis, Samuel Mucio-Ramírez, Fulvio Barbaro, Roberto Toni, Martha León-Olea
Perinatal exposure to Aroclor 1254 disrupts thyrotropin-releasing hormone mRNA expression in the paraventricular nucleus of male and female rats. Toxicology 508 (2024)
Víctor Blanco-Gozalo, Yaremi Quiros, Laura Vicente-Vicente, Alfredo G Casanova, Sandra M Sancho-Martínez, Francisco J López-Hernández
Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats. Toxicology 508 (2024)
Chengzhi Liu, Cheng Zong, Shuang Chen, Jiangliang Chu, Yifan Yang, Yong Pan, Beilei Yuan, Huazhong Zhang
Machine learning-driven QSAR models for predicting the cytotoxicity of five common microplastics. Toxicology 508 (2024)
Qigui Mo, Chenchen Song, Yu Hua, Wei Wang, Aimei Liu
CYP2E1 mediated deoxynivalenol-induced hepatocyte toxicity by regulating ferroptosis. Toxicology 508 (2024)
Yuqin Xu, Zihan He, Zihan Rao, Zihan Li, Yuxin Hu, Zhongwei Zhang, Jianming Zhou, Tong Zhou, Huai Wang
The role of β2-AR/PI3K/AKT pathway in the proliferation, migration and invasion of THLE-2 cells induced by nicotine. Toxicology 508 (2024)
Harm J Heusinkveld, Edwin P Zwart, Angela de Haan, Albert Braeuning, Jimmy Alarcan, Leo T M van der Ven
The zebrafish embryo as a model for chemically-induced steatosis: A case study with three pesticides. Toxicology 508 (2024)
Chen-Yi Weng, Tzu-Ching Chang, Jun-Yang Liou, Ju-Hsin Hsu, Chia-Chi Ho, Salim Arrokhman, Pinpin Lin
Evaluating the embryotoxicity of benzophenone-based photoinitiators in stem cells and zebrafish embryos. Toxicology 508 (2024)
Tao Xu, Yilin Shen, Runmin Guo, Chiheng Luo, Yibo Niu, Zhilong Luo, Zhongxin Zhu, Zehui Wu, Xinyu Zhao, Hao Luo, Yuting Gao
Mutual regulation between histone methyltransferase Suv39h1 and the Wnt/β-catenin signaling pathway promoted cell proliferation and inhibited apoptosis in bone marrow mesenchymal stem cells exposed to hydroquinone. Toxicology 508 (2024)
Yongli Ye, Luyao Tang, Jia-Sheng Wang, Lili Tang, Xiao Ning, Jiadi Sun, Lina Sheng, Xiulan Sun
Unexpected antagonism of deoxynivalenol and enniatins in intestinal toxicity through the Ras/PI3K/AKT signaling pathway. Toxicology 508 (2024)
Pankaj Kumar, Snigdha Singh, Amel Gacem, Krishna Kumar Yadav, Javed Khan Bhutto, Maha Awjan Alreshidi, Manoj Kumar, Anand Kumar, Virendra Kumar Yadav, Sunil Soni, Ramesh Kumar, Maytham T Qasim, Mohd Tariq, Mir Waqas Alam
A review on e-waste contamination, toxicity, and sustainable clean-up approaches for its management. Toxicology 508 (2024)
Wenjuan Chen, Mengning Sun, Yi Sun, Qinglan Yang, Hui Gao, Li Li, Rongrong Fu, Na Dong
Proteasome inhibition induces apoptosis through simultaneous inactivation of MCL-1/BCL-XL by NOXA independent of CHOP and JNK pathways. Toxicology 508 (2024)
Yi Feng, Shao-Qin Tu, Yu-Luan Hou, Yi-Ting Shao, Lin Chen, Zhi-Hui Mai, Yu-Xuan Wang, Jia-Ming Wei, Sai Zhang, Hong Ai, Zheng Chen
Alendronate sodium induces G1 phase arrest and apoptosis in human umbilical vein endothelial cells by inhibiting ROS-mediated ERK1/2 signaling. Toxicology 508 (2024)
Gracen E Collier, Ramon Lavado
An in-depth examination of Per- and Polyfluoroalkyl (PFAS) effects on transporters, with emphasis on the ABC superfamily: A critical review. Toxicology 508 (2024)

volume 507, 2024

Rami M Mosaoa, Mohammed W Al-Rabia, Hani Z Asfour, Nabil A Alhakamy, Rasha A Mansouri, Dina S El-Agamy, Wesam H Abdulaal, Gamal A Mohamed, Sabrin R M Ibrahim, Mahmoud Elshal
Targeting SIRT1/AMPK/Nrf2/NF-кB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury. Toxicology 507 (2024)
Marilène Trancart, Antoine Botta, Christine Le Coz, Nathalie Guatto, André-Guilhem Calas, Anne-Sophie Hanak
How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice? Toxicology 507 (2024)
Qi Zhou, Zhize Ye, Xiaoyu Xu, Yunshan Zhong, Jianchao Luo, Zheyan Zhang, Jing Chen, Zhongxi Chen, Jianping Cai, Xiaodan Zhang, Jianchang Qian
Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib. Toxicology 507 (2024)
Nicholas Pintori, Maria Pina Serra, Antonio Carai, Carla Lobina, Raffaella Isola, Roberta Noli, Gessica Piras, Enrica Spano, Michael H Baumann, Marina Quartu, Maria Antonietta De Luca
Evidence for enduring cardiac and multiorgan toxicity after repeated exposure to the synthetic cannabinoid JWH-018 in male rats. Toxicology 507 (2024)
Marilène Trancart, Antoine Botta, Christine Le Coz, Nathalie Guatto, André-Guilhem Calas, Anne-Sophie Hanak
How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice? Toxicology 507 (2024)
Ruoyun Dong, Li Li, Hongmei Chang, Guanling Song, Sixiu Liu
Study on the mechanisms of defective spermatogenesis induced by TiO 2 NPs based on 3D blood-testis barrier microfluidic chip. Toxicology 507 (2024)
Moon Yi Ko, Heejin Park, Younhee Kim, Euijun Min, Sin-Woo Cha, Byoung-Seok Lee, Sung-Ae Hyun, Minhan Ka
Bisphenol S (BPS) induces glioblastoma progression via regulation of EZH2-mediated PI3K/AKT/mTOR pathway in U87-MG cells. Toxicology 507 (2024)
Gyuri Kim, Hee Joon Yoo, Min Ki Yoo, Ju Hyeong Choi, Kwang-Won Lee
Methylglyoxal-derived hydroimidazolone-1/RAGE axis induces renal oxidative stress and renal fibrosis in vitro and in vivo. Toxicology 507 (2024)
Na Wang, Hong-Qiang Chen, Yong Zeng, Yu Shi, Zhe Zhang, Jiang-Ying Li, Shi-Meng Zhou, Ya-Wen Li, Shuang-Wu Deng, Xue Han, Zi-Yuan Zhou, Mao-Lin Yao, Wen-Bin Liu
Benzo(a)pyrene promotes the malignant progression of malignant-transformed BEAS-2B cells by regulating YTH N6-methyladenosine RNA binding protein 1 to inhibit ferroptosis. Toxicology 507 (2024)
Na Wang, Hong-Qiang Chen, Yong Zeng, Yu Shi, Zhe Zhang, Jiang-Ying Li, Shi-Meng Zhou, Ya-Wen Li, Shuang-Wu Deng, Xue Han, Zi-Yuan Zhou, Mao-Lin Yao, Wen-Bin Liu
Benzo(a)pyrene promotes the malignant progression of malignant-transformed BEAS-2B cells by regulating YTH N6-methyladenosine RNA binding protein 1 to inhibit ferroptosis. Toxicology 507 (2024)
Lixia Du, Hong Liu, Xuan Song, Xiaoqian Feng, Hui Xu, Wei Tang, Jie Yang
Developments in the field of intestinal toxicity and signaling pathways associated with rodent exposure to micro(nano)plastics. Toxicology 507 (2024)
Nicholas Pintori, Maria Pina Serra, Antonio Carai, Carla Lobina, Raffaella Isola, Roberta Noli, Gessica Piras, Enrica Spano, Michael H Baumann, Marina Quartu, Maria Antonietta De Luca
Evidence for enduring cardiac and multiorgan toxicity after repeated exposure to the synthetic cannabinoid JWH-018 in male rats. Toxicology 507 (2024)
Xiaomeng Zhang, Qi Geng, Lin Lin, Lulu Zhang, Changqi Shi, Bin Liu, Lan Yan, Zhiwen Cao, Li Li, Peipei Lu, Yong Tan, Xiaojuan He, Ning Zhao, Li Li, Cheng Lu
Insights gained into the injury mechanism of drug and herb induced liver injury in the hepatic microenvironment. Toxicology 507 (2024)
Yanqiu Yang, Chunpeng Gao, Qiujuan Li, Yong Liu, Jun Cao
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration. Toxicology 507 (2024)
Rami M Mosaoa, Mohammed W Al-Rabia, Hani Z Asfour, Nabil A Alhakamy, Rasha A Mansouri, Dina S El-Agamy, Wesam H Abdulaal, Gamal A Mohamed, Sabrin R M Ibrahim, Mahmoud Elshal
Targeting SIRT1/AMPK/Nrf2/NF-кB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury. Toxicology 507 (2024)
Yanqiu Yang, Chunpeng Gao, Qiujuan Li, Yong Liu, Jun Cao
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration. Toxicology 507 (2024)
Xiaomeng Zhang, Qi Geng, Lin Lin, Lulu Zhang, Changqi Shi, Bin Liu, Lan Yan, Zhiwen Cao, Li Li, Peipei Lu, Yong Tan, Xiaojuan He, Ning Zhao, Li Li, Cheng Lu
Insights gained into the injury mechanism of drug and herb induced liver injury in the hepatic microenvironment. Toxicology 507 (2024)
Qi Zhou, Zhize Ye, Xiaoyu Xu, Yunshan Zhong, Jianchao Luo, Zheyan Zhang, Jing Chen, Zhongxi Chen, Jianping Cai, Xiaodan Zhang, Jianchang Qian
Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib. Toxicology 507 (2024)
Ruoyun Dong, Li Li, Hongmei Chang, Guanling Song, Sixiu Liu
Study on the mechanisms of defective spermatogenesis induced by TiO 2 NPs based on 3D blood-testis barrier microfluidic chip. Toxicology 507 (2024)
Yanqiu Yang, Chunpeng Gao, Qiujuan Li, Yong Liu, Jun Cao
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration. Toxicology 507 (2024)
Gyuri Kim, Hee Joon Yoo, Min Ki Yoo, Ju Hyeong Choi, Kwang-Won Lee
Methylglyoxal-derived hydroimidazolone-1/RAGE axis induces renal oxidative stress and renal fibrosis in vitro and in vivo. Toxicology 507 (2024)
Lixia Du, Hong Liu, Xuan Song, Xiaoqian Feng, Hui Xu, Wei Tang, Jie Yang
Developments in the field of intestinal toxicity and signaling pathways associated with rodent exposure to micro(nano)plastics. Toxicology 507 (2024)

volume 506, 2024

Hiroki Taguchi, Daigo Sumi, Seiichiro Himeno, Hitomi Fujishiro
Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells. Toxicology 506 (2024)
Adam Wood, Catherine Breffa, Caroline Chaine, Richard Cubberley, Matthew Dent, Joachim Eichhorn, Susann Fayyaz, Fabian A Grimm, Jade Houghton, Reiko Kiwamoto, Predrag Kukic, MoungSook Lee, Sophie Malcomber, Suzanne Martin, Beate Nicol, Joe Reynolds, Gordon Riley, Sharon Scott, Colin Smith, Carl Westmoreland, Willemien Wieland, Mesha Williams, Kathryn Wolton, Tristan Zellmann, Steve Gutsell
Next generation risk assessment for occupational chemical safety - A real world example with sodium-2-hydroxyethane sulfonate. Toxicology 506 (2024)
Shujun Huang
Analysis of environmental pollutant Bisphenol F elicited prostate injury targets and underlying mechanisms through network toxicology, molecular docking, and multi-level bioinformatics data integration. Toxicology 506 (2024)