SLAS discovery : advancing life sciences R & D

Keyphrases

Publications

volume 29, number 3, 2024

Mujahed I Mustafa, Ahmed Mohammed
Developing recombinant antibodies by phage display technology to neutralize viral infectious diseases. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Simon C C Lucas, J Henry Blackwell, Sarah H Hewitt, Hannah Semple, Benjamin C Whitehurst, Hua Xu
Covalent hits and where to find them. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Luis M Ortiz Jordan, Virneliz Fernández Vega, Justin Shumate, Adam Peles, Jordan Zeiger, Louis Scampavia, Timothy P Spicer
Protocol for high throughput 3D drug screening of patient derived melanoma and renal cell carcinoma. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Simon C C Lucas, J Henry Blackwell, Sarah H Hewitt, Hannah Semple, Benjamin C Whitehurst, Hua Xu
Covalent hits and where to find them. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Luis M Ortiz Jordan, Virneliz Fernández Vega, Justin Shumate, Adam Peles, Jordan Zeiger, Louis Scampavia, Timothy P Spicer
Protocol for high throughput 3D drug screening of patient derived melanoma and renal cell carcinoma. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Zhi-Bin Tong, Ruili Huang, John Braisted, Pei-Hsuan Chu, Anton Simeonov, David L Gerhold
3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Mujahed I Mustafa, Ahmed Mohammed
Developing recombinant antibodies by phage display technology to neutralize viral infectious diseases. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Nicole L Inniss, Margarita Rzhetskaya, Ted Ling-Hu, Ramon Lorenzo-Redondo, Kelly E Bachta, Karla J F Satchell, Judd F Hultquist
Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Luis M Ortiz Jordan, Virneliz Fernández Vega, Justin Shumate, Adam Peles, Jordan Zeiger, Louis Scampavia, Timothy P Spicer
Protocol for high throughput 3D drug screening of patient derived melanoma and renal cell carcinoma. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Jose Brea, Maria J Varela, Geert A Daudey, Maria I Loza
High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Wenwen Zhou, Baoqing You, Xiaomeng Zhao, Shuyi Si, Yan Li, Jing Zhang
Establishment, optimization and validation of a fluorescence polarization-based high-throughput screening assay targeting cathepsin L inhibitors. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Inês C Ferreira, Estefania Torrejón, Bernardo Abecasis, Bruno M Alexandre, Ricardo A Gomes, Chris Verslype, Jos van Pelt, Ana Barbas, Daniel Simão, Tiago M Bandeiras, Alessio Bortoluzzi, Sofia P Rebelo
Aldehyde Dehydrogenase 2 (ALDH2): A novel sorafenib target in hepatocellular carcinoma unraveled by the proteome-wide cellular thermal shift assay. SLAS discovery : advancing life sciences R & D 29 (3) (2024)
Nicole L Inniss, Margarita Rzhetskaya, Ted Ling-Hu, Ramon Lorenzo-Redondo, Kelly E Bachta, Karla J F Satchell, Judd F Hultquist
Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays. SLAS discovery : advancing life sciences R & D 29 (3) (2024)

volume 29, number 4, 2024

Ha Pham, Meera Kumar, Anibal Ramos Martinez, Mahbbat Ali, Robert G Lowery
Development and validation of a generic methyltransferase enzymatic assay based on an SAH riboswitch. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Taís Bacelar Sacramento de Araújo, Raphael Luís Rocha Nogueira, Leonardo de Oliveira Siquara da Rocha, Iasmin Nogueira Bastos, Rosane Borges Dias, Bruno Solano De Freitas Souza, Daniel William Lambert, Ricardo D Coletta, Viviane Aline Oliveira Silva, Clarissa A Gurgel Rocha
Enhancing scaffold-free spheroid models: 3D cell bioprinting method for metastatic HSC3-Oral squamous carcinoma cell line. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C Koneru, Mei-Chu Lo, Rachel Ngo, Pooja Sharma, Amit Vaish, Xiang Yi, Stephan G Zech, Peter Hodder
Creating a more strategic small molecule biophysical hit characterization workflow. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Ha Pham, Meera Kumar, Anibal Ramos Martinez, Mahbbat Ali, Robert G Lowery
Development and validation of a generic methyltransferase enzymatic assay based on an SAH riboswitch. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Alice Lanne, Catherine Bardelle, Gareth Davies, Antonia Turberville, Hannah Semple, Rachel Moore, Geoffrey A Holdgate
POLARISED views and FRETting about probe modulation assays: Learning from High Throughput Screening. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Elizabeth Elton, Carly Strelez, Nolan Ung, Rachel Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M Mumenthaler
A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Wenyu Wang, Jing Tang, Andrea Zaliani
Outline and background for the EU-OS solubility prediction challenge. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Elizabeth Elton, Carly Strelez, Nolan Ung, Rachel Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M Mumenthaler
A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Wenyu Wang, Jing Tang, Andrea Zaliani
Outline and background for the EU-OS solubility prediction challenge. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Elizabeth Elton, Carly Strelez, Nolan Ung, Rachel Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M Mumenthaler
A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Ha Pham, Meera Kumar, Anibal Ramos Martinez, Mahbbat Ali, Robert G Lowery
Development and validation of a generic methyltransferase enzymatic assay based on an SAH riboswitch. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Elizabeth Elton, Carly Strelez, Nolan Ung, Rachel Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M Mumenthaler
A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C Koneru, Mei-Chu Lo, Rachel Ngo, Pooja Sharma, Amit Vaish, Xiang Yi, Stephan G Zech, Peter Hodder
Creating a more strategic small molecule biophysical hit characterization workflow. SLAS discovery : advancing life sciences R & D 29 (4) (2024)
Alice Lanne, Catherine Bardelle, Gareth Davies, Antonia Turberville, Hannah Semple, Rachel Moore, Geoffrey A Holdgate
POLARISED views and FRETting about probe modulation assays: Learning from High Throughput Screening. SLAS discovery : advancing life sciences R & D 29 (4) (2024)

volume 29, number 5, 2024

Juan Daniel Florez Weidinger, Moritz Pfreundschuh, Diana Zörb, Ada Yee, Stephan Heyse, Felix Bärenz, Stephan Steigele
A robust CETSA data analysis automation workflow for routine screening. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Jason Deng, Svetlana Belyanskaya, Ninad Prabhu, Christopher Arico-Muendel, Hongfeng Deng, Christopher B Phelps, David I Israel, Hongfang Yang, Joseph Boyer, G Joseph Franklin, Jeremy L Yap, Kenneth E Lind, Ching-Hsuan Tsai, Christine Donahue, Jennifer D Summerfield
Profiling cells with DELs: Small molecule fingerprinting of cell surfaces. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Paulina Duhita Anindita, Yuka Otsuka, Simon Lattmann, Khac Huy Ngo, Chong Wai Liew, CongBao Kang, Reuben S Harris, Louis Scampavia, Timothy P Spicer, Dahai Luo
A high-throughput cell-based screening method for Zika virus protease inhibitor discovery. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Lucia Azzollini, Dolores Del Prete, Gernot Wolf, Christoph Klimek, Mattia Saggioro, Fernanda Ricci, Eirini Christodoulaki, Tabea Wiedmer, Alvaro Ingles-Prieto, Giulio Superti-Furga, Lia Scarabottolo
Development of a live cell assay for the zinc transporter ZnT8. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Lucia Azzollini, Dolores Del Prete, Gernot Wolf, Christoph Klimek, Mattia Saggioro, Fernanda Ricci, Eirini Christodoulaki, Tabea Wiedmer, Alvaro Ingles-Prieto, Giulio Superti-Furga, Lia Scarabottolo
Development of a live cell assay for the zinc transporter ZnT8. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Holly R Vickery, Johanna M Virta, Markella Konstantinidou, Michelle R Arkin
Development of a NanoBRET assay for evaluation of 14-3-3σ molecular glues. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Maria Filipa Pinto, Julija Sirina, Nicholas D Holliday, Claire L McWhirter
High-throughput kinetics in drug discovery. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Holly R Vickery, Johanna M Virta, Markella Konstantinidou, Michelle R Arkin
Development of a NanoBRET assay for evaluation of 14-3-3σ molecular glues. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Maria Filipa Pinto, Julija Sirina, Nicholas D Holliday, Claire L McWhirter
High-throughput kinetics in drug discovery. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Anna Adam, Elodie Chenu, Dominique Besson
Compound management in a virtual research organization: The cornerstone of a reliable MMV discovery engine. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N Miranda Nebane, Yohanka Martinez-Gzegozewska, Andrew Reece, Pedro Ruiz, Anna Manuvakhova, Ling Zhai, Brooke Warren, Aliyah Curry, Qinghua Zeng, J Robert Bostwick, Paige N Vinson
A high-throughput response to the SARS-CoV-2 pandemic. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Jason Deng, Svetlana Belyanskaya, Ninad Prabhu, Christopher Arico-Muendel, Hongfeng Deng, Christopher B Phelps, David I Israel, Hongfang Yang, Joseph Boyer, G Joseph Franklin, Jeremy L Yap, Kenneth E Lind, Ching-Hsuan Tsai, Christine Donahue, Jennifer D Summerfield
Profiling cells with DELs: Small molecule fingerprinting of cell surfaces. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Lillie E Bell, Catherine Bardelle, Martin J Packer, Johanna Kastl, Geoffrey A Holdgate, Gareth Davies
Characterisation of high throughput screening outputs for small molecule degrader discovery. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Juan Daniel Florez Weidinger, Moritz Pfreundschuh, Diana Zörb, Ada Yee, Stephan Heyse, Felix Bärenz, Stephan Steigele
A robust CETSA data analysis automation workflow for routine screening. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Anna Adam, Elodie Chenu, Dominique Besson
Compound management in a virtual research organization: The cornerstone of a reliable MMV discovery engine. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Diana Santacruz, Francis O Enane, Katrin Fundel-Clemens, Martin Giner, Gernot Wolf, Svenja Onstein, Christoph Klimek, Zachary Smith, Bhagya Wijayawardena, Coralie Viollet
Corrigendum to "Automation of high-throughput mRNA-seq library preparation: a robust, hands-free and time efficient methodology" [SLAS Discovery, Volume 27 (2022) P140-147/2472-5552]. SLAS discovery : advancing life sciences R & D 29 (5) (2024)
Lillie E Bell, Catherine Bardelle, Martin J Packer, Johanna Kastl, Geoffrey A Holdgate, Gareth Davies
Characterisation of high throughput screening outputs for small molecule degrader discovery. SLAS discovery : advancing life sciences R & D 29 (5) (2024)

volume 29, number 6, 2024

Yuhong Du, Dongxue Wang, Vittorio L Katis, Elizabeth L Zoeller, Min Qui, Allan I Levey, Opher Gileadi, Haian Fu, null null
Development of a time-resolved fluorescence resonance energy transfer ultra-high throughput screening assay targeting SYK and FCER1G interaction. SLAS discovery : advancing life sciences R & D 29 (6) (2024)
Peter Kovar, Paul L Richardson, Alla Korepanova, Gustavo A Afanador, Vladimir Stojkovic, Tao Li, Michael R Schrimpf, Teresa I Ng, David A Degoey, Sujatha M Gopalakrishnan, Jun Chen
Development of a sensitive high-throughput enzymatic assay capable of measuring sub-nanomolar inhibitors of SARS-CoV2 Mpro. SLAS discovery : advancing life sciences R & D 29 (6) (2024)
Saumya Gopalkrishnan
From labs to legislation: The interplay between academic research and political realities. SLAS discovery : advancing life sciences R & D 29 (6) (2024)
Yuka Otsuka, Lizhou Zhang, Huihui Mou, Justin Shumate, Claire E Kitzmiller, Louis Scampavia, Thomas D Bannister, Michael Farzan, Hyeryun Choe, Timothy P Spicer
Simultaneous screening for selective SARS-CoV-2, Lassa, and Machupo virus entry inhibitors. SLAS discovery : advancing life sciences R & D 29 (6) (2024)
Robert Ardecky, Daniela G Dengler, Kaleeckal G Harikumar, Mathew M Abelman, Jiwen Zou, Bryan A Kramer, Santhi Reddy Ganji, Steve Olson, Alina Ly, Nikhil Puvvula, Chen-Ting Ma, Raghuveer Ramachandra, Eduard A Sergienko, Laurence J Miller
Structure-activity relationships of thiadiazole agonists of the human secretin receptor. SLAS discovery : advancing life sciences R & D 29 (6) (2024)
Joanna J Sajkowska, Choi Har Tsang, Paweł Kozielewicz
Application of FRET- and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors. SLAS discovery : advancing life sciences R & D 29 (6) (2024)