Bioorganic & medicinal chemistry letters

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Publications

volume 112, 2024

Ishpriya Sharma, Drashti Daraji, James R Horn, Timothy J Hagen
Inhibitors of Rickettsia prowazekii methionine aminopeptidase 1 identified from the Pandemic Response Box. Bioorganic & medicinal chemistry letters 112 (2024)
Seigo Yumura, Daisuke Kitagawa, Kei Moritsugu, Atsushi Nakayama, Tetsuro Shinada, Masaaki Sawa, Takayoshi Kinoshita
Conserved gatekeeper methionine regulates the binding and access of kinase inhibitors to ATP sites of MAP2K1, 4, and 7: Clues for developing selective inhibitors. Bioorganic & medicinal chemistry letters 112 (2024)
Naina Sehra, Rajesh Parmar, Indresh K Maurya, Vinod Kumar, Kulbhushan Tikoo, Rahul Jain
Synthesis and mechanistic study of Aβ 42 C-terminus domain derived tetrapeptides that inhibit Alzheimer's Aβ-aggregation-induced neurotoxicity. Bioorganic & medicinal chemistry letters 112 (2024)
Minghui Liang, Linyue Liu, Jun Liu, Zechun Yang, Mei Wang, Yong Xie, Yuqing Cai, Peng Xue, Yunfu Chen, Peng Zhan, Haiyong Jia
Design, synthesis and anti-HBV activity study of novel HBV capsid assembly modulators. Bioorganic & medicinal chemistry letters 112 (2024)
Ana Matošević, Marija Bartolić, Nikola Maraković, Antonio Zandona, Rajo Petrić, Dejan Opsenica, Anita Bosak
Synthesis and biological evaluation of novel aminoquinolines with an n-octyl linker: Impact of halogen substituents on C(7) or a terminal amino group on anticholinesterase and BACE1 activity. Bioorganic & medicinal chemistry letters 112 (2024)
Violette Richin, Caroline Bouillot, Sandrine Bouvard, Pierre Courault, Sophie Lancelot, Luc Zimmer, Wael Zeinyeh
[ 18 F]RS-127445 radiosynthesis and evaluation as a 5-HT 2B receptor PET radiotracer in rat brain. Bioorganic & medicinal chemistry letters 112 (2024)
Shengli Zhou, Fuka Nishimura, Kazuhaya Wada, Kaho Fujii, Takeshi Kondo, Kazunori Watanabe, Yoshitane Imai, Takashi Ohtsuki, Mizuki Kitamatsu
Configuration of two cysteine residues in a ring within a stapled Bim peptide affects the secondary structure and apoptotic activity. Bioorganic & medicinal chemistry letters 112 (2024)
Ning Yan, Hong-Yan Liu, Ting-Ting Kong, Zi-Hao Kong, Ling-Yun Li, Xin Ma, Yan-Li Zeng, Mei-Jun Wang, Long-Qian Tang, Cheng-Mei Zhang, Zhao-Peng Liu, Chao Liu
Design, synthesis and biological evaluation of thieno[3,2-c]pyrazol-urea derivatives as potent glycogen synthase kinase 3β inhibitors based on the DFG-out conformation. Bioorganic & medicinal chemistry letters 112 (2024)
Hiroki Makanai, Daisuke Mochizuki, Tatsuya Nishihara, Kazuhito Tanabe
Hoechst modification by strain-promoted azide-alkyne cycloaddition for transport of functional molecules into the cell nucleus. Bioorganic & medicinal chemistry letters 112 (2024)
Yilei Huang, Xinyan Peng, Han Zhang, Min Pan, Xiaojing Su, Gang Li, Qingwei Zhang
Design, synthesis and biological evaluation of novel cyano-cinnamate derivatives as mitochondrial pyruvate carrier inhibitors. Bioorganic & medicinal chemistry letters 112 (2024)
Niklas Heine, Alexander Weber, Alexander Pautsch, Dirk Gottschling, Ingo Uphues, Margit Bauer, Rebecca Ebenhoch, Aniket Magarkar, Bernd Nosse, Jörg Thomas Kley
Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability. Bioorganic & medicinal chemistry letters 112 (2024)
Riya Khandelwal, Mahesh Vasava, R B Abhirami, Manaswini Karsharma
Recent advances in triazole synthesis via click chemistry and their pharmacological applications: A review. Bioorganic & medicinal chemistry letters 112 (2024)

volume 111, 2024

Byeol Ryu, Jorge-Eduardo Ponce-Zea, Van-Hieu Mai, Mina Lee, Sang Hyun Sung, Young Won Chin, Won Keun Oh
Inhibition of protein tyrosine phosphatase 1B by serratane triterpenes from Huperzia serrata and their molecular docking study. Bioorganic & medicinal chemistry letters 111 (2024)
Giovanna Pitasi, Marc Fornt-Suñé, Federica Bucolo, Rosaria Gitto, Salvador Ventura, Laura De Luca
Exploitation of the nitro- and/or 4-Trifluoromethyl-decorated phenyl fragment to develop small inhibitors of Alpha-Syn fibril aggregation. Bioorganic & medicinal chemistry letters 111 (2024)
Kazuya Matsuo, Honoka Ogawa, Shusuke Yamaoka, Tomonori Waku, Akio Kobori
A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorganic & medicinal chemistry letters 111 (2024)
Ivan Krizan, Kiran K Solingapuram Sai, Naresh Damuka, Shannon L Macauley, Bernetta Maria Thurman, Masha Long, Kylie Kavanagh
Exploratory Dual PET imaging of [ 18 F] fluorodeoxyglucose and [ 11 C]acetoacetate in type 2 diabetic nonhuman primates. Bioorganic & medicinal chemistry letters 111 (2024)
Naoki Tanaka, Takeshi Fukuda, Rieko Takano, Koji Sasaki, Takashi Tsuji, Riki Goto, Takeshi Kuribayashi, Kyoji Yamaguchi, Yoichi Niitsu, Ken Ishii, Masami Hashimoto, Shinichi Takahashi, Hisakuni Obayashi
Discovery of DS-1093a: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia. Bioorganic & medicinal chemistry letters 111 (2024)
Jonathan L Chen, Amirhossein Taghavi, Alexander J Frank, Matthew A Fountain, Shruti Choudhary, Soma Roy, Jessica L Childs-Disney, Matthew D Disney
NMR structures of small molecules bound to a model of a CUG RNA repeat expansion. Bioorganic & medicinal chemistry letters 111 (2024)
Kazuya Matsuo, Honoka Ogawa, Shusuke Yamaoka, Tomonori Waku, Akio Kobori
A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorganic & medicinal chemistry letters 111 (2024)
Giovanna Pitasi, Marc Fornt-Suñé, Federica Bucolo, Rosaria Gitto, Salvador Ventura, Laura De Luca
Exploitation of the nitro- and/or 4-Trifluoromethyl-decorated phenyl fragment to develop small inhibitors of Alpha-Syn fibril aggregation. Bioorganic & medicinal chemistry letters 111 (2024)
Naoki Tanaka, Takeshi Fukuda, Rieko Takano, Koji Sasaki, Takashi Tsuji, Riki Goto, Takeshi Kuribayashi, Kyoji Yamaguchi, Yoichi Niitsu, Ken Ishii, Masami Hashimoto, Shinichi Takahashi, Hisakuni Obayashi
Discovery of DS-1093a: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia. Bioorganic & medicinal chemistry letters 111 (2024)
Xinhang Zhang, Yashu Li, Yuchen Chen, Ziqi Liu, Zijin Li, Ziyin Wang, Yu Wang, Mingzhe Liu
Design and synthesis of dual functional NBD-fluorophore-incorporated naphthalene diimide derivatives as G-quadruplex ligands. Bioorganic & medicinal chemistry letters 111 (2024)
Dan Luo, Ronghua Luo, Weilin Wang, Rui Deng, Shirui Wang, Xinyu Ma, Chunlan Pu, Yuanyuan Liu, Hongjia Zhang, Su Yu, Qing Huang, Liumeng Yang, Yu Tong, Yongtang Zheng, Rui Li
Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1. Bioorganic & medicinal chemistry letters 111 (2024)
Jigar Desai, Bhaumin Patel, Nandini Panchal, Archana Gite, Brijesh Darji, Kasinath Viswanathan, Jinal Trivedi, Purvi Vyas, Vishwanath Pawar, Poonam Giri, Sachchidanand S, Rajiv Sharma, Mukul Jain, Pravin Iyer, Sanjay Kumar
Discovery of aminopiperidine based potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity. Bioorganic & medicinal chemistry letters 111 (2024)
Kyler Pugh, Hao Xu, Brian S J Blagg
Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorganic & medicinal chemistry letters 111 (2024)
Kazuya Matsuo, Honoka Ogawa, Shusuke Yamaoka, Tomonori Waku, Akio Kobori
A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorganic & medicinal chemistry letters 111 (2024)
Dan Luo, Ronghua Luo, Weilin Wang, Rui Deng, Shirui Wang, Xinyu Ma, Chunlan Pu, Yuanyuan Liu, Hongjia Zhang, Su Yu, Qing Huang, Liumeng Yang, Yu Tong, Yongtang Zheng, Rui Li
Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1. Bioorganic & medicinal chemistry letters 111 (2024)
Jonathan L Chen, Amirhossein Taghavi, Alexander J Frank, Matthew A Fountain, Shruti Choudhary, Soma Roy, Jessica L Childs-Disney, Matthew D Disney
NMR structures of small molecules bound to a model of a CUG RNA repeat expansion. Bioorganic & medicinal chemistry letters 111 (2024)
Ivan Krizan, Kiran K Solingapuram Sai, Naresh Damuka, Shannon L Macauley, Bernetta Maria Thurman, Masha Long, Kylie Kavanagh
Exploratory Dual PET imaging of [ 18 F] fluorodeoxyglucose and [ 11 C]acetoacetate in type 2 diabetic nonhuman primates. Bioorganic & medicinal chemistry letters 111 (2024)
Jigar Desai, Bhaumin Patel, Nandini Panchal, Archana Gite, Brijesh Darji, Kasinath Viswanathan, Jinal Trivedi, Purvi Vyas, Vishwanath Pawar, Poonam Giri, Sachchidanand S, Rajiv Sharma, Mukul Jain, Pravin Iyer, Sanjay Kumar
Discovery of aminopiperidine based potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity. Bioorganic & medicinal chemistry letters 111 (2024)
Kyler Pugh, Hao Xu, Brian S J Blagg
Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorganic & medicinal chemistry letters 111 (2024)
Mélanie Fonte, Catarina Rôla, Sofia Santana, Miguel Prudêncio, Joana Almeida, Ricardo Ferraz, Cristina Prudêncio, Cátia Teixeira, Paula Gomes
Repurposing antiplasmodial leads for cancer: Exploring the antiproliferative effects of N-cinnamoyl-aminoacridines. Bioorganic & medicinal chemistry letters 111 (2024)
Xiu-Jun Wang, Yue Qiao, Zi-Rui Jiang, Jing-Liang He, Bing-Yan Wang, Jia-Rui Wan, Jing Ji, Bin Liu
Design, synthesis, and evaluation of benzodioxolane compounds for antitumor activity. Bioorganic & medicinal chemistry letters 111 (2024)
Ivan Krizan, Kiran K Solingapuram Sai, Naresh Damuka, Shannon L Macauley, Bernetta Maria Thurman, Masha Long, Kylie Kavanagh
Exploratory Dual PET imaging of [ 18 F] fluorodeoxyglucose and [ 11 C]acetoacetate in type 2 diabetic nonhuman primates. Bioorganic & medicinal chemistry letters 111 (2024)
Dan Luo, Ronghua Luo, Weilin Wang, Rui Deng, Shirui Wang, Xinyu Ma, Chunlan Pu, Yuanyuan Liu, Hongjia Zhang, Su Yu, Qing Huang, Liumeng Yang, Yu Tong, Yongtang Zheng, Rui Li
Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1. Bioorganic & medicinal chemistry letters 111 (2024)
Byeol Ryu, Jorge-Eduardo Ponce-Zea, Van-Hieu Mai, Mina Lee, Sang Hyun Sung, Young Won Chin, Won Keun Oh
Inhibition of protein tyrosine phosphatase 1B by serratane triterpenes from Huperzia serrata and their molecular docking study. Bioorganic & medicinal chemistry letters 111 (2024)
Mélanie Fonte, Catarina Rôla, Sofia Santana, Miguel Prudêncio, Joana Almeida, Ricardo Ferraz, Cristina Prudêncio, Cátia Teixeira, Paula Gomes
Repurposing antiplasmodial leads for cancer: Exploring the antiproliferative effects of N-cinnamoyl-aminoacridines. Bioorganic & medicinal chemistry letters 111 (2024)
Uma Agarwal, Saroj Verma, Rajiv K Tonk
Chromenone: An emerging scaffold in anti-Alzheimer drug discovery. Bioorganic & medicinal chemistry letters 111 (2024)
Ivan Krizan, Kiran K Solingapuram Sai, Naresh Damuka, Shannon L Macauley, Bernetta Maria Thurman, Masha Long, Kylie Kavanagh
Exploratory Dual PET imaging of [ 18 F] fluorodeoxyglucose and [ 11 C]acetoacetate in type 2 diabetic nonhuman primates. Bioorganic & medicinal chemistry letters 111 (2024)
Toshiyuki Akiyama, Brian A Johns, Yoshiyuki Taoda, Hiroshi Yoshida, Teruhiko Taishi, Takashi Kawasuji, Hitoshi Murai, Tomokazu Yoshinaga, Akihiko Sato, Takahiro Seki, Mikiko Koyama, Shigeru Miki, Shinobu Kawauchi-Miki, Akemi Kagitani-Suyama, Tamio Fujiwara
Molecular design and evaluation of aza-polycyclic carbamoyl pyridones as HIV-1 integrase strand transfer inhibitors. Bioorganic & medicinal chemistry letters 111 (2024)
Mélanie Fonte, Catarina Rôla, Sofia Santana, Miguel Prudêncio, Joana Almeida, Ricardo Ferraz, Cristina Prudêncio, Cátia Teixeira, Paula Gomes
Repurposing antiplasmodial leads for cancer: Exploring the antiproliferative effects of N-cinnamoyl-aminoacridines. Bioorganic & medicinal chemistry letters 111 (2024)
Byeol Ryu, Jorge-Eduardo Ponce-Zea, Van-Hieu Mai, Mina Lee, Sang Hyun Sung, Young Won Chin, Won Keun Oh
Inhibition of protein tyrosine phosphatase 1B by serratane triterpenes from Huperzia serrata and their molecular docking study. Bioorganic & medicinal chemistry letters 111 (2024)
Xiu-Jun Wang, Yue Qiao, Zi-Rui Jiang, Jing-Liang He, Bing-Yan Wang, Jia-Rui Wan, Jing Ji, Bin Liu
Design, synthesis, and evaluation of benzodioxolane compounds for antitumor activity. Bioorganic & medicinal chemistry letters 111 (2024)
Uma Agarwal, Saroj Verma, Rajiv K Tonk
Chromenone: An emerging scaffold in anti-Alzheimer drug discovery. Bioorganic & medicinal chemistry letters 111 (2024)
Jigar Desai, Bhaumin Patel, Nandini Panchal, Archana Gite, Brijesh Darji, Kasinath Viswanathan, Jinal Trivedi, Purvi Vyas, Vishwanath Pawar, Poonam Giri, Sachchidanand S, Rajiv Sharma, Mukul Jain, Pravin Iyer, Sanjay Kumar
Discovery of aminopiperidine based potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity. Bioorganic & medicinal chemistry letters 111 (2024)
Xinhang Zhang, Yashu Li, Yuchen Chen, Ziqi Liu, Zijin Li, Ziyin Wang, Yu Wang, Mingzhe Liu
Design and synthesis of dual functional NBD-fluorophore-incorporated naphthalene diimide derivatives as G-quadruplex ligands. Bioorganic & medicinal chemistry letters 111 (2024)
Giovanna Pitasi, Marc Fornt-Suñé, Federica Bucolo, Rosaria Gitto, Salvador Ventura, Laura De Luca
Exploitation of the nitro- and/or 4-Trifluoromethyl-decorated phenyl fragment to develop small inhibitors of Alpha-Syn fibril aggregation. Bioorganic & medicinal chemistry letters 111 (2024)
Ivan Krizan, Kiran K Solingapuram Sai, Naresh Damuka, Shannon L Macauley, Bernetta Maria Thurman, Masha Long, Kylie Kavanagh
Exploratory Dual PET imaging of [ 18 F] fluorodeoxyglucose and [ 11 C]acetoacetate in type 2 diabetic nonhuman primates. Bioorganic & medicinal chemistry letters 111 (2024)
Kyler Pugh, Hao Xu, Brian S J Blagg
Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorganic & medicinal chemistry letters 111 (2024)
Naoki Tanaka, Takeshi Fukuda, Rieko Takano, Koji Sasaki, Takashi Tsuji, Riki Goto, Takeshi Kuribayashi, Kyoji Yamaguchi, Yoichi Niitsu, Ken Ishii, Masami Hashimoto, Shinichi Takahashi, Hisakuni Obayashi
Discovery of DS-1093a: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia. Bioorganic & medicinal chemistry letters 111 (2024)