Adam V Patterson

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 13

Top Venues

International journal of molecular sciences

Cancer gene therapy

Pharmaceuticals (Basel, Switzerland)

Molecules (Basel, Switzerland)

University of Auckland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Auckland

New Zealand

Associate Professor :: School of Medical Sciences

Publications

Abigail V Sharrock, Jeff S Mumm, Elsie M Williams, Narimantas Čėnas, Jeff B Smaill, Adam V Patterson, David F Ackerley, Gintautas Bagdžiūnas, Vickery L Arcus
Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623. International journal of molecular sciences 25 (12) (2024)
Abigail V Sharrock, Jeff S Mumm, Elsie M Williams, Narimantas Čėnas, Jeff B Smaill, Adam V Patterson, David F Ackerley, Gintautas Bagdžiūnas, Vickery L Arcus
Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623. International journal of molecular sciences 25 (12) (2024)
Abigail V Sharrock, Jeff S Mumm, Elsie M Williams, Narimantas Čėnas, Jeff B Smaill, Adam V Patterson, David F Ackerley, Gintautas Bagdžiūnas, Vickery L Arcus
Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623. International journal of molecular sciences 25 (12) (2024)
Amir Ashoorzadeh, Alexandra M Mowday, Christopher P Guise, Shevan Silva, Matthew R Bull, Maria R Abbattista, Janine N Copp, Elsie M Williams, David F Ackerley, Adam V Patterson, Jeff B Smaill
Interrogation of the Structure-Activity Relationship of a Lipophilic Nitroaromatic Prodrug Series Designed for Cancer Gene Therapy Applications. Pharmaceuticals (Basel, Switzerland) 15 (2) (2022)
Alexander M A van der Wiel, Victoria Jackson-Patel, Raymon Niemans, Ala Yaromina, Emily Liu, Damiënne Marcus, Alexandra M Mowday, Natasja G Lieuwes, Rianne Biemans, Xiaojing Lin, Zhe Fu, Sisira Kumara, Arthur Jochems, Amir Ashoorzadeh, Robert F Anderson, Kevin O Hicks, Matthew R Bull, Maria R Abbattista, Christopher P Guise, Sofie Deschoemaeker, Sophie Thiolloy, Arne Heyerick, Morwena J Solivio, Silvia Balbo, Jeff B Smaill, Jan Theys, Ludwig J Dubois, Adam V Patterson, Philippe Lambin
Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506. Molecular cancer therapeutics 20 (12) (2021)
Alexandra M Mowday, Ludwig J Dubois, Aleksandra M Kubiak, Jasmine V E Chan-Hyams, Christopher P Guise, Amir Ashoorzadeh, Philippe Lambin, David F Ackerley, Jeff B Smaill, Nigel Peter Minton, Jan Theys, Adam V Patterson
Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours. Cancer gene therapy (2021)
Maria R Abbattista, Amir Ashoorzadeh, Christopher P Guise, Alexandra M Mowday, Rituparna Mittra, Shevan Silva, Kevin O Hicks, Matthew R Bull, Victoria Jackson-Patel, Xiaojing Lin, Gareth A Prosser, Neil K Lambie, Gabi U Dachs, David F Ackerley, Jeff B Smaill, Adam V Patterson
Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3. Pharmaceuticals (Basel, Switzerland) 14 (12) (2021)
Dean C Singleton, Alexandra M Mowday, Chris P Guise, Sophie P Syddall, Sally Y Bai, Dan Li, Amir Ashoorzadeh, Jeff B Smaill, William R Wilson, Adam V Patterson
Bioreductive prodrug PR-104 improves the tumour distribution and titre of the nitroreductase-armed oncolytic adenovirus ONYX-411NTR leading to therapeutic benefit. Cancer gene therapy (2021)
Zhe Fu, Alexandra M Mowday, Jeff B Smaill, Ian F Hermans, Adam V Patterson
Tumour Hypoxia-Mediated Immunosuppression: Mechanisms and Therapeutic Approaches to Improve Cancer Immunotherapy. Cells 10 (5) (2021)
Ziad Omran, Chris P Guise, Linwei Chen, Cyril Rauch, Ashraf N Abdalla, Omeima Abdullah, Ikhlas A Sindi, Peter M Fischer, Jeff B Smaill, Adam V Patterson, Yuxiu Liu, Qingmin Wang
Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents. Molecules (Basel, Switzerland) 26 (11) (2021)
Chris P Guise, Maria R Abbattista, Robert F Anderson, Dan Li, Rana Taghipouran, Angela Tsai, Su Jung Lee, Jeff B Smaill, William Alexander Denny, Michael P Hay, William R Wilson, Kevin O Hicks, Adam V Patterson
Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity. Molecules (Basel, Switzerland) 25 (21) (2020)
Adriana Estrada-Bernal, Anh T Le, Andrea E Doak, Vijaya G Tirunagaru, Shevan Silva, Matthew R Bull, Jeff B Smaill, Adam V Patterson, Chul Kim, Stephen V Liu, Robert C Doebele
Tarloxotinib Is a Hypoxia-Activated Pan-HER Kinase Inhibitor Active Against a Broad Range of HER-Family Oncogenes. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (5) (2020)
Maria Kalyukina, Yuliana Yosaatmadja, Martin J Middleditch, Adam V Patterson, Jeff B Smaill, Christopher J Squire
TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure. ChemMedChem 14 (4) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Adam V Patterson