William Alexander Denny (William Denny, William A Denny)

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 17

Top Topics

Mycobacterium Tuberculosis

Acinetobacter Baumannii

Molecular Docking

Top Venues

Molecules (Basel, Switzerland)

Journal of medicinal chemistry

Pharmaceuticals (Basel, Switzerland)

Oncology and therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Peter Jaein Choi, Petr Tomek, Moana Tercel, Jóhannes Reynisson, Thomas In Hyeup Park, Elizabeth Alexandra Cooper, William Alexander Denny, Jiney Jose, Euphemia Y Leung
Conjugation of Palbociclib with MHI-148 Has an Increased Cytotoxic Effect for Breast Cancer Cells and an Altered Mechanism of Action. Molecules (Basel, Switzerland) 27 (3) (2022)
Guilherme Felipe Dos Santos Fernandes, Andrew M Thompson, Daniele Castagnolo, William Alexander Denny, Jean Leandro Dos Santos
Tuberculosis Drug Discovery: Challenges and New Horizons. Journal of medicinal chemistry 65 (11) (2022)
William Alexander Denny
Nitroaromatic Hypoxia-Activated Prodrugs for Cancer Therapy. Pharmaceuticals (Basel, Switzerland) 15 (2) (2022)
Hamish S Sutherland, Peter Jaein Choi, Guo-Liang Lu, Anna C Giddens, Amy S T Tong, Scott G Franzblau, Christopher B Cooper, Brian D Palmer, William Alexander Denny
Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl- N -(Pyridin-2-ylmethyl)Pyrazolo[1,5- a ]Pyrimidin-7-Amines. Pharmaceuticals (Basel, Switzerland) 15 (9) (2022)
Dennis C Liotta, James C Barrow, Kelly Chibale, Maria Laura Bolognesi, Stuart J Conway, William Alexander Denny, Ke Ding, Stefan A Laufer, Luhua Lai, Hong Liu, Nouri Neamati, Takayoshi Suzuki, Nicholas A Meanwell, Wendy B Young
Simplifying Submission Requirements for the Journal of Medicinal Chemistry. Journal of medicinal chemistry 64 (12) (2021)
Euphemia Y Leung, Jinal Patel, Jennifer A Hollywood, Ayesha Zafar, Petr Tomek, David Barker, Lisa Ivy Pilkington, Michelle van Rensburg, Ries J Langley, Nuala Ann Helsby, Christopher J Squire, Bruce C Baguley, William Alexander Denny, Jóhannes Reynisson, Ivanhoe K H Leung
Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs. Oncology and therapy 9 (2) (2021)
William Alexander Denny, Jack U Flanagan
Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation. Biomolecules 11 (11) (2021)
William Alexander Denny
Inhibitors of F1F0-ATP synthase enzymes for the treatment of tuberculosis and cancer. Future medicinal chemistry 13 (10) (2021)
Zhijun Zhuang, Dawei Wan, Jun Ding, Shijie He, Qian Zhang, Xiaomei Wang, Ying Yuan, Yu Lu, Charles Z Ding, Anthony Simon Lynch, Anna M Upton, Christopher B Cooper, William Alexander Denny, Zhenkun Ma
Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria. Molecules (Basel, Switzerland) 25 (10) (2020)
Peter J Choi, Thomas I H Park, Elizabeth Cooper, Mike Dragunow, William Alexander Denny, Jiney Jose
Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope. Bioconjugate chemistry 31 (7) (2020)
Peter Jaein Choi, Daniel Conole, Hamish S Sutherland, Adrian Blaser, Amy S T Tong, Christopher B Cooper, Anna M Upton, Brian D Palmer, William Alexander Denny
Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876-A Less Toxic and More Potent Analogue of Bedaquiline. Molecules (Basel, Switzerland) 25 (6) (2020)
Ivaylo V Dimitrov, Martyn G Harvey, Logan J Voss, James W Sleigh, Michael J Bickerdike, William Alexander Denny
Structure-Activity Relationships for the Anaesthetic and Analgaesic Properties of Aromatic Ring-Substituted Ketamine Esters. Molecules (Basel, Switzerland) 25 (12) (2020)
Chris P Guise, Maria R Abbattista, Robert F Anderson, Dan Li, Rana Taghipouran, Angela Tsai, Su Jung Lee, Jeff B Smaill, William Alexander Denny, Michael P Hay, William R Wilson, Kevin O Hicks, Adam V Patterson
Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity. Molecules (Basel, Switzerland) 25 (21) (2020)
Vijayalekshmi Sarojini, Alan J Cameron, Kyriakos G Varnava, William Alexander Denny, Gangadhar J Sanjayan
Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function. Chemical reviews 119 (17) (2019)
Julie A Spicer, Christian K Miller, Patrick D O'Connor, Jiney Jose, Anna C Giddens, Jagdish K Jaiswal, Stephen M F Jamieson, Matthew R Bull, William Alexander Denny, Hedieh Akhlaghi, Joseph A Trapani, Geoff R Hill, Karshing Chang, Kate H Gartlan
Inhibition of the Cytolytic Protein Perforin Prevents Rejection of Transplanted Bone Marrow Stem Cells in Vivo. Journal of medicinal chemistry 63 (5) (2019)
Andrew M Thompson, Patrick D O'Connor, Andrew J Marshall, Adrian Blaser, Vanessa Yardley, Louis Maes, Suman Gupta, Delphine Launay, Stephanie Braillard, Eric Chatelain, Baojie Wan, Scott G Franzblau, Zhenkun Ma, Christopher B Cooper, William Alexander Denny
Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis. Journal of medicinal chemistry 61 (6) (2018)
Jessica J Field, A Jonathan Singh, Saptarshi Sinha, Matthew R Rowe, William Alexander Denny, Darby G Brooke, John Holmes Miller
Synthesis and Microtubule-Destabilizing Activity of N-Cyclopropyl-4-((3,4-dihydroquinolin-1(2H)-yl)sulfonyl)benzamide and its Analogs. Chemistry, an Asian journal 14 (8) (2018)