Alberto Villanueva

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 20

Top Topics

Liver Metastases

Top Venues

Nature communications

Cancer discovery

Cell death discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Valentina Tonelotto, Marcel Costa-Garcia, Eve O'Reilly, Kaelin Francis Smith, Kayleigh Slater, Eugene T Dillon, Marzia Pendino, Catherine Higgins, Paola Sist, Rosa Bosch, Sabina Passamonti, Josep M Piulats, Alberto Villanueva, Federica Tramer, Luca Vanella, Michelle Carey, Breandán N Kennedy
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature. Cell death discovery 10 (1) (2024)
Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M Fernandes Neto, Frank van Gemert, Soufiane M C Mourragui, Chrysa Papagianni, Hendrik J Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H S Wilms, Marcelo Santos da Silva, Robin A Jansen, Antonio Mulero-Sanchez, Elke Malzer, August Vidal Bel, Cristina Santos, Ramón Salazar, Rosangela A M Wailemann, Thompson E P Torres, Giulia De Conti, Jonne A Raaijmakers, Petur Snaebjornsson, Sheng-Xian Yuan, Wenxin Qin, John S Kovach, Hugo Aguirre Armelin, Hein Te Riele, Alexander van Oudernaarden, Haojie Jin, Roderick L Beijersbergen, Alberto Villanueva, René H Medema, René Bernards
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy. Cancer discovery 14 (7) (2024)
Valentina Tonelotto, Marcel Costa-Garcia, Eve O'Reilly, Kaelin Francis Smith, Kayleigh Slater, Eugene T Dillon, Marzia Pendino, Catherine Higgins, Paola Sist, Rosa Bosch, Sabina Passamonti, Josep M Piulats, Alberto Villanueva, Federica Tramer, Luca Vanella, Michelle Carey, Breandán N Kennedy
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature. Cell death discovery 10 (1) (2024)
Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M Fernandes Neto, Frank van Gemert, Soufiane M C Mourragui, Chrysa Papagianni, Hendrik J Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H S Wilms, Marcelo Santos da Silva, Robin A Jansen, Antonio Mulero-Sanchez, Elke Malzer, August Vidal Bel, Cristina Santos, Ramón Salazar, Rosangela A M Wailemann, Thompson E P Torres, Giulia De Conti, Jonne A Raaijmakers, Petur Snaebjornsson, Sheng-Xian Yuan, Wenxin Qin, John S Kovach, Hugo Aguirre Armelin, Hein Te Riele, Alexander van Oudernaarden, Haojie Jin, Roderick L Beijersbergen, Alberto Villanueva, René H Medema, René Bernards
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy. Cancer discovery 14 (7) (2024)
Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M Fernandes Neto, Frank van Gemert, Soufiane M C Mourragui, Chrysa Papagianni, Hendrik J Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H S Wilms, Marcelo Santos da Silva, Robin A Jansen, Antonio Mulero-Sanchez, Elke Malzer, August Vidal Bel, Cristina Santos, Ramón Salazar, Rosangela A M Wailemann, Thompson E P Torres, Giulia De Conti, Jonne A Raaijmakers, Petur Snaebjornsson, Sheng-Xian Yuan, Wenxin Qin, John S Kovach, Hugo Aguirre Armelin, Hein Te Riele, Alexander van Oudernaarden, Haojie Jin, Roderick L Beijersbergen, Alberto Villanueva, René H Medema, René Bernards
Paradoxical activation of oncogenic signaling as a cancer treatment strategy. Cancer discovery (2024)
Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M Fernandes Neto, Frank van Gemert, Soufiane M C Mourragui, Chrysa Papagianni, Hendrik J Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H S Wilms, Marcelo Santos da Silva, Robin A Jansen, Antonio Mulero-Sanchez, Elke Malzer, August Vidal Bel, Cristina Santos, Ramón Salazar, Rosangela A M Wailemann, Thompson E P Torres, Giulia De Conti, Jonne A Raaijmakers, Petur Snaebjornsson, Sheng-Xian Yuan, Wenxin Qin, John S Kovach, Hugo Aguirre Armelin, Hein Te Riele, Alexander van Oudernaarden, Haojie Jin, Roderick L Beijersbergen, Alberto Villanueva, René H Medema, René Bernards
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy. Cancer discovery 14 (7) (2024)
Marie-Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin, Isabelle Soubeyran, Sonia San José, Serena Peirone, Livia Caizzi, Sandra Vietti Michelina, Aurelien Bourdon, Xinan Wang, Daniel Alvarez-Villanueva, Maria Martinez-Iniesta, August Vidal Bel, Telmo Rodrigues, María Carmen García-Macías, Mark M Awad, Ernest Nadal, Alberto Villanueva, Antoine Italiano, Matteo Cereda, David Santamaría, Chiara Ambrogio
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade. Nature communications 15 (1) (2024)
Maria Eugénia Marques da Costa, Sakina Zaidi, Jean Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J Morscher, Anouchka Laurent, Sebastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaëlle Pierron, Olivier O Delattre, Gudrun Schleiermacher, Didier Surdez, Didier Frappaz
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors. Communications biology 6 (1) (2023)
Juana Fernández-Rodríguez, Edgar Creus-Bachiller, Xiaohu Zhang, Maria Martinez-Iniesta, Sara Ortega-Bertran, Rajarashi Guha, Craig J Thomas, Margaret R Wallace, Cleofe Romagosa, Lourdes Salazar-Huayna, Karlyne M Reilly, Jaishri O Blakely, Jordi Serra-Musach, Miguel Angel Pujana, Eduard Serra, Alberto Villanueva, Marc Ferrer, Conxi Lazaro Garcia
A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors. Molecular cancer therapeutics 21 (7) (2022)
Laura Solé, Teresa Lobo-Jarne, Daniel Alvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén, Marta Guix, Irene Sangrador, Catalina Rozalén, Anna Vert, Antonio Barbachano, Joan Lop, Marta Salido, Beatriz Bellosillo, Raquel García-Romero, Marta Garrido, Jessica González, María Martínez-Iniesta, Erika López-Arribillaga, Ramón Salazar, Clara Montagut, Ferràn Torres, Mar Iglesias, Toni Celià-Terrassa, Alberto Muñoz, Alberto Villanueva, Anna Bigas, Lluís Espinosa
p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis. Nature communications 13 (1) (2022)
Bram Herpers, Berina Eppink, Mark I James, Carme Cortina, Adrià Cañellas-Socias, Sylvia F Boj, Xavier Hernando-Momblona, Dominik Glodzik, Rob C Roovers, Marc van de Wetering, Carina Bartelink-Clements, Vanessa Zondag-van der Zande, Jara García Mateos, Kuan Yan, Lucia Salinaro, Abdul Basmeleh, Szabolcs Fatrai, David Maussang, Jeroen J Lammerts van Bueren, Irene Chicote, Garazi Serna, Laia Cabellos, Lorena Ramírez, Paolo G Nuciforo, Ramon Salazar, Cristina Santos, Alberto Villanueva, Camille Stephan-Otto Attolini, Elena Sancho, Hector G Palmer, Josep Tabernero, Michael R Stratton, John de Kruif, Ton Logtenberg, Hans Clevers, Leo S Price, Robert G J Vries, Eduard Batlle, Mark Throsby
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors. Nature cancer 3 (4) (2022)
Carmen Martínez-Fernández, Milana A Bergamino, Alfonso Schiavi, David Brena, Natascia Ventura, Sebastian Honnen, Alberto Villanueva, Ernest Nadal, Julián Cerón
Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans. Disease models & mechanisms 15 (3) (2022)
Clara Alcon, Fernando Martín Silva, Estela Prada, Jaume Mora, Aroa Soriano Fernandez, Gabriela Guillén Burrieza, Soledad Gallego Melcon, Josep Roma, Josep Samitier, Alberto Villanueva, Joan Montero
MEK and MCL-1 sequential inhibition synergize to enhance rhabdomyosarcoma treatment. Cell death discovery 8 (1) (2022)
Chaobo Chen, Hanghang Wu, Hui Ye, Agustín Tortajada, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, August Vidal Bel, Maria Isabel Peligros, Johanna Reissing, Karen Schmidt, Mohamed Ramadan Mohamed, Kang Zheng, Amaia Lujambio, Maria J Iraburu, Leticia Colyn, Maria Ujue Latasa, María Arechederra, Maite G Férnandez-Barrena, Carmen Berasain, Javier Vaquero, Rafael Bañares, Leonard J Nelson, Christian Trautwein, Roger J Davis, Eduardo Martinez-Naves, Yulia A Nevzorova, Alberto Villanueva, Matias A Avila, Francisco Javier Cubero
Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease. Cancers 14 (1) (2021)
Josune Alonso-Marañón, Alberto Villanueva, Josep Maria Piulats, María Martínez-Iniesta, Laura Solé, Juan Martín-Liberal, Sonia Segura, Ramon M Pujol, Mar Iglesias, Anna Bigas, Fernando Gallardo, Lluís Espinosa
Combination of chemotherapy with BRAF inhibitors results in effective eradication of malignant melanoma by preventing ATM-dependent DNA repair. Oncogene 40 (31) (2021)
Octavio A Romero, Andrea Vilarrubi, Juan J Alburquerque-Bejar, Antonio Gómez, Alvaro Andrades, Deborah Trastulli, Eva Pros, Fernando Setien, Sara Verdura, Lourdes Farre, Juan F Martín-Tejera, Paula Llabata, Ana Oaknin, Maria Saigí, Josep M Piulats, Xavier Matias-Guiu, Pedro P Medina, August Vidal Bel, Alberto Villanueva, Montse Sanchez-Cespedes
SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade. Nature communications 12 (1) (2021)
Clara Alcon, Albert Manzano-Muñoz, Estela Prada, Jaume Mora, Aroa Soriano Fernandez, Gabriela Guillén Burrieza, Soledad Gallego Melcon, Josep Roma, Josep Samitier, Alberto Villanueva, Joan Montero
Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance. Cell death & disease 11 (8) (2020)
Margalida Rosselló-Tortella, Pere Llinàs-Arias, Yuriko Sakaguchi, Kenjyo Miyauchi, Veronica Davalos, Fernando Setien, Maria Eréndira Calleja-Cervantes, David Piñeyro, Jesús Martínez-Gómez, Sonia Guil, Ricky Joshi, Alberto Villanueva, Tsutomu Suzuki, Manel Esteller
Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer. Proceedings of the National Academy of Sciences of the United States of America 117 (34) (2020)
João M Fernandes Neto, Ernest Nadal, Evert Bosdriesz, Salo N Ooft, Lourdes Farre, Chelsea M McLean, Sjoerd Klarenbeek, Anouk Jurgens, Hannes Hagen, Liqin Wang, Enriqueta Felip, Alex Martinez-Marti, August Vidal, Emile E Voest, Lodewyk F A Wessels, Olaf van Tellingen, Alberto Villanueva, René Bernards
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours. Nature communications 11 (1) (2020)
Laia Piqué, Alexia Martinez de Paz, David Piñeyro, Anna Martinez-Cardus, Manuel Castro de Moura, Pere Llinàs-Arias, Fernando Setien, Jorge Gómez-Miragaya, Eva Gonzalez-Suarez, Stefan Sigurdsson, Jon G Jonasson, Alberto Villanueva, August Vidal, Veronica Davalos, Manel Esteller
Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer. Oncogene 38 (45) (2019)