Alex Avdeef

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 14

Top Topics

Machine Learning

Drug Administration

Molecular Dynamics Simulations

Top Venues

Molecular pharmaceutics

Journal of chemical information and modeling

This page only lists publications with an associated author ORCID identifier.

Publications

Szabina Kádár, Dóra Csicsák, Petra Tőzsér, Attila Farkas, Tamás Pálla, Arash Mirzahosseini, Blanka Tóth, Gergő Tóth, Béla Fiser, Péter Horváth, János Madarász, Alex Avdeef, Krisztina Takács-Novák, Bálint Sinkó, Enikő Borbás, Gergely Völgyi
Understanding the pH Dependence of Supersaturation State-A Case Study of Telmisartan. Pharmaceutics 14 (8) (2022)
Alex Avdeef
Thickness of the aqueous boundary layer in stirred microtitre plate permeability assays (PAMPA and Caco-2), based on the Levich equation. ADMET & DMPK 10 (4) (2022)
Alex Avdeef, Manfred Kansy
Predicting Solubility of Newly-Approved Drugs (2016-2020) with a Simple ABSOLV and GSE( Flexible-Acceptor ) Consensus Model Outperforming Random Forest Regression. Journal of solution chemistry 51 (9) (2022)
Olivera S Marković, Nirali G Patel, Abu T M Serajuddin, Alex Avdeef, Tatjana Ž Verbić
Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pH max Domains with a Gibbs Phase Rule "Soft" Constraints. Molecular pharmaceutics 19 (2) (2022)
Alex Avdeef
Thickness of the aqueous boundary layer in stirred microtitre plate permeability assays (PAMPA and Caco-2), based on the Levich equation. ADMET & DMPK 10 (4) (2022)
Alex Avdeef
Disproportionation of Pharmaceutical Salts: pHmax and Phase-Solubility/pH Variance. Molecular pharmaceutics 18 (7) (2021)
Alex Avdeef, Manfred Kansy
Can small drugs predict the intrinsic aqueous solubility of 'beyond Rule of 5' big drugs? ADMET & DMPK 8 (3) (2020)
Li Di, Per Artursson, Alex Avdeef, Leslie Z Benet, J Brian Houston, Manfred Kansy, Edward H Kerns, Hans Lennernäs, Dennis A Smith, Kiyohiko Sugano
The Critical Role of Passive Permeability in Designing Successful Drugs. ChemMedChem 15 (20) (2020)
Antonio Llinas, Ioana Oprisiu, Alex Avdeef
Findings of the Second Challenge to Predict Aqueous Solubility. Journal of chemical information and modeling 60 (10) (2020)
Alex Avdeef, Manfred Kansy
"Flexible-Acceptor" General Solubility Equation for beyond Rule of 5 Drugs. Molecular pharmaceutics 17 (10) (2020)
Christel A S Bergstrom, Alex Avdeef
Perspectives in solubility measurement and interpretation. ADMET & DMPK 7 (2) (2019)
Alex Avdeef
Multi-lab intrinsic solubility measurement reproducibility in CheqSol and shake-flask methods. ADMET & DMPK 7 (3) (2019)
Antonio Llinas, Alex Avdeef
Solubility Challenge Revisited after Ten Years, with Multilab Shake-Flask Data, Using Tight (SD ∼ 0.17 log) and Loose (SD ∼ 0.62 log) Test Sets. Journal of chemical information and modeling 59 (6) (2019)
Alex Avdeef
Cocrystal Solubility Product Prediction Using an in combo Model and Simulations to Improve Design of Experiments. Pharmaceutical research 35 (2) (2018)