Li Di

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Venues

The AAPS journal

Biopharmaceutics & drug disposition

Journal of medicinal chemistry

Pharmaceutical research

This page only lists publications with an associated author ORCID identifier.

Publications

Jie Chen, Lloyd Wei Tat Tang, Samantha Jordan, Makayla Harrison, Gabrielle M Gualtieri, Ethan DaSilva, Danial Morris, Gary Bora, Ye Che, Li Di
Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates. The AAPS journal 26 (2) (2024)
Sam Zhang, Christine C Orozco, Lloyd Wei Tat Tang, Jillian Racich, Anthony A Carlo, George Chang, David Tess, Christopher Keefer, Li Di
Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery. The AAPS journal 26 (3) (2024)
Jianhua Liu, Daria Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy Yang, Ye Che, George Chang, Matthew D Troutman, Li Di
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes. The AAPS journal 26 (3) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry (2024)
Jianhua Liu, Daria Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy Yang, Ye Che, George Chang, Matthew D Troutman, Li Di
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes. The AAPS journal 26 (3) (2024)
Sam Zhang, Christine C Orozco, Lloyd Wei Tat Tang, Jillian Racich, Anthony A Carlo, George Chang, David Tess, Christopher Keefer, Li Di
Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery. The AAPS journal 26 (3) (2024)
Jianhua Liu, Daria Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy Yang, Ye Che, George Chang, Matthew D Troutman, Li Di
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes. The AAPS journal 26 (3) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
Jianhua Liu, Daria Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy Yang, Ye Che, George Chang, Matthew D Troutman, Li Di
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes. The AAPS journal 26 (3) (2024)
Jie Chen, Lloyd Wei Tat Tang, Samantha Jordan, Makayla Harrison, Gabrielle M Gualtieri, Ethan DaSilva, Danial Morris, Gary Bora, Ye Che, Li Di
Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates. The AAPS journal 26 (2) (2024)
Sam Zhang, Christine C Orozco, Lloyd Wei Tat Tang, Jillian Racich, Anthony A Carlo, George Chang, David Tess, Christopher Keefer, Li Di
Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery. The AAPS journal 26 (3) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
Sam Zhang, Christine C Orozco, Lloyd Wei Tat Tang, Jillian Racich, Anthony A Carlo, George Chang, David Tess, Christopher Keefer, Li Di
Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery. The AAPS journal 26 (3) (2024)
Jie Chen, Lloyd Wei Tat Tang, Samantha Jordan, Makayla Harrison, Gabrielle M Gualtieri, Ethan DaSilva, Danial Morris, Gary Bora, Ye Che, Li Di
Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates. The AAPS journal 26 (2) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry (2024)
Jie Chen, Lloyd Wei Tat Tang, Samantha Jordan, Makayla Harrison, Gabrielle M Gualtieri, Ethan DaSilva, Danial Morris, Gary Bora, Ye Che, Li Di
Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates. The AAPS journal 26 (2) (2024)
Kazuko Sagawa, Jian Lin, Rohit Jaini, Li Di
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics. Pharmaceutical research (2023)
Siennah R Greenfield, Heather Eng, Qingyi Yang, Chunyang Guo, Laura J Byrnes, Alyssa L Dantonio, Graham M West, Li Di, Amit S Kalgutkar
Species differences in plasma protein binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease inhibitor nirmatrelvir. Xenobiotica; the fate of foreign compounds in biological systems (2023)
Li Di
Quantitative Translation of Substrate Intrinsic Clearance from Recombinant CYP1A1 to Humans. The AAPS journal 25 (6) (2023)
David Tess, George C Chang, Christopher Keefer, Anthony Carlo, Rhys Jones, Li Di
In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes. The AAPS journal 25 (3) (2023)
Christopher E Keefer, George Chang, Li Di, Nathaniel A Woody, David A Tess, Sarah M Osgood, Brendon Kapinos, Jill Racich, Anthony A Carlo, Amanda Balesano, Nicholas Ferguson, Christine C Orozco, Larisa Zueva, Lina Luo
The Comparison of Machine Learning and Mechanistic In Vitro-In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance. Molecular pharmaceutics (2023)
Li Di
Special Issue on Applications of in Vitro, in Vivo, and Modelling & Simulation Tools for CNS Drug Disposition. Biopharmaceutics & drug disposition (2022)
Li Di
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2022)
Li Di
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2022)
Li Di
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2022)
David A Tess, Sangwoo Ryu, Li Di
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species. Pharmaceutical research 39 (7) (2022)
Heather Eng, Alyssa L Dantonio, Eugene P Kadar, R Scott Obach, Li Di, Jian Lin, Nandini C Patel, Britton Boras, Gregory S Walker, Jonathan J Novak, Emi Kimito, Ravi Shankar Prasad Singh, Amit S Kalgutkar
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans. Drug metabolism and disposition: the biological fate of chemicals 50 (5) (2022)
Li Di
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2022)
Sangwoo Ryu, David Tess, Li Di
Addressing the Accuracy of Plasma Protein Binding Measurement for Highly Bound Compounds Using the Dilution Method. The AAPS journal 25 (1) (2022)
Li Di
Special issue on applications of in vitro, in vivo, and modeling and simulation tools for central nervous system drug disposition. Biopharmaceutics & drug disposition (2022)
Li Di, Amanda Balesano, Samantha Jordan, Sophia M Shi
The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation. The AAPS journal 23 (1) (2021)
Jonathan J Novak, Woodrow Burchett, Li Di
Effects of low temperature on blood-to-plasma ratio measurement. Biopharmaceutics & drug disposition 42 (5) (2021)
Li Di, Per Artursson, Alex Avdeef, Leslie Z Benet, J Brian Houston, Manfred Kansy, Edward H Kerns, Hans Lennernäs, Dennis A Smith, Kiyohiko Sugano
The Critical Role of Passive Permeability in Designing Successful Drugs. ChemMedChem 15 (20) (2020)
Xin Yang, Sangwoo Ryu, Li Di
Dasotraline as a selective cytochrome 2B6 inhibitor for reaction phenotyping. Biopharmaceutics & drug disposition 40 (9) (2020)
Chuang Lu, Li Di
In vitro and in vivo methods to assess pharmacokinetic drug- drug interactions in drug discovery and development. Biopharmaceutics & drug disposition 41 (1-2) (2020)
Tristan S Maurer, Dennis Smith, Kevin Beaumont, Li Di
Dose Predictions for Drug Design. Journal of medicinal chemistry 63 (12) (2020)
Sangwoo Ryu, Jonathan J Novak, Roshan Patel, Phillip Yates, Li Di
The impact of low temperature on fraction unbound for plasma and tissue. Biopharmaceutics & drug disposition 39 (9) (2018)
Dennis A Smith, Kevin Beaumont, Tristan S Maurer, Li Di
Clearance in Drug Design. Journal of medicinal chemistry 62 (5) (2018)
Dennis A Smith, Kevin Beaumont, Tristan S Maurer, Li Di
Relevance of Half-Life in Drug Design. Journal of medicinal chemistry 61 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Li Di