Alex C Keene (Keene Ac, Alex Keene, A C Keene)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Topics

Dna Methylation

Depressive Symptoms

Genome Wide Association Study

Top Venues

Science advances

bioRxiv : the preprint server for biology

Journal of experimental zoology. Part B, Molecular and developmental evolution

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Robert A Kozol, Canavan A, Tolentino B, Alex C Keene, Johanna E Kowalko, Erik R Duboue
Evolution of a central dopamine circuit underlies adaptation of light-evoked sensorimotor response in the blind cavefish, Astyanax mexicanus . bioRxiv : the preprint server for biology (2024)
Olajumoke Ogunlusi, Mrinmoy Sarkar, Arhit Chakrabarti, Devon J Boland, Tristan Nguyen, James Sampson, Christian Nguyen, Danielle Fails, Yava L Jones-Hall, Loning Fu, Bani Mallick, Alex C Keene, Jeff R Jones, Tapasree Roy Sarkar
Disruption of Circadian Clock Induces Abnormal Mammary Morphology and Aggressive Basal Tumorigenesis by Enhancing LILRB4 Signaling. bioRxiv : the preprint server for biology (2024)
Robert A Kozol, A Canavan, B Tolentino, Alex C Keene, Johanna E Kowalko, Erik R Duboue
Evolution of a central dopamine circuit underlies adaptation of light-evoked sensorimotor response in the blind cavefish, Astyanax mexicanus . bioRxiv : the preprint server for biology (2024)
Olajumoke Ogunlusi, Mrinmoy Sarkar, Arhit Chakrabarti, Devon J Boland, Tristan Nguyen, James Sampson, Christian Nguyen, Danielle Fails, Yava L Jones-Hall, Loning Fu, Bani Mallick, Alex C Keene, Jeff R Jones, Tapasree Roy Sarkar
Circadian rhythm disruption alters mammary gland morphology and accelerates "cold" aggressive tumorigenesis through a LILRB4-dependent pathway. bioRxiv : the preprint server for biology (2024)
Elizabeth B Brown, Evan Lloyd, Alfonso Martin-Peña, Samuel McFarlane, Anupama Dahanukar, Alex C Keene
Aging is associated with a modality-specific decline in taste. bioRxiv : the preprint server for biology (2024)
Rachel L Moran, Emilie J Richards, Claudia Patricia Ornelas-García, Joshua B Gross, Alexandra Donny, Jonathan Wiese, Alex C Keene, Johanna E Kowalko, Nicolas Rohner, Suzanne E McGaugh
Selection-driven trait loss in independently evolved cavefish populations. Nature communications 14 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Evan Lloyd, Aakriti Rastogi, Niah Holtz, Ben Aaronson, R Craig Albertson, Alex C Keene
Ontogeny and social context regulate the circadian activity patterns of Lake Malawi cichlids. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (2023)
Rachel L Moran, Emilie J Richards, Claudia Patricia Ornelas-García, Joshua B Gross, Alexandra Donny, Jonathan Wiese, Alex C Keene, Johanna E Kowalko, Nicolas Rohner, Suzanne E McGaugh
Selection-driven trait loss in independently evolved cavefish populations. Nature communications 14 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Rachel L Moran, Emilie J Richards, Claudia Patricia Ornelas-García, Joshua B Gross, Alexandra Donny, Jonathan Wiese, Alex C Keene, Johanna E Kowalko, Nicolas Rohner, Suzanne E McGaugh
Selection-driven trait loss in independently evolved cavefish populations. Nature communications 14 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Justin Palermo, Alessandra Chesi, Amber J Zimmerman, Shilpa Sonti, Matthew C Pahl, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Diego R Mazzotti, Allan I Pack, Phillip R Gehrman, Struan F A Grant, Alex C Keene
Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Science advances 9 (1) (2023)
Elizabeth B Brown, Jiwei Zhang, Evan Lloyd, Elizabeth Lanzon, Valentina Botero, Seth M Tomchik, Alex C Keene
Neurofibromin 1 mediates sleep depth in Drosophila. PLoS genetics 19 (12) (2023)
Rachel L Moran, Emilie J Richards, Claudia Patricia Ornelas-García, Joshua B Gross, Alexandra Donny, Jonathan Wiese, Alex C Keene, Johanna E Kowalko, Nicolas Rohner, Suzanne E McGaugh
Selection-driven trait loss in independently evolved cavefish populations. Nature communications 14 (1) (2023)
Kazuma Murakami, Justin Palermo, Bethany A Stanhope, Allen G Gibbs, Alex C Keene
A screen for sleep and starvation resistance identifies a wake-promoting role for the auxiliary channel unc79. G3 (Bethesda, Md.) 11 (8) (2022)
Camila Oliva, Nicole K Hinz, Wayne Robinson, Alexys M Barrett Thompson, Julianna Booth, Lina M Crisostomo, Samantha Zanineli, Maureen Tanner, Evan Lloyd, Morgan O'Gorman, Brittnee McDole, Alexandra Paz, Rob Kozol, Elizabeth B Brown, Johanna E Kowalko, Yaouen Fily, Erik R Duboue, Alex C Keene
Characterizing the genetic basis of trait evolution in the Mexican cavefish. Evolution & development 24 (5) (2022)
Annabel Perry, Suzanne E McGaugh, Alex C Keene, Heath Blackmon
CaveCrawler: an interactive analysis suite for cavefish bioinformatics. G3 (Bethesda, Md.) 12 (8) (2022)
Katya L Mack, James B Jaggard, Jenna L Persons, Emma Y Roback, Courtney N Passow, Bethany A Stanhope, Estephany Ferrufino, Dai Tsuchiya, Sarah E Smith, Brian D Slaughter, Johanna E Kowalko, Nicolas Rohner, Alex C Keene, Suzanne E McGaugh
Repeated evolution of circadian clock dysregulation in cavefish populations. PLoS genetics 17 (7) (2021)
Evan Lloyd, Brian Chhouk, Andrew J Conith, Alex C Keene, R Craig Albertson
Diversity in rest-activity patterns among Lake Malawi cichlid fishes suggests a novel axis of habitat partitioning. The Journal of experimental biology 224 (7) (2021)
Elizabeth B Brown, Kreesha D Shah, Justin Palermo, Manali Dey, Anupama Dahanukar, Alex C Keene
Ir56d-dependent fatty acid responses in Drosophila uncover taste discrimination between different classes of fatty acids. eLife 10 (2021)
Itzel Sifuentes-Romero, Estephany Ferrufino, Sunishka Thakur, Lauren A Laboissonniere, Michael Solomon, Courtney L Smith, Alex C Keene, Jeffrey M Trimarchi, Johanna E Kowalko
Repeated evolution of eye loss in Mexican cavefish: Evidence of similar developmental mechanisms in independently evolved populations. Journal of experimental zoology. Part B, Molecular and developmental evolution 334 (7-8) (2020)
Estelle L S Pamboro, Elizabeth B Brown, Alex C Keene
Dietary fatty acids promote sleep through a taste-independent mechanism. Genes, brain, and behavior 19 (4) (2020)
Suzanne E McGaugh, Johanna E Kowalko, Erik R Duboue, Peter Lewis, Tamara Anne Franz-Odendaal, Nicolas Rohner, Joshua B Gross, Alex C Keene
Dark world rises: The emergence of cavefish as a model for the study of evolution, development, behavior, and disease. Journal of experimental zoology. Part B, Molecular and developmental evolution 334 (7-8) (2020)
Suzanne E McGaugh, Courtney N Passow, James Brian Jaggard, Bethany A Stahl, Alex C Keene
Unique transcriptional signatures of sleep loss across independently evolved cavefish populations. Journal of experimental zoology. Part B, Molecular and developmental evolution 334 (7-8) (2020)
Alexandra Paz, Brittnee McDole, Johanna E Kowalko, Erik R Duboue, Alex C Keene
Evolution of the acoustic startle response of Mexican cavefish. Journal of experimental zoology. Part B, Molecular and developmental evolution 334 (7-8) (2020)
Jacqueline S R Chin, Cody L Loomis, Lydia T Albert, Shirley Medina-Trenche, Johanna Kowalko, Alex C Keene, Erik R Duboue
Analysis of stress responses in Astyanax larvae reveals heterogeneity among different populations. Journal of experimental zoology. Part B, Molecular and developmental evolution 334 (7-8) (2020)
Elizabeth B Brown, Kreesha D Shah, Richard Faville, Benjamin Kottler, Alex C Keene
Drosophila insulin-like peptide 2 mediates dietary regulation of sleep intensity. PLoS genetics 16 (3) (2020)
James B Jaggard, Evan Lloyd, Anders Yuiska, Adam Patch, Yaouen Fily, Johanna E Kowalko, Lior Appelbaum, Erik R Duboue, Alex C Keene
Cavefish brain atlases reveal functional and anatomical convergence across independently evolved populations. Science advances 6 (38) (2020)
Elizabeth B Brown, Melissa E Slocumb, Milan Szuperak, Arianna Kerbs, Allen G Gibbs, Matthew S Kayser, Alex C Keene
Starvation resistance is associated with developmentally specified changes in sleep, feeding and metabolic rate. The Journal of experimental biology 222 (Pt 3) (2019)
Maria E Yurgel, Priyanka Kakad, Meet Zandawala, Dick R Nässel, Tanja A Godenschwege, Alex C Keene
A single pair of leucokinin neurons are modulated by feeding state and regulate sleep-metabolism interactions. PLoS biology 17 (2) (2019)
Maria E Yurgel, Kreesha D Shah, Elizabeth B Brown, Carter Burns, Ryan A Bennick, Justin R DiAngelo, Alex C Keene
Ade2 Functions in the Drosophila Fat Body To Promote Sleep. G3 (Bethesda, Md.) 8 (11) (2018)
Elizabeth B Brown, Joshua Torres, Ryan A Bennick, Valerie Rozzo, Arianna Kerbs, Justin R DiAngelo, Alex C Keene
Variation in sleep and metabolic function is associated with latitude and average temperature in Drosophila melanogaster. Ecology and evolution 8 (8) (2018)
Alex C Keene, Erik R Duboue
The origins and evolution of sleep. The Journal of experimental biology 221 (Pt 11) (2018)
James B Jaggard, Bethany A Stahl, Evan Lloyd, David A Prober, Erik R Duboue, Alex C Keene
Hypocretin underlies the evolution of sleep loss in the Mexican cavefish. eLife 7 (2018)
Bethany A Stahl, Alex C Keene
To rebound or not to rebound. eLife 6 (2017)
James Jaggard, Beatriz G Robinson, Bethany A Stahl, Ian Oh, Pavel Masek, Masato Yoshizawa, Alex C Keene
The lateral line confers evolutionarily derived sleep loss in the Mexican cavefish. The Journal of experimental biology 220 (Pt 2) (2017)
John M Tauber, Elizabeth B Brown, Yuanyuan Li, Maria E Yurgel, Pavel Masek, Alex C Keene
A subset of sweet-sensing neurons identified by IR56d are necessary and sufficient for fatty acid taste. PLoS genetics 13 (11) (2017)