Alexander Edward Heazell (A E P Heazell, Christopher J Weir, A Heazell, Alexander E P Heazell, Alexander Heazell, Aep Heazell, Alexander Ep Heazell)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 71

Top Topics

Systematic Review

Top Venues

BJOG : an international journal of obstetrics and gynaecology

Acta obstetricia et gynecologica Scandinavica

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Sukainah Y Al Khalaf, Alexander Edward Heazell, Marius Kublickas, Karolina Kublickiene, Ali S Khashan
Risk of stillbirth after a previous caesarean delivery: A Swedish nationwide cohort study. BJOG : an international journal of obstetrics and gynaecology 131 (8) (2024)
Nienke A Spil, Kim E van Nieuwenhuizen, Rachel Rowe, James G Thornton, Elizabeth Murphy, Evelyn Verheijen, Clifford L Shelton, Alexander Edward Heazell
The carbon footprint of different modes of birth in the UK and the Netherlands: An exploratory study using life cycle assessment. BJOG : an international journal of obstetrics and gynaecology 131 (5) (2024)
Chloe A Brady, Laura B Ford, Chloe Moss, Zhiyong Zou, Ian P Crocker, Alexander Edward Heazell
Virtual crossmatching reveals upregulation of placental HLA-Class II in chronic histiocytic intervillositis. Scientific reports 14 (1) (2024)
Alexander Edward Heazell, Jack Wilkinson, R Katie Morris, Nigel A B Simpson, Lucy K Smith, Tomasina Stacey, Claire Storey, Lucy E Higgins
Mothers working to prevent early stillbirth study (MiNESS 20-28): a case-control study protocol. BMJ open 14 (1) (2024)
Chloe A Brady, Laura B Ford, Chloe Moss, Zhiyong Zou, Ian P Crocker, Alexander Edward Heazell
Virtual crossmatching reveals upregulation of placental HLA-Class II in chronic histiocytic intervillositis. Scientific reports 14 (1) (2024)
Elizabeth Camacho Fonseca, Katherine J Gold, Margaret Murphy, Claire Storey, Alexander Edward Heazell
Measuring EQ-5D-5L utility values in parents who have experienced perinatal death. The European journal of health economics : HEPAC : health economics in prevention and care (2024)
Alexander Edward Heazell, Jack Wilkinson, R Katie Morris, Nigel A B Simpson, Lucy K Smith, Tomasina Stacey, Claire Storey, Lucy E Higgins
Mothers working to prevent early stillbirth study (MiNESS 20-28): a case-control study protocol. BMJ open 14 (1) (2024)
Sukainah Y Al Khalaf, Alexander Edward Heazell, Marius Kublickas, Karolina Kublickiene, Ali S Khashan
Risk of stillbirth after a previous caesarean delivery: A Swedish nationwide cohort study. BJOG : an international journal of obstetrics and gynaecology (2024)
Chloe A Brady, Laura B Ford, Chloe Moss, Zhiyong Zou, Ian P Crocker, Alexander Edward Heazell
Virtual crossmatching reveals upregulation of placental HLA-Class II in chronic histiocytic intervillositis. Scientific reports 14 (1) (2024)
Alexander Edward Heazell, Jack Wilkinson, R Katie Morris, Nigel A B Simpson, Lucy K Smith, Tomasina Stacey, Claire Storey, Lucy E Higgins
Mothers working to prevent early stillbirth study (MiNESS 20-28): a case-control study protocol. BMJ open 14 (1) (2024)
Nienke A Spil, Kim E van Nieuwenhuizen, Rachel Rowe, James G Thornton, Elizabeth Murphy, Evelyn Verheijen, Clifford L Shelton, Alexander Edward Heazell
The carbon footprint of different modes of birth in the UK and the Netherlands: An exploratory study using life cycle assessment. BJOG : an international journal of obstetrics and gynaecology (2024)
Nienke A Spil, Kim E van Nieuwenhuizen, Rachel Rowe, James G Thornton, Elizabeth Murphy, Evelyn Verheijen, Clifford L Shelton, Alexander Edward Heazell
The carbon footprint of different modes of birth in the UK and the Netherlands: An exploratory study using life cycle assessment. BJOG : an international journal of obstetrics and gynaecology 131 (5) (2024)
Alexander Edward Heazell, Jack Wilkinson, R Katie Morris, Nigel A B Simpson, Lucy K Smith, Tomasina Stacey, Claire Storey, Lucy E Higgins
Mothers working to prevent early stillbirth study (MiNESS 20-28): a case-control study protocol. BMJ open 14 (1) (2024)
Chloe A Brady, Laura B Ford, Chloe Moss, Zhiyong Zou, Ian P Crocker, Alexander Edward Heazell
Virtual crossmatching reveals upregulation of placental HLA-Class II in chronic histiocytic intervillositis. Scientific reports 14 (1) (2024)
Alexander Edward Heazell, Jack Wilkinson, R Katie Morris, Nigel A B Simpson, Lucy K Smith, Tomasina Stacey, Claire Storey, Lucy E Higgins
Mothers working to prevent early stillbirth study (MiNESS 20-28): a case-control study protocol. BMJ open 14 (1) (2024)
Mary Ann Adams, Charlotte Bevan, Maria Booker, Julie Hartley, Alexander Edward Heazell, Elsa Montgomery, Natalie Jean Sanford, Maureen Treadwell, Jane Sandall
Strengthening open disclosure in maternity services in the English NHS: the DISCERN realist evaluation study. Health and social care delivery research 12 (22) (2024)
Billie F Bradford, Dexter J L Hayes, Stefanie Elisabeth Damhuis, Alexis Shub, Anna Akselsson, Ingela Radestad, Alexander Edward Heazell, Vicki J Flenady, Sanne J Gordijn
Decreased fetal movements: Report from the International Stillbirth Alliance conference workshop. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2023)
Isabelle Greatholder, Emma Tomlinson, Jack Wilkinson, Lucy E Higgins, Mark David Kilby, Alexander Edward Heazell
Evaluating antenatal risk in twin pregnancies-A feasibility study to identify modifiable factors associated with adverse pregnancy outcomes. Acta obstetricia et gynecologica Scandinavica (2023)
Alexander Edward Heazell, Fiona Holland, Jack Wilkinson
Information about fetal movements and stillbirth trends: analysis of time series data. BJOG : an international journal of obstetrics and gynaecology (2023)
Raille A Thompson, John M D Thompson, Jessica Wilson, Robin S Cronin, Edwin A Mitchell, Camille H Raynes-Greenow, Minglan Li, Tomasina Stacey, Alexander Edward Heazell, Louise M O'Brien, Lesley M E McCowan, Ngaire H Anderson
Risk Factors for Late Preterm and Term Stillbirth: A Secondary Analysis of an Individual Participant Data Meta-analysis. BJOG : an international journal of obstetrics and gynaecology (2023)
Keya Patel, Danielle Pirie, Alexander Edward Heazell, Bethan Morgan, Andrea Mary Woolner
Subsequent pregnancy outcomes after second trimester miscarriage or termination for medical/fetal reason: A systematic review and meta-analysis of observational studies. Acta obstetricia et gynecologica Scandinavica (2023)
R A Thompson, J M D Thompson, J Wilson, Robin S Cronin, E A Mitchell, C H Raynes-Greenow, M Li, T Stacey, Alexander Edward Heazell, L M O'Brien, L M E McCowan, N H Anderson
Risk factors for late preterm and term stillbirth: A secondary analysis of an individual participant data meta-analysis. BJOG : an international journal of obstetrics and gynaecology (2023)
John M D Thompson, Alexander Edward Heazell, Robin S Cronin, Jessica Wilson, Minglan Li, Adrienne Gordon, Lisa M Askie, Louise M O'Brien, Camille Raynes-Greenow, Tomasina Stacey, Edwin A Mitchell, Lesley M E McCowan, Billie F Bradford
Does fetal size affect maternal perception of fetal movements? Evidence from an individual participant data meta-analysis. Acta obstetricia et gynecologica Scandinavica (2023)
Alexander Edward Heazell, Fiona Holland, Jack Wilkinson
Information about fetal movements and stillbirth trends: Analysis of time series data. BJOG : an international journal of obstetrics and gynaecology (2023)
Sukainah Al Khalaf, Karolina Kublickiene, Marius Kublickas, Ali S Khashan, Alexander Edward Heazell
Risk of stillbirth and adverse pregnancy outcomes in a third pregnancy when an earlier pregnancy has ended in stillbirth. Acta obstetricia et gynecologica Scandinavica (2023)
Lucy Hammer, Alexander Edward Heazell, Andrew Povey, Jenny E Myers, John M D Thompson, Edward D Johnstone
Assessment of the association between ambient air pollution and stillbirth in the UK: Results from a secondary analysis of the MiNESS case-control study. BJOG : an international journal of obstetrics and gynaecology (2023)
Dexter J L Hayes, Declan Devane, Jo C Dumville, Sanne J Gordijn, Valerie Smith, Tanya Walsh, Alexander Edward Heazell
Development of core outcome sets for studies relating to awareness and clinical management of reduced fetal movement. BJOG : an international journal of obstetrics and gynaecology (2023)
Carol Bedwell, Valentina Actis Danna, Kutemba Lyangenda, Khuzuet Tuwele, Flora Kuzenza, Debora Kimaro, Happiness Shayo, Chisomo Petross, Isabella Chisuse, Alexander Edward Heazell, Suresh Victor, Bellington Vwalika, Tina Lavender
'Moving towards understanding', acceptability of investigations following stillbirth in sub-Saharan Africa: A grounded theory study. BJOG : an international journal of obstetrics and gynaecology 130 (1) (2022)
Mary Ann Adams, Rick Iedema, Alexander Edward Heazell, Maureen Treadwell, Maria Booker, Charlotte Bevan, Julie Hartley, Jane Sandall
Investigation of the critical factors required to improve the disclosure and discussion of harm with affected women and families: a study protocol for a qualitative, realist study in NHS maternity services (the DISCERN study). BMJ open 12 (2) (2022)
Debbie M Smith, Suzanne Thomas, Louise Stephens, Tracey A Mills, Christine Hughes, Joanna Beaumont, Alexander Edward Heazell
Women's experiences of a pregnancy whilst attending a specialist antenatal service for pregnancies after stillbirth or neonatal death: a qualitative interview study. Journal of psychosomatic obstetrics and gynaecology 43 (4) (2022)
Danya Bakhbakhi, Abigail Fraser, Dimitris Siasakos, Lisa Hinton, Anna Davies, Abi Merriel, James M N Duffy, Maggie Redshaw, Mary Lynch, Laura Timlin, Vicki Flenady, Alexander Edward Heazell, Soo Downe, Pauline Slade, Sara Brookes, Aleena M Wojcieszek, Margaret Murphy, Heloisa de Oliveira Salgado, Danielle Pollock, Neelam Aggarwal, Irene Attachie, Susannah Leisher, Wanijiru Kihusa, Kate Mulley, Lindsey Wimmer, null null, Christy Burden
Protocol for the development of a core outcome set for stillbirth care research (iCHOOSE Study). BMJ open 12 (2) (2022)
Kimberley Farrant, David Faluyi, Kylie Watson, Sarah Vause, Heather Birds, Shirley Rowbotham, Alexander Edward Heazell
Role of ethnicity in high-level obstetric clinical incidents: a review of cases from a large UK NHS maternity unit. BMJ open quality 11 (4) (2022)
Alexander Edward Heazell
Managing stillbirth: taking care to investigate the cause and provide care for bereaved families. Journal of perinatal medicine 50 (6) (2022)
Alexander Edward Heazell
Interventions to increase maternal awareness of fetal movements no more effective than standard care. BJOG : an international journal of obstetrics and gynaecology (2021)
Dell Horey, Frances M Boyle, Jillian Cassidy, Paul Richard Cassidy, Jan Jaap H M Erwich, Katherine J Gold, Mechthild M Gross, Alexander Edward Heazell, Susannah Hopkins Leisher, Margaret Murphy, Claudia Ravaldi, Dimitrios Siassakos, Claire Storey, Niccolò Lombardi, Aleena M Wojcieszek, Vicki J Flenady
Parents' experiences of care offered after stillbirth: An international online survey of high and middle-income countries. Birth (Berkeley, Calif.) 48 (3) (2021)
Christy Burden, Danya Bakhbakhi, Alexander Edward Heazell, Mary Lynch, Laura Timlin, Charlotte Bevan, Claire Storey, Jennifer J Kurinczuk, Dimitrios Siassakos
Parents' Active Role and ENgagement in The review of their Stillbirth/perinatal death 2 (PARENTS 2) study: a mixed-methods study of implementation. BMJ open 11 (3) (2021)
Nicole Graham, Louise Stephens, Edward D Johnstone, Alexander Edward Heazell
Can information regarding the index stillbirth determine risk of adverse outcome in a subsequent pregnancy? Findings from a single-center cohort study. Acta obstetricia et gynecologica Scandinavica 100 (7) (2021)
Yu Zhen Lau, Kate Widdows, Stephen A Roberts, Sheher Khizar, Gillian L Stephen, Saima Rauf, Alexander Edward Heazell
Assessment of the quality, content and perceived utility of local maternity guidelines in hospitals in England implementing the saving babies' lives care bundle to reduce stillbirth. BMJ open quality 9 (2) (2021)
Kate Widdows, Stephen A Roberts, Elizabeth Camacho Fonseca, Alexander Edward Heazell
Stillbirth rates, service outcomes and costs of implementing NHS England's Saving Babies' Lives care bundle in maternity units in England: A cohort study. PloS one 16 (4) (2021)
Lauren Rockliffe, Sarah Peters, Alexander Edward Heazell, Debbie M Smith
Understanding pregnancy as a teachable moment for behaviour change: a comparison of the COM-B and teachable moments models. Health psychology and behavioral medicine 10 (1) (2021)
Gordon C S Smith, Alexandros A Moraitis, David Wastlund, James G Thornton, Aris T Papageorghiou, Julia Sanders, Alexander Edward Heazell, Stephen Courtenay Robson, Ulla Sovio, Peter Brocklehurst, Edward C F Wilson
Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis. Health technology assessment (Winchester, England) 25 (15) (2021)
Marie-Eve Brien, Virginie Gaudreault, Katia Hughes, Dexter J L Hayes, Alexander Edward Heazell, Sylvie Girard
A Systematic Review of the Safety of Blocking the IL-1 System in Human Pregnancy. Journal of clinical medicine 11 (1) (2021)
Lauren Rockliffe, Sarah Peters, Alexander Edward Heazell, Debbie M Smith
Factors influencing health behaviour change during pregnancy: a systematic review and meta-synthesis. Health psychology review 15 (4) (2021)
Imogen Sharp, Temidayo Adeyeye, Linda Peacock, Amy Mahdi, Kimberley Farrant, Andrew N Sharp, Susan L Greenwood, Alexander Edward Heazell
Investigation of the outcome of pregnancies complicated by increased fetal movements and their relation to underlying causes - A prospective cohort study. Acta obstetricia et gynecologica Scandinavica 100 (1) (2020)
Megan C Sharps, Bernadette C Baker, Tatiana Guevara, Helen Bischof, Rebecca L Jones, Susan L Greenwood, Alexander Edward Heazell
Increased placental macrophages and a pro-inflammatory profile in placentas and maternal serum in infants with a decreased growth rate in the third trimester of pregnancy. American journal of reproductive immunology (New York, N.Y. : 1989) 84 (3) (2020)
Alexandros A Moraitis, Norman Shreeve, Ulla Sovio, Peter Brocklehurst, Alexander Edward Heazell, James G Thornton, Stephen Courtenay Robson, Aris Papageorghiou, Gordon C Smith
Universal third-trimester ultrasonic screening using fetal macrosomia in the prediction of adverse perinatal outcome: A systematic review and meta-analysis of diagnostic test accuracy. PLoS medicine 17 (10) (2020)
Christopher J Weir, Alexander Edward Heazell, Sonia Whyte, Jane E Norman
Evaluating improvement interventions using routine data to support a learning health system: research design, data access, analysis and reporting. BMJ quality & safety 29 (8) (2020)
Chloe A Brady, Charlotte Williams, Megan C Sharps, Amena Shelleh, Gauri Batra, Alexander Edward Heazell, Ian P Crocker
Chronic histiocytic intervillositis: A breakdown in immune tolerance comparable to allograft rejection? American journal of reproductive immunology (New York, N.Y. : 1989) 85 (3) (2020)
R Townsend, A Manji, John Allotey, Alexander Edward Heazell, L Jorgensen, L A Magee, Ben-Willem J Mol, Kie Snell, R D Riley, J Sandall, Gordon C S Smith, M Patel, B Thilaganathan, Peter Von Dadelszen, S Thangaratinam, A Khalil
Can risk prediction models help us individualise stillbirth prevention? A systematic review and critical appraisal of published risk models. BJOG : an international journal of obstetrics and gynaecology 128 (2) (2020)
R Townsend, F G Sileo, John Allotey, J Dodds, Alexander Edward Heazell, L Jorgensen, V B Kim, L Magee, Ben-Willem J Mol, J Sandall, Gordon C S Smith, B Thilaganathan, Peter Von Dadelszen, S Thangaratinam, A Khalil
Prediction of stillbirth: an umbrella review of evaluation of prognostic variables. BJOG : an international journal of obstetrics and gynaecology 128 (2) (2020)
Dexter J L Hayes, Jane Warland, Mana M Parast, Robert W Bendon, Junichi Hasegawa, Julia Banks, Laura Clapham, Alexander Edward Heazell
Umbilical cord characteristics and their association with adverse pregnancy outcomes: A systematic review and meta-analysis. PloS one 15 (9) (2020)
Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C Lean, Yinhui Lu, Karl E Kadler, Alan Kerby, Mark R Dilworth, Kathryn E Hentges, Alexander Edward Heazell
A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure. PloS one 15 (6) (2020)
Lucy E Higgins, Alexander Edward Heazell, Louise E Simcox, Edward D Johnstone
Intra-placental arterial Doppler: A marker of fetoplacental vascularity in late-onset placental disease? Acta obstetricia et gynecologica Scandinavica 99 (7) (2020)
Alexander Edward Heazell, J Budd, David J Field, Minglan Li, Robin S Cronin, B Bradford, Lesley M E McCowan, Edwin A Mitchell, Tomasina Stacey, D Roberts, John M D Thompson
Associations between social and behavioural factors and the risk of late stillbirth - findings from the Midland and North of England Stillbirth case-control study. BJOG : an international journal of obstetrics and gynaecology 128 (4) (2020)
Danya Bakhbakhi, Christy Burden, Claire Storey, Alexander Edward Heazell, Mary Lynch, Laura Timlin, Katherine Gold, Dimitrios Siassakos
PARENTS 2 Study: a qualitative study of the views of healthcare professionals and stakeholders on parental engagement in the perinatal mortality review-from 'bottom of the pile' to joint learning. BMJ open 8 (11) (2019)
Alexander Edward Heazell, Peter R Stone
Comments: Influence of the prone position on a stretcher for pregnant women on maternal and fetal hemodynamic parameters and comfort in pregnancy. Clinics (Sao Paulo, Brazil) 74 (2019)
Aleena M Wojcieszek, Alexander Edward Heazell, Philippa Middleton, David Ellwood, Robert M Silver, Vicki J Flenady
Research priorities and potential methodologies to inform care in subsequent pregnancies following stillbirth: a web-based survey of healthcare professionals, researchers and advocates. BMJ open 9 (6) (2019)
Lynne K Warrander, Emma Ingram, Alexander Edward Heazell, Edward D Johnstone
Evaluating the accuracy and precision of sonographic fetal weight estimation models in extremely early-onset fetal growth restriction. Acta obstetricia et gynecologica Scandinavica 99 (3) (2019)
Charlotte H Hulme, Anna Nicolaou, Sharon A Murphy, Alexander Edward Heazell, Jenny E Myers, Melissa Westwood
The effect of high glucose on lipid metabolism in the human placenta. Scientific reports 9 (1) (2019)
Alexander Edward Heazell
Need to ensure that improvements in stillbirth rates are also achieved in high-risk groups. Paediatric and perinatal epidemiology 34 (1) (2019)
Lisa M Daly, Glenn J Gardener, Victoria Bowring, Wendy Burton, Yogesh Chadha, David A Ellwood, J Frederik Frøen, Adrienne Gordon, Alexander Edward Heazell, Kassam Mahomed, Susan McDonald, Jane E Norman, Jeremy J N Oats, Vicki J Flenady
Care of pregnant women with decreased fetal movements: Update of a clinical practice guideline for Australia and New Zealand. The Australian & New Zealand journal of obstetrics & gynaecology 58 (4) (2018)
Kate Widdows, Holly E Reid, Stephen A Roberts, Elizabeth M Camacho, Alexander Edward Heazell
Saving babies' lives project impact and results evaluation (SPiRE): a mixed methodology study. BMC pregnancy and childbirth 18 (1) (2018)
Alexander Edward Heazell, Jayne Budd, Minglan Li, Robin Cronin, Billie Bradford, Lesley M E McCowan, Edwin A Mitchell, Tomasina Stacey, Bill Martin, Devender Roberts, John M D Thompson
Alterations in maternally perceived fetal movement and their association with late stillbirth: findings from the Midland and North of England stillbirth case-control study. BMJ open 8 (7) (2018)
Alexandra Crawford, Patrick Anyadi, Louise Stephens, Suzanne L Thomas, Holly Reid, Lucy E Higgins, Lynne K Warrander, Edward D Johnstone, Alexander Edward Heazell
A mixed-methods evaluation of continuous electronic fetal monitoring for an extended period. Acta obstetricia et gynecologica Scandinavica 97 (12) (2018)
Minglan Li, John M D Thompson, Robin S Cronin, Adrienne Gordon, Camille Raynes-Greenow, Alexander Edward Heazell, Tomasina Stacey, Vicki Culling, Victoria Bowring, Edwin A Mitchell, Lesley M E McCowan, Lisa Askie
The Collaborative IPD of Sleep and Stillbirth (Cribss): is maternal going-to-sleep position a risk factor for late stillbirth and does maternal sleep position interact with fetal vulnerability? An individual participant data meta-analysis study protocol. BMJ open 8 (4) (2018)
Lindsay Armstrong-Buisseret, Eleanor Mitchell, Trish Hepburn, Lelia Duley, Jim G Thornton, Tracy E Roberts, Claire Storey, Rebecca Smyth, Alexander Edward Heazell
Reduced fetal movement intervention Trial-2 (ReMIT-2): protocol for a pilot randomised controlled trial of standard care informed by the result of a placental growth factor (PlGF) blood test versus standard care alone in women presenting with reduced fetal movement at or after 36+ 0 weeks gestation. Trials 19 (1) (2018)
Alexander Edward Heazell, Jane Warland, Tomasina Stacey, Christin Coomarasamy, Jayne Budd, Edwin A Mitchell, Louise M O'Brien
Stillbirth is associated with perceived alterations in fetal activity - findings from an international case control study. BMC pregnancy and childbirth 17 (1) (2017)
Alexandra Crawford, Dexter J L Hayes, Edward D Johnstone, Alexander Edward Heazell
Women's experiences of continuous fetal monitoring - a mixed-methods systematic review. Acta obstetricia et gynecologica Scandinavica 96 (12) (2017)
Esther Aiyelaagbe, Rebecca E Scott, Victoria Holmes, Emma Lane, Alexander Edward Heazell
Assessing the quality of bereavement care after perinatal death: development and piloting of a questionnaire to assess parents' experiences. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 37 (7) (2017)
Billie F Bradford, John M D Thompson, Alexander Edward Heazell, Lesley M E Mccowan, Chris J D McKinlay
Understanding the associations and significance of fetal movements in overweight or obese pregnant women: a systematic review. Acta obstetricia et gynecologica Scandinavica 97 (1) (2017)
Alexander E P Heazell, Alexander Edward Heazell, Sarah J E Stock, Catherine J Calderwood, Sarah Cunningham Burley, J Frederik Froen, Michael Geary, Alyson Hunter, Fionnuala M McAuliffe, Edile Murdoch, Aryelly Rodriguez, Mary Ross-Davie, Janet Scott, Sonia Whyte, Jane E Norman
Can promoting awareness of fetal movements and focusing interventions reduce fetal mortality? A stepped-wedge cluster randomised trial (AFFIRM). BMJ open 7 (8) (2017)