Alvaro Macias (Álvaro Macías)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 24

Top Topics

Atrial Fibrillation

Congenital Heart Disease

Pulmonary Hypertension

Top Venues

Circulation research

Cardiovascular research

Science advances

Nature cardiovascular research

This page only lists publications with an associated author ORCID identifier.

Publications

Ana I Moreno-Manuel, Alvaro Macias, Francisco Miguel Cruz, Lilian K Gutiérrez, Fernando Martínez, Andrés González-Guerra, Isabel Martínez Carrascoso, Francisco José Bermúdez-Jimenez, Patricia Sánchez-Pérez, María Linarejos Vera-Pedrosa, Juan Manuel Ruiz-Robles, Juan Antonio Bernal, Jose Jalife
The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3. Cardiovascular research 120 (5) (2024)
Ana I Moreno-Manuel, Alvaro Macias, Francisco Miguel Cruz, Lilian K Gutiérrez, Fernando Martínez, Andrés González-Guerra, Isabel Martínez Carrascoso, Francisco José Bermúdez-Jimenez, Patricia Sánchez-Pérez, María Linarejos Vera-Pedrosa, Juan Manuel Ruiz-Robles, Juan Antonio Bernal, Jose Jalife
The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3. Cardiovascular research 120 (5) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP 2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research 134 (8) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Ana I Moreno-Manuel, Alvaro Macias, Francisco Miguel Cruz, Lilian K Gutiérrez, Fernando Martínez, Andrés González-Guerra, Isabel Martínez Carrascoso, Francisco José Bermúdez-Jimenez, Patricia Sánchez-Pérez, María Linarejos Vera-Pedrosa, Juan Manuel Ruiz-Robles, Juan Antonio Bernal, Jose Jalife
The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3. Cardiovascular research 120 (5) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP 2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research 134 (8) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP 2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research 134 (8) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP 2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research 134 (8) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Antonio R Artalejo, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular Kir2.1 C122Y Mutant Upsets Kir2.1-PIP 2 Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome. Circulation research 134 (8) (2024)
Ana I Moreno-Manuel, Alvaro Macias, Francisco Miguel Cruz, Lilian K Gutiérrez, Fernando Martínez, Andrés González-Guerra, Isabel Martínez Carrascoso, Francisco José Bermúdez-Jimenez, Patricia Sánchez-Pérez, María Linarejos Vera-Pedrosa, Juan Manuel Ruiz-Robles, Juan Antonio Bernal, Jose Jalife
The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3. Cardiovascular research 120 (5) (2024)
Ayelén M Santamans, Beatriz Cicuéndez, Alfonso Mora, María Villalba-Orero, Sanela Rajlic, Maria Crespo-Ruiz, Paula Vo, Madison Jerome, Alvaro Macias, Juan Antonio López, Magdalena Leiva, Susana F Rocha, Marta León, Elena Rodríguez, Luis Leiva, Aránzazu Pintor Chocano, Ines Garcia-Lunar, Ana García-Álvarez, Pablo Hernansanz Agustín, Víctor I Peinado, Joan Albert Barberà, Francesco Lavarra, Jesus Vazquez, Jessica Brooke Spinelli, Andreas Daiber, Eduardo Oliver, Guadalupe Sabio
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Science advances 10 (3) (2024)
Francisco Miguel Cruz, Alvaro Macias, Ana I Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Patricia Sánchez Pérez, Juan Manuel Ruiz Robles, Francisco José Bermúdez-Jiménez, Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias Santiago, Aitana Braza-Boils, Mercedes Martín-Martínez, Marta Gutierrez-Rodríguez, Juan Antonio Bernal, Esther Zorio-Grima, Juan Jiménez Jaimez, Jose Jalife
Extracellular cysteine disulfide bond break at Cys122 disrupts PIP 2 -dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome. bioRxiv : the preprint server for biology (2023)
Alvaro Macias, Rosa M Nevado, Cristina González-Gómez, Pilar Gonzalo, María Jesús Andrés-Manzano, Beatriz Dorado, Ignacio Benedicto, Vicente Andrés
Coronary and carotid artery dysfunction and K V 7 overexpression in a mouse model of Hutchinson-Gilford progeria syndrome. GeroScience (2023)
Alvaro Macias, Andrés Gonzalez-Guerra, Ana I Moreno-Manuel, Francisco M Cruz, Lilian K Gutiérrez, Nieves García-Quintáns, Marta Roche-Molina, Francisco Bermúdez-Jiménez, Vicente Andrés, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Juan A Bernal, Jose Jalife
Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. Nature cardiovascular research 1 (10) (2022)
Eric N Jimenez-Vazquez, Michael Arad, Alvaro Macias, Maria L Vera-Pedrosa, Francisco Miguel Cruz, Lilian K Gutierrez, Ashley J Cuttitta, Andre Monteiro da Rocha, Todd J Herron, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Ofer Binah, Daniel E Michele, Jose Jalife
SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients. eLife 11 (2022)
Alvaro Macias, Andrés Gonzalez-Guerra, Ana I Moreno-Manuel, Francisco M Cruz, Lilian K Gutiérrez, Nieves García-Quintáns, Marta Roche-Molina, Francisco Bermúdez-Jiménez, Vicente Andrés, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Juan A Bernal, Jose Jalife
Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. Nature cardiovascular research 1 (10) (2022)
Ana Isabel Moreno Manuel, Lilian K Gutiérrez, María Linarejos Vera Pedrosa, Francisco Miguel Cruz Uréndez, Francisco José Bermúdez Jiménez, Isabel Martínez Carrascoso, Patricia Sánchez Pérez, Alvaro Macias, José Jalife
Molecular stratification of arrhythmogenic mechanisms in the Andersen Tawil Syndrome. Cardiovascular research (2022)
Alvaro Macias, Andrés Gonzalez-Guerra, Ana I Moreno-Manuel, Francisco M Cruz, Lilian K Gutiérrez, Nieves García-Quintáns, Marta Roche-Molina, Francisco Bermúdez-Jiménez, Vicente Andrés, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Juan A Bernal, Jose Jalife
Kir2.1 dysfunction at the sarcolemma and the sarcoplasmic reticulum causes arrhythmias in a mouse model of Andersen-Tawil syndrome type 1. Nature cardiovascular research 1 (10) (2022)
Alvaro Macias, Alicia de la Cruz, Diego A Peraza, Angela de Benito-Bueno, Teresa Gonzalez, Carmen Valenzuela
KV1.5-KVβ1.3 Recycling Is PKC-Dependent. International journal of molecular sciences 22 (3) (2021)
Amanda Sánchez-López, Carla Espinós-Estévez, Cristina González-Gómez, Pilar Gonzalo, María J Andrés-Manzano, Víctor Fanjul, Raquel Riquelme-Borja, Magda R Hamczyk, Alvaro Macias, Lara Del Campo, Emilio Camafeita, Jesus Vazquez, Anna Barkaway, Loïc Rolas, Sussan Nourshargh, Beatriz Dorado, Ignacio Benedicto, Vicente Andrés
Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome. Circulation 144 (22) (2021)
Víctor Fanjul, Inmaculada Jorge, Emilio Camafeita, Alvaro Macias, Cristina González-Gómez, Ana Barettino, Beatriz Dorado, María Jesús Andrés-Manzano, José Rivera-Torres, Jesus Vazquez, Carlos López-Otín, Vicente Andrés
Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging. Aging cell 19 (9) (2020)